Imaging of Soft Tissues
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the potential importance of tissue elasticity in the assessment of soft tissues including muscles, tendons and ligaments and other soft tissue structures.
The evaluation of tissue elasticity (easily stretched or moveable) may assist in assessment of various soft tissue structures, such as fatty atrophy of muscles, tendon/ligamentous injury and healing and other soft tissue structures.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
This is a prospective study that will recruit males and females 18 years of age and older who present to the department for a clinically indicated ultrasound of a superficial soft tissue abnormality with prior or following MRI / CT assessment ordered for clinical purposes.
The elasticity properties of tissues depend on their molecular building blocks and on the organization of these blocks. Injuries, disease etc are known to be associated with changes in tissue elasticity. Little research has been done on the potential of sonoelastographic (elasticity ultrasound imaging) assessment of normal, injured or healing muscles, tendons or ligaments.
Elasticity changes in muscle, ligaments and tendons following injury may have implication on the choice of treatment and help in determine how the length of time needed to heal from an injury.
Stiffness/elasticity of the tissue can be assessed by mechanical excitation with measurement of resultant tissue motion. Reconstruction of the elastic deformability (strain imaging) in real time ultrasound is known as sonoelastography.
Elasticity ultrasound imaging will be performed on the area being evaluated clinically.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Evaluation of tissue elasticity Evaluate the potential importance of tissue elasticity in the assessment soft tissue structures. |
Other: Ultrasound examination
Sonoelastrography is an ultrasound examination that can determine the elasticity of soft tissue. This examination takes approximately 10 minutes to complete.
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Outcome Measures
Primary Outcome Measures
- To assess the potential importance of Sonoelastography in evaluating tissue injury or abnormalities of soft tissues. [hours]
Eligibility Criteria
Criteria
Inclusion Criteria:
- Subjects who present for a clinically ordered ultrasound for evaluation of a soft tissue abnormality.
Exclusion Criteria:
- Women who are pregnant
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Michigan Hospital | Ann Arbor | Michigan | United States | 48109 |
Sponsors and Collaborators
- University of Michigan
Investigators
- Principal Investigator: Yoav Morag, M.D., University of Michigan
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- HUM 20943