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Images in Extracranial Artery Stenosis

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT00173927
Collaborator
(none)
100
Enrollment
1
Location

Study Details

Study Description

Brief Summary

The goals of this trial are:

  1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.

  2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    100 participants
    Time Perspective:
    Prospective
    Official Title:
    The Differences in Images of Vertebral Artery Stenosis and Carotid Artery Stenosis Pre- and Post-Percutaneous Transluminal Angioplasty and the Gene Expression Patterns in Peripheral White Blood Cells
    Study Start Date :
    Mar 1, 2004

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      30 Years to 90 Years
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      • Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.
      Exclusion Criteria:

      • Acute systemic illness

      • Creatinine > 3 mg/dl

      • Unable to tolerate the tests (including MRI and PET/computed tomography [CT] scans)

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 National Taiwan University Hospital Taipei Taiwan 10012

      Sponsors and Collaborators

      • National Taiwan University Hospital

      Investigators

      • Principal Investigator: Hsien-Li Kao, MD, National Taiwan University Hospital

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00173927
      Other Study ID Numbers:
      • 9261701156
      • NTUH 94N04
      First Posted:
      Sep 15, 2005
      Last Update Posted:
      Oct 30, 2007
      Last Verified:
      Sep 1, 2005
      Keywords provided by , ,
      extracranial atherosclerosis
      imaging
      biomarkers
      Additional relevant MeSH terms:
      Atherosclerosis

      Study Results

      No Results Posted as of Oct 30, 2007