Hot Water Irrigation in Posterior Epistaxis

Sponsor
Assiut University (Other)
Overall Status
Unknown status
CT.gov ID
NCT04151888
Collaborator
(none)
20
17

Study Details

Study Description

Brief Summary

This study was aimed to assess the efficacy and factors affecting the success of hot water irrigation in management of posterior epistaxis.

Condition or Disease Intervention/Treatment Phase
  • Device: Foley catheter

Detailed Description

Epistaxis has been reported to occur in up to 60% of general population.This condition has incidence peaks at ages younger than 10 years and older than 50 years. Epistaxis appears to occur more in males than females . In rare cases massive nasal bleeding can lead to death.

Nasal bleeding usually responds to first aid measures such as compression.When Epistaxis doesn't respond to simple measures. The source of bleeding should be located and treated appropriately. Treatment options to be considered include topical vasoconstriction, chemical cautery, electrocautery, nasal packing, posterior gauze packing, use of balloon system, and arterial ligation or embolization. Hospital admission should be considered with patients with comorbid conditions or complication of blood loss.

Nasal Hot water irrigation was first described by Guice in 1878 as an effective method of treating severe life-threatening epistaxis. However, the technique was already in use by nineteenth century obstetricians as a method of treating postpartum bleeding . In the second half of the twenties century, nasal packing products and the development of endoscopic sinus surgery almost completely replaced the irrigation technique as treatment for posterior epistaxis. However, Stangerup et al. (1996) have demonstrated that hot water irrigation, using temperatures of up to 50°C, produces vasodilation and oedema of the nasal mucosa without the risk of necrosis and accelerating the clotting cascade.

Hot water irrigation had a higher success rate (55 %) in treating posterior epistaxis, compared with nasal packing (44 %) .Using a modified irrigation technique, was able to stop bleeding permanently in up to 82 %of cases of posterior epistaxis, including patients receiving antiplatelet agents or anticoagulants . During a follow-up period of four to 24 months. Furthermore, successful hot water irrigation was associated with less nasal trauma, significantly less pain, fewer surgical procedures and avoidance of a hospital stay.

Study Design

Study Type:
Observational
Anticipated Enrollment :
20 participants
Observational Model:
Other
Time Perspective:
Other
Official Title:
Evaluation of Nasal Hot Water Irrigation in the Management of Posterior Epistaxis
Anticipated Study Start Date :
Jan 30, 2020
Anticipated Primary Completion Date :
Jul 30, 2020
Anticipated Study Completion Date :
Jun 30, 2021

Outcome Measures

Primary Outcome Measures

  1. Effect of hot water irrigation in management of posterior epistaxis [2 years]

    Observation of the patients for 24 hrs after controlling of posterior epistaxis using hot water irrigation if it can control posterior epistaxis or not and this will be confirmed by using coagulation profile and complete blood count

Eligibility Criteria

Criteria

Ages Eligible for Study:
10 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • patients age: > 10 years.

  • Failed first aid measures.

Exclusion Criteria:
  • Patients age < 10 years old.

  • Patients with anterior epistaxis.

  • Patients presented with hemorrhagic shock.

  • Patients presented with post-surgical bleeding.

  • Suspected nasal pathology e.g tumors or trauma.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
RT Fahmy, Resident doctor, Assiut University
ClinicalTrials.gov Identifier:
NCT04151888
Other Study ID Numbers:
  • Epistaxis
First Posted:
Nov 5, 2019
Last Update Posted:
Nov 5, 2019
Last Verified:
Nov 1, 2019
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 5, 2019