Incidence and Risk Factors of Early Onset Colorectal Cancer

Sponsor

Hospital Frydek-Mistek (Other)

Overall Status

Completed

CT.gov ID

NCT05184751

Collaborator

(none)

18,257

Enrollment

119

Actual Duration (Months)

Study Details

Study Description

Brief Summary

Early onset colorectal cancer (cancer in person younger than 50 years) has increasing incidence last years. The aim of our study was to assess the real-life incidence of early onset colorectal cancer, advanced neoplasias (colorectal cancer and/or advanced adenoma) and all neoplastic lesions in total in a single non-university endoscopic center.

Condition or Disease	Intervention/Treatment	Phase
Colorectal Neoplasms	Other: colonoscopy

Detailed Description

The investigators retrospectively assessed the incidence of all neoplastic lesions, advanced neoplasias and colorectal cancer in population under 50 years of age compared to population 50 years and older. The investigators collected the data from all colonoscopic examinations performed in non-university hospital Frydek-Mistek from January 2012 to the end of June 2021.

Study Design

Study Type:

Observational

Actual Enrollment :

18257 participants

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Incidence and Risk Factors of Early Onset Colorectal Cancer

Actual Study Start Date :

Jan 1, 2012

Actual Primary Completion Date :

Jun 30, 2021

Actual Study Completion Date :

Dec 1, 2021

Arms and Interventions

Arm	Intervention/Treatment
50 years and over patients who underwent colonoscopic examination aged 50 years and over	Other: colonoscopy
under 50 years patients who underwent colonoscopic examination aged under 50 years	Other: colonoscopy

Arm

Intervention/Treatment

50 years and over

patients who underwent colonoscopic examination aged 50 years and over

Other: colonoscopy

under 50 years

patients who underwent colonoscopic examination aged under 50 years

Other: colonoscopy

Outcome Measures

Primary Outcome Measures

incidence of early onset colorectal neoplasias, risk factors [10 years]
the real-life incidence of early onset colorectal cancer, advanced neoplasias (colorectal cancer and/or advanced adenoma) and all neoplastic lesions in total in a single non-university endoscopic center, the risk of sex and family history of colorectal cancer

Eligibility Criteria

Criteria

Ages Eligible for Study:

4 Years to 97 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria: all patient who underwent colonoscopic examination clear indication for colonoscopy

Exclusion Criteria: not able to underwent colonoscopy

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Hospital Frydek-Mistek

Investigators

Principal Investigator: Ivana Mikoviny Kajzrlikova, Hospital Frydek-Mistek

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Ivana Mikoviny Kajzrlikova, MD, PhD, MD, PhD, Head of endoscopic department, Hospital Frydek-Mistek

ClinicalTrials.gov Identifier:

NCT05184751

Other Study ID Numbers:

Early onset colorectal cancer

First Posted:

Jan 11, 2022

Last Update Posted:

Jan 31, 2022

Last Verified:

Jan 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Undecided

Plan to Share IPD:

Undecided

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Colorectal Neoplasms

Study Results

No Results Posted as of Jan 31, 2022