Incidence of Postoperative Hypothermia and Associated Factors in Adult Patients Undergoing Surgery in Siriraj Hospital

Sponsor
Siriraj Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT04307095
Collaborator
(none)
742
1
24
30.9

Study Details

Study Description

Brief Summary

Inadvertent postanesthetic hypothermia is unintentional drop in core body temperature <36C (96.8F) immediately following an operation, caused by multiple factors, and had lead to negative outcomes. In our institute, a study in 2011 reported an incidence of postoperative hypothermia in PACU of 45.4% (95% CI 39.61%- 51.23%). After that, various interventions aimed to prevent perioperative hypothermia were implemented. This study is initiated to determine the incidence of postoperative hypothermia and associated factors of postoperative hypothermia in adult patients underwent surgery at Siriraj hospital.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Inadvertent postanesthetic hypothermia is unintentional drop in core body temperature <36C (96.8F) immediately following an operation, which is a common problem in post anesthesia care unit (PACU). It has been implicated in negative outcomes in surgical patients, including prolonged effects of intraoperative anesthetic medication, increased insulin resistance, postoperative morbidity, delayed surgical wound healing; and prolonged stay in the recovery room and hospital1-7.

    In the operating room (OR), patients have to expose to a low ambient temperature with little or no clothing, evaporation from the surgical area, an irrigated fluid in surgical area; and an administration of intravenous fluids. Moreover, many anesthetic agents have an influence on the autonomic thermoregulatory mechanism which causes vasodilatation. All these factors promote patients' unintentional loss of heat and cause hypothermia.

    Even of a lot of efforts to keep patients warm intraoperatively and minimize hypothermia including optimizing ambient OR temperature and using of various warming devices, the incidences of postoperative hypothermia in PACU are still high with the reported magnitude ranges from 50%- 90%7. In Siriraj hospital, a study in 2011 reported an incidence of postoperative hypothermia in PACU of 45.4% (95% CI 39.61%- 51.23%)8. After that, various interventions aimed to prevent perioperative hypothermia were implemented such as maintaining the ambient room temperature of an OR; warming intravenous fluids, blood products, and irrigants; heated, humidified anesthetic gases; and using warming blankets, forced-air warming, layering drapes and head wraps. This study is initiated to determine the incidence of postoperative hypothermia and associated factors of postoperative hypothermia in adult patients underwent surgery at Siriraj hospital.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    742 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Retrospective
    Official Title:
    Incidence of Postoperative Hypothermia and Associated Factors in Adult Patients Undergoing Surgery in Siriraj Hospital
    Actual Study Start Date :
    Jan 16, 2020
    Actual Primary Completion Date :
    Nov 1, 2021
    Actual Study Completion Date :
    Jan 15, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Body temperature [1 min]

      Body temperature after admit in PACU

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • All patients >18 years undergoing surgery with anesthesia service

    • Stay at Postanesthetic care unit of Syamindra building, fifth floor, Siriraj hospital

    Exclusion Criteria:
    • Procedure performed under local anesthesia

    • Patients with missing data of temperature

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Siriraj Hospital, Faculty of medicine Siriraj hospital, Mahidol University Bangkok Thailand 10700

    Sponsors and Collaborators

    • Siriraj Hospital

    Investigators

    • Principal Investigator: Mingkwan Wongyingsinn, MD, Faculty of Medicine Siriraj Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Mingkwan Wongyingsinn, MD, Associate Professor, Siriraj Hospital
    ClinicalTrials.gov Identifier:
    NCT04307095
    Other Study ID Numbers:
    • IRB889
    First Posted:
    Mar 13, 2020
    Last Update Posted:
    May 19, 2022
    Last Verified:
    May 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Mingkwan Wongyingsinn, MD, Associate Professor, Siriraj Hospital
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of May 19, 2022