YM598 Added to Mitoxantrone/Prednisone to Control Pain in Metastatic Prostate Cancer Patients No Longer Responding to Hormone Therapy
Sponsor
Astellas Pharma Inc (Industry)
Overall Status
Terminated
CT.gov ID
NCT00048659
Collaborator
Astellas Pharma US, Inc. (Industry)
53
Study Details
Study Description
Brief Summary
The purpose of this study is to determine if patients who take YM598 in addition to mitoxantrone and prednisone (standard therapy) experience improvement in the pain associated with prostate cancer metastases in the bone.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
| Phase 2 |
Study Design
Study Type:
Interventional
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double
Primary Purpose:
Treatment
Actual Study Completion Date
:
Jun 1, 2004
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
Male
Accepts Healthy Volunteers:
No
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Alaska Clinical Research Center, LLC | Anchorage | Alaska | United States | |
| 2 | San Bernardino Urological Associates | San Bernardino | California | United States | |
| 3 | Western Clinical Research, Inc. | Torrance | California | United States | |
| 4 | Shands Hospital | Gainesville | Florida | United States | |
| 5 | Sylvester Comprehensive Cancer Center | Miami | Florida | United States | |
| 6 | Georgia Urology,PA Research Institute | Atlanta | Georgia | United States | |
| 7 | University of Chicago, Section of Hematology/Oncology | Chicago | Illinois | United States | |
| 8 | University of Illinois, Department of Urology | Chicago | Illinois | United States | |
| 9 | Michiana Hematology/Oncology | South Bend | Indiana | United States | |
| 10 | The Urologic Institute of New Orleans | Gretna | Louisiana | United States | |
| 11 | Henry Ford Hospital | Detroit | Michigan | United States | |
| 12 | Washington University School of Medicine | St. Louis | Missouri | United States | |
| 13 | Memphis Cancer Center | Memphis | Tennessee | United States | |
| 14 | Virginia Mason Medical Center | Seattle | Washington | United States | |
| 15 | Department of Medical Oncology, The Canberra Hospital | Canberra | Australia | ||
| 16 | Department of Medical Oncology, Concord Hospital Medical Centre | Concord | Australia | ||
| 17 | Division of Oncology Ward, Royal Brisbane Hospital | Herston | Australia | ||
| 18 | Department of Clinical Oncology, Royal North Shore Hospital | St Leonards | Australia | ||
| 19 | Cancer Care Centre, St. George Hospital | Sydney | Australia | ||
| 20 | Department of Medical Oncology, Newcastle Mater Hospital | Waratah | Australia | ||
| 21 | Southern Medical Day Care Centre | Wollongong | Australia | ||
| 22 | Queen Elizabeth Hospital, Clinical Hematology & Oncology | Woodville | Australia | ||
| 23 | Cliniques Universitaires St-Luc, Service d'Urologie | Bruxelles | Belgium | ||
| 24 | Centre Hospitalier Notre Dame et Reine Fabiola, Service d'oncologie | Charleroi | Belgium | ||
| 25 | Centre Paul Papin | Angers | France | ||
| 26 | Service d'Urologie, Hôpital Henri Mondor | Creteil | France | ||
| 27 | Pavillon V, Service d'Urologie et de transplatation, Hôpital Edouard Herriot | Lyon | France | ||
| 28 | Service d' Urologie CHU, Hopital Bichat | Paris | France | ||
| 29 | Krankenhause am Urban, Urologie Dieffenfachstr | Berlin | Germany | ||
| 30 | Dept Urology University of Essen | Essen | Germany | ||
| 31 | Urologische Klinik der MHH | Hannover | Germany | ||
| 32 | Klinikum Mannheim Urology | Mannheim | Germany | ||
| 33 | Mater Misericordiae Hospital | Dublin | Ireland | ||
| 34 | Universitair Medisch Centrum Utrecht, Dienst Medische Oncologie | Utrecht | Netherlands | ||
| 35 | Kilinika Chemioterapii, Centrum Onkologii Instytut im M sklodowskiej Curie | Krakow | Poland | ||
| 36 | Oddzial Chemioterapii | Krakow | Poland | ||
| 37 | Klinika Chemioterapii AM | Lodz | Poland | ||
| 38 | Samodzielny Publiczny Zaklad Opieki zdrowotnej, Wojewodzki Osrodek Onkologii | Opole | Poland | ||
| 39 | Szpital Wojewodzki im Sw Lukasza SP ZOZ Tarnow | Tarnow | Poland | ||
| 40 | Szpital CSK WAMl, Klinika Okologii | Warsaw | Poland | ||
| 41 | Klinika Nowotworow Ukladu | Warszawa | Poland | ||
| 42 | Hospital Clinic i Provincial, Servicio de Oncologia | Barcelona | Spain | ||
| 43 | Hospital General Vall d'Hebron, Servicio de Oncología | Barcelona | Spain | ||
| 44 | Hospital Universitario de Getafe, Servicio de Urologia, Crta | Getafe (Madrid) | Spain | ||
| 45 | Hospital Universitario Príncipe de Asturias, Servicio de Urología | Madrid | Spain | ||
| 46 | Instituto Valenciano de Oncologia, Servicio de Oncologia | Valencia | Spain | ||
| 47 | Department of Urological Research, Derriford Hospital | Devon | United Kingdom | ||
| 48 | Clinical Research Centre, St George's Hospital, Urology Division | London | United Kingdom | ||
| 49 | Department of Urology, St Bartholomew's Hospital | London | United Kingdom | ||
| 50 | Imperial College School of Medicine, Dept Cancer Medicine | London | United Kingdom | ||
| 51 | Department of Urology, East Surrey Hospital | Surrey | United Kingdom | ||
| 52 | Royal Surrey County Hospital | Surrey | United Kingdom | ||
| 53 | St Richard's Hospital | West Sussex | United Kingdom |
Sponsors and Collaborators
- Astellas Pharma Inc
- Astellas Pharma US, Inc.
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00048659
Other Study ID Numbers:
- 598-CL-008
First Posted:
Nov 6, 2002
Last Update Posted:
Jun 7, 2012
Last Verified:
Jun 1, 2012
Keywords provided by ,
,
Additional relevant MeSH terms: