Impact of Treatment With Colistin on Mortality Bacteremia Multiresistant Acinetobacter Baumannii Sensitive Colistin in Patients Critical

• Sponsor: Maimónides Biomedical Research Institute of Córdoba (Other)
• Overall Status: Completed
• CT.gov ID: NCT02573064
• Collaborator: (none)
• Enrollment: 113

Study Details

Study Description

Brief Summary

The present study was designed to study the impact of empirical treatment with colistin empirical monotherapy and combined treatment with tigecycline and vancomycin on mortality of bacteremia Multiresistant Acinetobacter Baumannii . The main objective was to evaluate the efficacy of empirical treatment with colistin and combined targeted therapy. The different therapeutical interventions were administered following the routine clinical practice in the medical centre and the investigator did not assign specific interventions to the subjects of the study.

Condition or Disease	Intervention/Treatment	Phase
Acinetobacter Infections	Drug: Colistin; Drug: Tigecycline; Drug: Vancomycin

Study Design

• Study Type: Observational
• Actual Enrollment: 113 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Study Start Date: Jan 1, 2010
• Actual Primary Completion Date: Dec 1, 2012

Outcome Measures

Primary Outcome Measures

1. All-cause 30-day mortality (crude). [30 days]

Secondary Outcome Measures

1. All-cause 14 day mortality (crude). [14 days]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 16 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Critics included patients ≥ 16 years with monomicrobial bloodstream infections by multiresistant acinetobacter baumannii to carbapenems and sensitive to colistin accompanied by systemic inflammatory response syndrome, provided they have received targeted treatment with colistin.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Maimónides Biomedical Research Institute of Córdoba

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Maimónides Biomedical Research Institute of Córdoba
• ClinicalTrials.gov Identifier: NCT02573064
• Other Study ID Numbers: FCO-COL-2015-01
• First Posted: Oct 9, 2015
• Last Update Posted: Oct 9, 2015
• Last Verified: Oct 1, 2015

• Additional relevant MeSH terms: Acinetobacter Infections; Vancomycin; Colistin; Tigecycline

Study Results

No Results Posted as of Oct 9, 2015