Online Hemodiafiltration Versus Hemodialysis in Removal of Indoxyl Sulfate in Chronic Hemodialysis Patients
Sponsor
Ain Shams University (Other)
Overall Status
Completed
CT.gov ID
NCT05771350
Collaborator
(none)
60
3
2
Study Details
Study Description
Brief Summary
this study aimed to compare the removal of indoxyl sulphate between hemodiafiltration, high flux hemodialysis and low flux hemodialysis
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Actual Enrollment
:
60 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Hemodiafiltration Versus Hemodialysis in Removal of Indoxyl Sulfate in Chronic Hemodialysis Patients
Actual Study Start Date
:
Nov 15, 2016
Actual Primary Completion Date
:
Jan 15, 2017
Actual Study Completion Date
:
Jan 15, 2017
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: online hemodiafiltration
|
Procedure: online hemodiafiltration
20 patients on regular hemodialysis received online hemodiafiltration
|
| Active Comparator: high flux hemodialysis
|
Procedure: high flux hemodialysis
20 patients on regular hemodialysis received high flux hemodialysis
|
| Active Comparator: low flux hemodialysis
|
Procedure: low flux hemodialysis
20 patients on regular hemodialysis received low flux hemodialysis
|
Outcome Measures
Primary Outcome Measures
- dialytic removal of indoxyl sulpahte [one month when all samples were collected]
assessed by the reduction ration of indoxyl sulphate
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 75 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- maintenance hemodialysis patients aged more than 18 years
Exclusion Criteria:
- active illnesses, hospitalization, malignancy
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Ain Shams University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Mohamed sary gharib,
Dr,
Ain Shams University
ClinicalTrials.gov Identifier:
NCT05771350
Other Study ID Numbers:
- FMASU MD 301/2016
First Posted:
Mar 16, 2023
Last Update Posted:
Mar 16, 2023
Last Verified:
Mar 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No