OBSTETRICON: Impact of Age at Conization on Obstetrical Outcome: A Case-Control Study
Study Details
Study Description
Brief Summary
The maternity ward attached to the colposcopy clinic was also the obstetrical referral center for the region and carried out approximately 2500 deliveries per year. The aim of the study was to assess whether an age younger than 25 years at conization affected future pregnancy outcome as an independent factor. A retrospective study of 115 women who underwent both loop electrosurgical excision procedure (LEEP) and subsequent pregnancy follow-up in a referral center was conducted. Two groups were considered: patients younger than 25 years at the time of the loop electrosurgical excision procedure (n = 42) and 25 years or older (n = 73). Analyzed data were occurrence of preterm adverse obstetrical event and, specifically, preterm labor (PL) and preterm rupture of membranes; stratification based on term of occurrence was performed: less than 37 weeks of amenorrhea (WA), less than 34 WA, and less than 26 WA.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
The investigators conducted a retrospective observational study between January 2008 and December 2015 in a French colposcopic referral academic hospital. The maternity ward attached to the colposcopy clinic was also the obstetrical referral center for the region and carried out approximately 2500 deliveries per year. The aim of the study was to assess whether an age younger than 25 years at conization affected future pregnancy outcome as an independent factor. A retrospective study of 115 women who underwent both loop electrosurgical excision procedure (LEEP) and subsequent pregnancy follow-up in a referral center was conducted. Two groups were considered: patients younger than 25 years at the time of the loop electrosurgical excision procedure (n = 42) and 25 years or older (n = 73). Analyzed data were occurrence of preterm adverse obstetrical event and, specifically, preterm labor (PL) and preterm rupture of membranes; stratification based on term of occurrence was performed: less than 37 weeks of amenorrhea (WA), less than 34 WA, and less than 26 WA.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| < 25 years 42 patients younger than 25 years at the time of loop electrosurgical excision procedure |
Other: loop electrosurgical excision procedure
A retrospective study of 115 women who underwent both loop electrosurgical excision procedure (LEEP) and subse- quent pregnancy follow-up in a referral center was conducted.
|
| > 25 years 73 patients 25 years or older at the time of loop electrosurgical excision procedure |
Other: loop electrosurgical excision procedure
A retrospective study of 115 women who underwent both loop electrosurgical excision procedure (LEEP) and subse- quent pregnancy follow-up in a referral center was conducted.
|
Outcome Measures
Primary Outcome Measures
- occurrence of preterm adverse obstetrical event in the group of women younger than < 25 years old [18 weeks]
The objective of this study was to evaluate if an age younger than < 25 years old at the time of loop electrosurgical excision procedure affected future pregnancy and can have impact on th early preterm adverse obstetrical events.
Eligibility Criteria
Criteria
Inclusion Criteria:
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female pregnant
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underwent loop electrosurgical excision procedure during the studied period
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delivered in their institution
Exclusion Criteria:
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patients having delivered elsewhere after loop electrosurgical excision procedure
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Early miscarriages (<14 weeks of amenorrhea )
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Centre Hospitalier Universitaire, Amiens
Investigators
- Principal Investigator: Jean Gondry, MD, PhD, CHU AMIENS
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- PI2017_843_0049