Set Volume of Optimal Resistance Exercise to Generate Hypotension

• Sponsor: University of Valencia (Other)
• Overall Status: Completed
• CT.gov ID: NCT03957746
• Collaborator: (none)
• Enrollment: 19
• Location: 1
• Arms: 4
• Actual Duration (Months): 16.7
• Patients Per Site Per Month: 1.1

Study Details

Study Description

Brief Summary

This study evaluates the volume of optimal resistance exercise to generate postexercise hypotension after performing a single exercise in hypertensive elderly subjects. 20 subjects will perform 1 control session and 3 resistance training sessions with different volume: 3, 6 and 9 sets

Condition or Disease	Intervention/Treatment	Phase
Hypertension; Post-Exercise Hypotension; Resistance Training	Other: Resistance training	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 19 participants
• Allocation: Randomized
• Intervention Model: Crossover Assignment
• Masking: Single (Outcomes Assessor)
• Primary Purpose: Treatment
• Official Title: Set Volume of Optimal Resistance Exercise to Generate Hypotension in Hypertensive Elderly Subjects: a Crossover Study
• Actual Study Start Date: May 13, 2020
• Actual Primary Completion Date: Oct 1, 2020
• Actual Study Completion Date: Oct 3, 2021

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 3 sets of resistance exercise	Other: Resistance training; 3, 6 or 9 sets of biceps curl with elastic bands at 20 repetition-maximum (RM)
Experimental: 6 sets of resistance exercise	Other: Resistance training; 3, 6 or 9 sets of biceps curl with elastic bands at 20 repetition-maximum (RM)
Experimental: 9 sets of resistance exercise	Other: Resistance training; 3, 6 or 9 sets of biceps curl with elastic bands at 20 repetition-maximum (RM)
No Intervention: Rest

Outcome Measures

Primary Outcome Measures

1. Blood pressure [Baseline]

2. Blood pressure [Immediately after the end of resistance training session]

3. Blood pressure [30 minutes after the end of resistance training session]

4. Blood pressure [60 minutes after the end of resistance training session]

5. Blood pressure [4 hours after the end of resistance training session]

6. Blood pressure [5 hours after the end of resistance training session]

7. Blood pressure [6 hours after the end of resistance training session]

Secondary Outcome Measures

1. Heart rate [Baseline]

2. Heart rate [Immediately after the end of resistance training session]

3. Heart rate [30 minutes after the end of resistance training session]

4. Heart rate [60 minutes after the end of resistance training session]

5. Heart rate [4 hours after the end of resistance training session]

6. Heart rate [5 hours after the end of resistance training session]

7. Heart rate [6 hours after the end of resistance training session]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 55 Years to 70 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Hypertensive subjects treated with antihypertensive medication

• Controlled blood pressure

• Age between 55 and 70 years old

• Sedentary (less than 150 minutes per week of moderate physical activity and/or 75 minutes per week of vigorous physical activity)

• Non-smokers

• Non-alcoholics

• Informed consent

Exclusion Criteria:

• Any kidney, lung, neurological or psychiatric disease

• Unable to perform exercises

• Participation in other physical activity programs during the study or in the previous 3 months

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Primary Health-Care Center	Rocafort	Valencia	Spain	46111

Sponsors and Collaborators

• University of Valencia

Investigators

• Principal Investigator: Jose Casaña, University of Valencia
• Study Chair: Joaquín Calatayud, University of Valencia
• Study Chair: Alba Cuerda, University of Valencia

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: José Casaña Granell, Director, PhD, University of Valencia
• ClinicalTrials.gov Identifier: NCT03957746
• Other Study ID Numbers: 000018819
• First Posted: May 21, 2019
• Last Update Posted: Oct 5, 2021
• Last Verified: Oct 1, 2021

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Post-Exercise Hypotension; Hypotension

Study Results

No Results Posted as of Oct 5, 2021