THOUGHTS: Impact of Attention on Obsessive Thoughts Through THOUGHT

Sponsor

Assistance Publique - Hôpitaux de Paris (Other)

Overall Status

Recruiting

CT.gov ID

NCT05944172

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

2.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by the environment in patients with obsessive disorder compulsive disorder (OCD) and patients without OCD" Validation of THOUGHTS.

Condition or Disease	Intervention/Treatment	Phase
Obsessive Compulsive Disorder OCD

Detailed Description

We developed a scale (the THOUGHTS) dedicated to allow a subject to subjectively measure its level of mind wandering/daydreaming (and obsessions in case of OCD patients) during different everyday situations. This scale is developed for 15 years old or older students (high school, university). Indeed, common point in everyday life was easier to find in students than in workers where lifestyle can be very divergent according to the job type. Through this scale, we will first detect the situations the more associated with mind wandering/daydreaming in healthy subjects. To do that, we will first find the 50% and the 25% of the situations the most associated with mind wandering. This step will allow us to distinguish two types of situations: situations with high level of mind wandering/daydreaming vs. situations with low level of mind wandering/daydreaming. Then we will do the same analyses in OCD patients to see if situations of high level of mind wandering are the same in both groups. Finally, we will compare the level of obsessions in OCD patients in these two types of situations (linked with high vs. low mind wandering, as defined by healthy subject, OCD patients and both populations).

To make these analyses, we will recruit 40 young OCD people (still students) from only one center, all diagnosed through DSM-5 criteria by a same senior and experimented child and adolescent psychiatrist and 40 matched healthy subjects.

For OCD patients: all comorbidities will be allowed except those associated with hallucinations or delusions: schizophrenia or bipolar disorder will then not be allowed. Neurological disorders will not be allowed too. Y-BOCS or CY-BOCS will be get and analyzed to find if severity could influence our results.

Healthy controls: they will be recruited to be matched with the OCD patients. No psychiatric or neurologic disorder will be allowed. No psychotropic or neurologic treatment will be allowed.

Finally, in terms of statistics, we will use non parametric tests.

Study Design

Study Type:

Observational

Anticipated Enrollment :

80 participants

Observational Model:

Case-Control

Time Perspective:

Cross-Sectional

Official Title:

Thoughts Content in OCD: What Links Between Mind Wandering and Obsessions

Actual Study Start Date :

Feb 20, 2023

Anticipated Primary Completion Date :

Feb 20, 2026

Anticipated Study Completion Date :

Feb 20, 2026

Outcome Measures

Primary Outcome Measures

Comparison of the obsession level (as measured by the THOUGHTS-scale) in situations associated with high level mind wandering/daydreaming and situations associated with low level of mind wandering/daydreaming [metrics are measured only one time, directly after the subject accept to participate to the study.]
demonstrate that in patients with OCD, the level of presence of obsessions is different during active and passive situations, using the THOUGHT questionnaire - scale.

Secondary Outcome Measures

: Effect of OCD severity on the link between OCD and mind wandering/daydreaming [measured only one time, directly after the subject accept to participate to the study.]
Separated OCD patients in 2 groups according to their YBOCS severity to see if obsessions replace mind wandering in the same manner (the same situation and at the same level)

Eligibility Criteria

Criteria

Ages Eligible for Study:

15 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

For pathological patients:

Over the age of 15
Suffering from OCD (obsessive compulsive disorder)
All comorbidities are possible except schizophrenia, bipolarity and anorexia nervosa
Consultant or admitted to Albert Chenevier Hospital

For patients who are not affected by the disease:

Over 15 years of age
Consulted or admitted to GH Henri Mondor

Exclusion Criteria:

For pathological patients:

Refusal to participate by the patient (and/or legal representative in the case of minors)
Presence of schizophrenia, bipolar or anorexia nervosa

For patients who are free of these conditions:

Presence of psychiatric or neurological pathology
Refusal to participate on the part of the patient (and/or on the part of the legal representative in the case of minors)

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Albert Chenevier hospital	Créteil	Creteil	France	94010

Sponsors and Collaborators

Assistance Publique - Hôpitaux de Paris

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Assistance Publique - Hôpitaux de Paris

ClinicalTrials.gov Identifier:

NCT05944172

Other Study ID Numbers:

APHP220613

First Posted:

Jul 13, 2023

Last Update Posted:

Jul 13, 2023

Last Verified:

Jul 1, 2023

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Assistance Publique - Hôpitaux de Paris

OCD

wandering

daydreaming

Additional relevant MeSH terms:

Obsessive-Compulsive Disorder

Study Results

No Results Posted as of Jul 13, 2023