Individual Differences in Diabetes Risk: Role of Slow WaveSleep

• Sponsor: University of Chicago (Other)
• Overall Status: Completed
• CT.gov ID: NCT00989378
• Collaborator: (none)
• Enrollment: 5
• Location: 1
• Duration (Months): 22
• Patients Per Site Per Month: 0.2

Study Details

Study Description

Brief Summary

This study will examine the relationship between the amount of slow wave sleep (deep sleep) and the ability of the body to bring the blood sugar level to a normal range after receiving glucose.

Condition or Disease	Intervention/Treatment	Phase
Sleep; Diabetes	Behavioral: baseline study

Study Design

• Study Type: Observational
• Actual Enrollment: 5 participants
• Observational Model: Cohort
• Official Title: Ancillary Studies to Major Ongoing NIDDK Clinical Research Studies
• Study Start Date: Nov 1, 2008
• Actual Primary Completion Date: Sep 1, 2010
• Actual Study Completion Date: Sep 1, 2010

Arms and Interventions

Arm	Intervention/Treatment
control normal healthy men and women	Behavioral: baseline study; normal bedtimes

Outcome Measures

Primary Outcome Measures

1. Amount of Slow Wave Activity determines insulin sensitivity. [2 days]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 20 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• healthy volunteers age 18-20 with a BMI < 27kg/m2 in women and < 28 kg/m2 in men with normal findings on clinical examination, routine laboratory tests and EKG

• only subjects who have regular life styles (no shift work, no travel across time zone during the previous 4 weeks)

• habitual bedtimes between 7.0-8.5 hours/night

• do not take medications will be recruited

Exclusion Criteria:

• women taking hormonal contraceptive therapy and pregnant women will be excluded

• individuals with a history of psychiatric, endocrine, cardiac or sleep disorders will be excluded

• other exclusion criteria will be: tobacco use, habitual alcohol use of more than 1 drink per day, excessive caffeine intake of more than 300 mg per day

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Chicago	Chicago	Illinois	United States	60637

Sponsors and Collaborators

• University of Chicago

Investigators

• Principal Investigator: Eve Van Cauter, Ph.D., University of Chicago

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University of Chicago
• ClinicalTrials.gov Identifier: NCT00989378
• Other Study ID Numbers: 16026A
• First Posted: Oct 5, 2009
• Last Update Posted: Sep 5, 2013
• Last Verified: Sep 1, 2013

• Keywords provided by University of Chicago: sleep; insulin; diabetes; determine association between sleep characteristics and diabetes risk
• Additional relevant MeSH terms: Diabetes Mellitus

Study Results

No Results Posted as of Sep 5, 2013