HOSPITALUS: Evaluation of the Impact of Lung Ultrasound on Mortality and Rehospitalization in Patients Admitted to the Emergency Department With Dyspnea

Sponsor

Hospices Civils de Lyon (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05787665

Collaborator

(none)

385

Enrollment

Location

Anticipated Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Dyspnea is a frequent reason for referral to emergency departments, leading to a 30-day mortality rate of up to 10% and a 3-month rehospitalization rate of over 30%.

Multiple etiologies, as well as poor performance of clinical examination and chest radiography, lead to a diagnostic error rate of nearly 30% at the end of emergency department care. These diagnostic errors lead to rehospitalization and an excess mortality rate of more than 50% compared to patients with a correct initial diagnosis, which is explained in particular by the use of inappropriate therapies.

Lung ultrasound is a rapid, non-irradiating, non-invasive, inexpensive, reproducible imaging test that can be used at the bedside. It has a better diagnostic performance than chest radiography, commonly performed in emergency departments.The immediate benefit of lung ultrasound for the most common diagnoses in emergency medicine has already been demonstrated.

From an organizational point of view, a few studies have shown a benefit of lung ultrasound in reducing the time spent in emergency departments and the number of additional examinations necessary for the final diagnosis. However, there is no data in the literature on the longer term impact of its use in the emergency department.

The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month mortality and rehospitalization as part of the diagnostic process for patients admitted to the emergency department with dyspnea.

Condition or Disease	Intervention/Treatment	Phase
Dyspnea	Other: phone call at 3 months

Study Design

Study Type:

Observational

Anticipated Enrollment :

385 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Evaluation of the Impact of Lung Ultrasound on Mortality and Rehospitalization in Patients Admitted to the Emergency Department With Dyspnea: a Prospective Observational Cohort

Anticipated Study Start Date :

May 1, 2023

Anticipated Primary Completion Date :

May 1, 2024

Anticipated Study Completion Date :

May 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
With Lung Ultrasonography Patient who meet inclusions criteria, and which lung ultrasonography were performed during their medical care in Emergency Department	Other: phone call at 3 months patients will be called at 3 months to know if they are alive and to know if they have been rehospitalized
Without Lung Ultrasonography Patient who meet inclusions criteria, and which lung ultrasonography were not performed during their medical care in Emergency Department.	Other: phone call at 3 months patients will be called at 3 months to know if they are alive and to know if they have been rehospitalized

Arm

Intervention/Treatment

With Lung Ultrasonography

Patient who meet inclusions criteria, and which lung ultrasonography were performed during their medical care in Emergency Department

Other: phone call at 3 months

patients will be called at 3 months to know if they are alive and to know if they have been rehospitalized

Without Lung Ultrasonography

Patient who meet inclusions criteria, and which lung ultrasonography were not performed during their medical care in Emergency Department.

Other: phone call at 3 months

patients will be called at 3 months to know if they are alive and to know if they have been rehospitalized

Outcome Measures

Primary Outcome Measures

The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month mortality as part of the diagnostic process for patients admitted to the emergency department with dyspnea. [at 3 months]
The primary endpoint is the rate of mortality at 3 months.
The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month rehospitalization as part of the diagnostic process for patients admitted to the emergency department with dyspnea. [at 3 months]
the primary endpoint is the rate of rehospitalization at 3 months

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Age ≥ 18 years
Admission to the emergency department with dyspnea defined by:

The functional sign of dyspnea experienced by the patient; Or a clinical sign of respiratory distress.

Non-opposition of the patient or patient's family if the patient isn't able

Exclusion Criteria:

Trauma-induced dyspnea;
Patient being on palliative care;
Patient with criteria for initial resuscitation with admission to a critical care unit;
Pregnant women, women in labour or nursing mothers;
Persons deprived of liberty by judicial or administrative decision;
Persons under psychiatric care;
Persons admitted to a health or social institution for purposes other than research;
Persons of full age subject to a legal protection measure (guardianship, curatorship);