Identifying Residential Hazards Using Home Test Kits

Sponsor
National Institute of Environmental Health Sciences (NIEHS) (NIH)
Overall Status
Completed
CT.gov ID
NCT00285532
Collaborator
(none)
150
1
60
2.5

Study Details

Study Description

Brief Summary

The purpose of this project is to help families and communities identify and reduce health risks from lead, pesticides and, ultimately, other environmental hazards. We have partnered with the Better Housing League and Baby's Milk Fund in Cincinnati and nationally with the Alliance to End Childhood Lead Poisoning and the National Center for Lead Safe Housing. The first specific aim of this project is to evaluate a sampling kit for families to assess levels of lead and pesticides in their home environment. This aim will strengthen right-to-know laws by providing families with tools to assess environmental contamination in their own homes. The second aim is to increase community awareness of the role of environmental agents in developmental disorders, hearing loss and school problems.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    A cross-sectional random, stratified study design will be used for this project. All children who are younger than 5 years of age and have a venipuncture blood sample taken at the babies Milk Fund Clinic will be eligible for this study. After checking the lists for errors and duplications, we will randomly permute the sampling frame, stratifying on children's blood lead concentration. Stratification will be used to enroll about 33% of the sample with blood lead concentrations below 5 mg/dl, 33% between 5 to 10 mg/dl, and 33% of 10 mg/dl or higher. Stratifying the sample will improve our chances of testing the predictive validity of home sampling kits to identify children who have blood lead concentration > 10 mg/dl collected by families. In addition this study will:

    1. Develop a pesticide wipe sampling kit to accompany our lead-sampling kit.

    2. Evaluate the predictive validity of home sampling kits for lead-contaminated floor dust to identify children who have blood lead levels of 10 mg/dl or higher by community participants compared with repeat samples taken by trained, community workers.

    3. Evaluate the reliability of home sampling kits for pesticides in dust collected by community participants compared with trained, community workers.

    4. Disseminate data on the reliability of home sampling tests and provide tools for families to collect environmental samples for large, population-based studies.

    5. Develop a Healthy Homes Resource Center at the Better Housing League to disseminate information to the community about residential hazards.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    150 participants
    Time Perspective:
    Prospective
    Study Start Date :
    Oct 1, 2001
    Actual Primary Completion Date :
    Oct 1, 2006
    Actual Study Completion Date :
    Oct 1, 2006

    Arms and Interventions

    Arm Intervention/Treatment
    Home test kit

    Outcome Measures

    Primary Outcome Measures

    1. Lead and Pesticide Levels [One time home visit 3-5 days after distribution of kits]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    3 Months to 5 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    Venous blood lead In residence 3 months Child less than 5 years of age Sampler greater than 18 years of age

    Exclusion Criteria:

    Cannot read or understand English Physically unable to conduct field sampling Outside of theGreater Cincinnati area

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 University of Cincinnati Cincinnati Ohio United States 45267-0056

    Sponsors and Collaborators

    • National Institute of Environmental Health Sciences (NIEHS)

    Investigators

    • Principal Investigator: Sandy M Roda, BS, University of Cincinnati

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00285532
    Other Study ID Numbers:
    • 11261-CP-002
    First Posted:
    Feb 2, 2006
    Last Update Posted:
    Nov 18, 2014
    Last Verified:
    Nov 1, 2014
    Keywords provided by , ,
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Nov 18, 2014