Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory

Sponsor
Universität des Saarlandes (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05846425
Collaborator
University Hospital, Basel, Switzerland (Other)
125
3
10

Study Details

Study Description

Brief Summary

The goal of this clinical trial is to learn if yoga-based breathing styles could improve memory performance in adult persons without relevant prior experience in yoga, meditation or similar disciplines and without existing health problems which could hinder the implementation of the breathing exercises.

The main questions it aims to answer are:
  • Can the memory performance get better ?

  • Can the subjective stress level be reduced ?

Participants will complete a memory test while doing a specific nasal and oral breathing.

They will complete a two-week training period after the test with daily nasal or mouth breathing training or no training at all, depending on the group, the are divided into.

Researchers will compare the effect of different breathing styles on memory ability among themselves.

Condition or Disease Intervention/Treatment Phase
  • Other: Nose-breathing training
  • Other: Mouth-breathing training
N/A

Detailed Description

The goal of this clinical trial is to learn about the effect of yoga-based breathing styles on the human brain regarding memory performance in adult persons without relevant prior experience in yoga, meditation or similar disciplines and without existing health problems which could hinder the performance of the breathing exercises.

The main questions it aims to answer are:
  • Is there an improve of memory performance through performing the controlled yoga-based breathing styles ?

  • Is there a relevant reduction of the subjective stress level through performing the controlled yoga-based breathing styles

Participants will complete a memory test while performing controlled nasal and oral breathing.

They will complete a two-week training period after the test with daily nasal or mouth breathing training or no training at all, depending on the group assignment.

Researchers will compare the nasal breathing group to the mouth breathing and the comparison group to see if the nasal breathing results in a significant improvement of the memory capacity.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
125 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Nose-breathing group, Mouth-breathing group, Control groupNose-breathing group, Mouth-breathing group, Control group
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory
Anticipated Study Start Date :
May 1, 2023
Anticipated Primary Completion Date :
Mar 1, 2024
Anticipated Study Completion Date :
Mar 1, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: Nose-breathing

Controlled nose-breathing

Other: Nose-breathing training
13 days of controlled nose-breathing training at a specific frequency with a duration of approximately 15 min a day

Active Comparator: Mouth-breathing

Controlled mouth-breathing

Other: Mouth-breathing training
13 days of controlled mouth-breathing training at a specific frequency with a duration of approximately 15 min a day

No Intervention: Control group

no intervention

Outcome Measures

Primary Outcome Measures

  1. Improvement of learned images [2 weeks]

    Memory improvement by performing the home nasal breathing training. The correctness of the mapping is measured by the percentage correctness of the given answers in the memory test, which takes place promptly after the learning phase and 2 weeks later.

Secondary Outcome Measures

  1. Reduction of subjective stress level [2 weeks]

    The subjective stress level is determined by a subjective stress statement, before and after each learning and retrieval phase, at the first appointment and at the second after 2 weeks.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Willingness to take on the 2-week exercises but no new athletic or meditative activities

  • Yoga-naive and without significant prior experience in various meditative or athletic disciplines that ostensibly involve elements of breath control

  • Access to a device with internet access

  • Signing of the consent form to participate in the study

Exclusion Criteria:
  • Known clinically relevant internal or neurological diseases, especially if associated with chronic pathological oxygenation (e.g. COPD, severe bronchial asthma, sleep apnea, but also CKD).

  • History of drug or alcohol abuse

  • Known psychiatric illnesses that currently require therapy (e.g., pronounced claustrophobia)

  • Medication that could falsify the data collected

  • Lack of consent to take note of possible incidental findings

  • known epileptic seizures, which could be intensified by the visual insertion of the stimuli

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Universität des Saarlandes
  • University Hospital, Basel, Switzerland

Investigators

  • Principal Investigator: Christoph Krick, Dr.rer.med., University of Saarland

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Universität des Saarlandes
ClinicalTrials.gov Identifier:
NCT05846425
Other Study ID Numbers:
  • MST-Breathing Study
First Posted:
May 6, 2023
Last Update Posted:
May 6, 2023
Last Verified:
Apr 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Universität des Saarlandes
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 6, 2023