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The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle

Sponsor
Grigore T. Popa University of Medicine and Pharmacy (Other)
Overall Status
Active, not recruiting
CT.gov ID
NCT05685823
Collaborator
(none)
140
Enrollment
1
Location
49
Anticipated Duration (Months)
2.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The objective of this study is to evaluate a group of patients with chronic kidney disease in stages 3-5 by conventional 2D echocardiography, tissue Doppler techniques and speckle tracking - LV GLS and determine the correlation of ultrasound parameters with mortality. Additionally, fibrosis-related biomarkers will be studied in this population.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    140 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle
    Actual Study Start Date :
    Oct 1, 2019
    Actual Primary Completion Date :
    Jan 1, 2021
    Anticipated Study Completion Date :
    Oct 31, 2023

    Outcome Measures

    Primary Outcome Measures

    1. Variation of GLS [3 years]

    2. All-cause mortality [3 years]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • eGFR < 15 ml/min/1.73m2 (CKD - EPI)

    • NYHA class I-II

    • Hemodynamic stability

    Exclusion Criteria:

    • age < 18 years old

    • poor acoustic window

    • atrial fibrillation

    • recent Acute Myocardial Infarction

    • pacemaker

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Gr T Popa University of Medicine and Pharmacy Iasi Romania

    Sponsors and Collaborators

    • Grigore T. Popa University of Medicine and Pharmacy

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Ureche Carina, MD, Grigore T. Popa University of Medicine and Pharmacy
    ClinicalTrials.gov Identifier:
    NCT05685823
    Other Study ID Numbers:
    • EchoESRD
    First Posted:
    Jan 17, 2023
    Last Update Posted:
    Jan 17, 2023
    Last Verified:
    Jan 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Kidney Diseases
    Renal Insufficiency, Chronic
    Cardiovascular Diseases

    Study Results

    No Results Posted as of Jan 17, 2023