HMDIH: Hemodynamic Measurements at Different Inclinations of the Head

Sponsor

Federal University of Uberlandia (Other)

Overall Status

Unknown status

CT.gov ID

NCT02046785

Collaborator

(none)

Enrollment

Location

Arm

Duration (Months)

2.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.

Condition or Disease	Intervention/Treatment	Phase
Hypovolemic Shock	Other: 0.9% saline solution	N/A

Detailed Description

Check if values of central venous pressure (CVP), pulse pressure variation (Δpp), heart rate (HR), mean arterial pressure ((PAM) vary in different angles headboards
Compare values of CVP, Δpp, HR and MAP as predictors of blood volume after supply of 500 ml of 0.9% saline solution.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

30 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

Double (Participant, Investigator)

Primary Purpose:

Diagnostic

Official Title:

Comparison of CVP Values , ΔPP and Echocardiographic at Different Angles Headwaters Before and After Volume Challenge

Study Start Date :

Apr 1, 2013

Actual Primary Completion Date :

Sep 1, 2013

Anticipated Study Completion Date :

May 1, 2014

Arms and Interventions

Arm	Intervention/Treatment
Other: 0.9% saline solution comparing values obtained before and after administration of 500 ml of 0.9% saline	Other: 0.9% saline solution comparing values obtained before and after administration of 500 ml of 0.9% salin Other Names: Solution of 0.9% NaCl in distilled water

Arm

Intervention/Treatment

Other: 0.9% saline solution

comparing values obtained before and after administration of 500 ml of 0.9% saline

Other: 0.9% saline solution

comparing values obtained before and after administration of 500 ml of 0.9% salin

Other Names:

Solution of 0.9% NaCl in distilled water

Outcome Measures

Primary Outcome Measures

Different Backrest position's effect on CVP, CO and ∆PP measures [Data collection was performed at admission or within 10 days of hospitalization between September 2013 and February 2014.]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 60 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Being in circulatory shock and have at least one of the following criteria to identify loss of tissue perfusion: systolic blood pressure <90 mmHg or need for vasoactive drugs, urine output below 0.5 ml / kg / h.
Being under sedation, assessed by the scale of Richmond agitation and sedation (RASS) -5, mechanically ventilated in volume control mode with tidal volume between 8 to 12 ml/kg, PEEP to 8 cm H2O.
Tue signing the informed consent by legal guardian.