PR-ILD: The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease

Sponsor

University of California, San Francisco (Other)

Overall Status

Completed

CT.gov ID

NCT01055730

Collaborator

(none)

Enrollment

Locations

Duration (Months)

Patients Per Site

0.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine if pulmonary rehabilitation has any effect on breathlessness, quality of life, physical function and depression in persons with interstitial lung disease.

Condition or Disease	Intervention/Treatment	Phase
Interstitial Lung Disease	Other: Pulmonary rehabilitation

Study Design

Study Type:

Observational

Actual Enrollment :

54 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease: A Prospective Cohort Study

Study Start Date :

Feb 1, 2010

Actual Primary Completion Date :

Jan 1, 2013

Actual Study Completion Date :

Jan 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Pulmonary rehabilitation	Other: Pulmonary rehabilitation Structured education and supervised exercise program, lasting between 6 and 9 weeks.

Arm

Intervention/Treatment

Pulmonary rehabilitation

Other: Pulmonary rehabilitation

Structured education and supervised exercise program, lasting between 6 and 9 weeks.

Outcome Measures

Primary Outcome Measures

6-minute walk distance [Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation]
Quality of life [Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation]

Secondary Outcome Measures

Dyspnea [Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation]
Depression [Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation]

Eligibility Criteria

Criteria

Ages Eligible for Study:

19 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Adults (> 18 years old) with a diagnosis of ILD who are referred to a participating PR program

Exclusion Criteria:

Inability to provide informed consent
Inability to read and write English
Any other medical condition that significantly limits the subject's ability to perform the functional measures
Emphysema / Chronic bronchitis (FEV1 / FVC ratio < 60%)
Previous pulmonary rehabilitation

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	John Muir Health	Concord	California	United States	94520
2	Seton Pulmonary & Cardiac Rehabilitation	Daly City	California	United States	94015
3	Yale University School of Medicine	New Haven	Connecticut	United States	06520-8057
4	Duke University Medical Center	Durham	North Carolina	United States	27710
5	Inova Fairfax Hospital	Falls Church	Virginia	United States	22042
6	University of British Columbia	Vancouver	British Columbia	Canada	V6Z 1Y6

Sponsors and Collaborators

University of California, San Francisco

Investigators

Principal Investigator: Harold R Collard, MD, University of California, San Francisco
Principal Investigator: Christopher J Ryerson, MD, University of California, San Francisco
Principal Investigator: Chris Garvey, FNP, Seton Pulmonary & Cardiac Rehabilitation