SMSaude: Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique

Sponsor

Absolute Return for Kids (Other)

Overall Status

Completed

CT.gov ID

NCT01910493

Collaborator

Vodacom (Other), United States Agency for International Development (USAID) (U.S. Fed), Department for International Development, United Kingdom (Other)

1,352

Enrollment

Location

Arms

Duration (Months)

71.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Mobile phone SMS are increasingly used to promote positive health behaviour with an aim to improve health outcomes. However, robust data on the efficacy of SMS on health seeking behaviour and patient outcomes in resource-limited settings is sparse. The SMSaude study aims to assess whether regular SMS-reminders improve retention on antiretroviral therapy (ART) and prevention of mother to child transmission of HIV (PMTCT) programmes in Mozambique.

Condition or Disease	Intervention/Treatment	Phase
HIV-positive	Behavioral: SMS reminders	N/A

Detailed Description

SMSaúde is a multisite randomised clinical trial of HIV-infected adults on ART and HIV-infected pregnant women in six clinics in Maputo Province, Mozambique. Eligibility criteria include: currently residing in the province; no plans to move for 12+ months; have own cell-phone; literate; 8-28 weeks pregnant (PMTCT cohort); on first line ART and on ART for >15 days (ART cohort). Patients were interviewed for eligibility, and then randomized (1:1). SMS reminders are sent to the intervention group using software that picks up the patient's next appointment from the electronic patient database. Primary outcomes tested were improved retention in ART care and uptake of all PMTCT services.

Study Design

Study Type:

Interventional

Actual Enrollment :

1352 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Triple (Care Provider, Investigator, Outcomes Assessor)

Primary Purpose:

Treatment

Official Title:

Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique: A Randomized Control Trial

Study Start Date :

Nov 1, 2011

Actual Primary Completion Date :

May 1, 2013

Actual Study Completion Date :

Jun 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: ART no SMS reminders control group	Behavioral: SMS reminders Intervention participants only will be sent text messages to their phones. The content of text messages will have a maximum of 160 characters and not mention HIV and will state the dates for the forthcoming consultations, visits to the pharmacy, lab results, time to take medication and reminders for patients who miss appointments.
Active Comparator: PMTCT no SMS reminders control group	Behavioral: SMS reminders Intervention participants only will be sent text messages to their phones. The content of text messages will have a maximum of 160 characters and not mention HIV and will state the dates for the forthcoming consultations, visits to the pharmacy, lab results, time to take medication and reminders for patients who miss appointments.
Experimental: SMS reminders to PMTCT cohort experimental group	Behavioral: SMS reminders Intervention participants only will be sent text messages to their phones. The content of text messages will have a maximum of 160 characters and not mention HIV and will state the dates for the forthcoming consultations, visits to the pharmacy, lab results, time to take medication and reminders for patients who miss appointments.
Experimental: SMS reminders to ART cohort experimental group	Behavioral: SMS reminders Intervention participants only will be sent text messages to their phones. The content of text messages will have a maximum of 160 characters and not mention HIV and will state the dates for the forthcoming consultations, visits to the pharmacy, lab results, time to take medication and reminders for patients who miss appointments.