Indirect Measurement of Respiratory Quotient in Coelioscopic Surgery

• Sponsor: Centre Hospitalier Universitaire, Amiens (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT03751579
• Collaborator: (none)
• Enrollment: 50
• Anticipated Duration (Months): 5.9

Study Details

Study Description

Brief Summary

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured RQ from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room.

But, because of artificially increase of carbon dioxide due to insufflation, coelioscopic surgery was an exclusion criteria of our pilot study.

However, no study has examined the impact of coelioscopy on the indirect measurement of RQ

Condition or Disease	Intervention/Treatment	Phase
Respiratory Quotient Measurement	Procedure: coelioscopic surgery

Study Design

• Study Type: Observational
• Anticipated Enrollment: 50 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Validation of the Respiratory Quotient Measurement Measured Indirectly in Coelioscopic Surgery
• Anticipated Study Start Date: Nov 1, 2018
• Anticipated Primary Completion Date: May 1, 2019
• Anticipated Study Completion Date: May 1, 2019

Outcome Measures

Primary Outcome Measures

1. Indirect respiratory quotient by measurement of VO2 and VCO2 [during coelioscopic surgery]

   The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2)

Secondary Outcome Measures

1. occurence of at least one post-operative complication [through study completion, an average of 6 months]

   the aim is to predict the occurence of at least one complication with the use of indirect respiratory quotient

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All

Inclusion Criteria:

• Age>18 years old

• Adults admitted to the operating room for coelioscopic surgery

Exclusion Criteria:

• Cardiac and thoracic surgery

• Preoperative oxygen therapy

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Centre Hospitalier Universitaire, Amiens

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Centre Hospitalier Universitaire, Amiens
• ClinicalTrials.gov Identifier: NCT03751579
• Other Study ID Numbers: PI2018_843_0046
• First Posted: Nov 23, 2018
• Last Update Posted: Nov 23, 2018
• Last Verified: Nov 1, 2018

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Centre Hospitalier Universitaire, Amiens: coelioscopic; surgery complications; respiratory quotient

Study Results

No Results Posted as of Nov 23, 2018