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Efficacy of Diode Laser in Peri-implantitis

Sponsor
Istanbul University (Other)
Overall Status
Completed
CT.gov ID
NCT02362854
Collaborator
Istanbul University Research Fund (Other)
10
Enrollment
1
Location
2
Arms
52.9
Duration (Months)
0.2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis. A prospective clinical, radiographic and microbiologic split-mouth study was conducted to test the following null hypothesis; adjunct application of a diode laser, in the conventional treatment of peri-implantitis, are not associated with a statistically significant difference regarding the microbial counts, marginal bone loss and peri-implant parameters.

Condition or Disease Intervention/Treatment Phase
  • Procedure: Conventional peri-implantitis treatment
  • Device: DL application in peri-implantitis
 N/A

Detailed Description

Efficacy of a diode laser (DL) in peri-implantitis was investigated. 48 implants diagnosed with peri-implantitis were included. In addition to the conventional scaling and debridement, random 24 implants were lased by a DL. Periodontal indexes, microbiologic specimens and radiographs were used for assessment. Baseline parameters were similar between groups. After six months laser group revealed higher MBL than the control group. Microbiota of the implants were found unchanged after one month. DL appears to have no additional positive influence on the peri-implantitis treatment.

Study Design

Study Type:
Interventional
Actual Enrollment :
10 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
A Randomized Clinical Trial of an Adjunct Diode Laser Application in the Treatment of Peri-implantitis.
Study Start Date :
Feb 1, 2010
Actual Primary Completion Date :
Jul 1, 2014
Actual Study Completion Date :
Jul 1, 2014

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Conventional peri-implantitis treatment

Peri-implantitis treatment according to the Cumulative interceptive supportive (CIST) therapy.

Procedure: Conventional peri-implantitis treatment
Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.
Other Names:
  • CIST treatment protocol

    		•
    Experimental: DL application in peri-implantitis

    Adjunct Diode Laser application.

    Device: DL application in peri-implantitis
    Diode laser application in the diseased implants.

    Outcome Measures

    Primary Outcome Measures

    1. Bacterial counts [One month]

      Bacterial load around the the diseased implants will be determined at the initiation of the study. The assessment will be performed after one months

    Secondary Outcome Measures

    1. Marginal Bone loss [Six months]

      The marginal bone loss around the diseased implants will be assessed after six months to analyse any bone level change.

    Other Outcome Measures

    1. Peri-implant health indexes [one and six months]

      Bleeding on probing, probing depth and plaque index which determined at the initiation of the study will be re-evaluated after one and six months to asees the effect of the variables

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • 18 years and older

    • No local and systemic health problems prohibit the study interventions

    • Bi-lateral implants with peri-implantitis diagnosis

    Exclusion Criteria:
    • Local and systemic health problems prohibiting the study interventions

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Department of Oral Implantology, Faculty of Dentistry, Istanbul University Istanbul Capa Turkey 34093

    Sponsors and Collaborators

    • Istanbul University
    • Istanbul University Research Fund

    Investigators

    • Study Chair: Volkan Arısan, Ass.Prof.Dr., Istanbul University, Faculty of Dentistry
    • Study Director: Cuneyt Karabuda, Prof.Dr., Istanbul University, Faculty of Dentistry

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    Volkan Arisan, Assoc.Prof.Dr, Istanbul University
    ClinicalTrials.gov Identifier:
    NCT02362854
    Other Study ID Numbers:
    • IstanbulU
    First Posted:
    Feb 13, 2015
    Last Update Posted:
    Feb 13, 2015
    Last Verified:
    Feb 1, 2015
    Keywords provided by Volkan Arisan, Assoc.Prof.Dr, Istanbul University
    dental implant
    laser
    diode laser
    peri-implantitis
    bacterial count
    Additional relevant MeSH terms:
    Alveolar Bone Loss
    Peri-Implantitis

    Study Results

    No Results Posted as of Feb 13, 2015