Infantile Hemangioma With Minimal or Arrested Growth : Epidemiology, Clinical Characteristics and Evolution
Study Details
Study Description
Brief Summary
Infantile hemangioma (IH) is the most common vascular tumor of infancy, characterized by its clinical history. Absent at birth or present under the form of a premonitory mark, they display a rapid proliferative phase starting in the first weeks of life. Then, after a plateau phase, they slowly involute. However, a subtype of IH named "abortive", "minimal or arrested growth", "reticular" or "telangiectatic" hemangioma differs from typical IH because it doesn't have a proliferative component, or only a minimal one. This subtype of hemangioma has been recently described and data are lacking regarding its proportion among infantile hemangioma and its differences with "classic" infantile hemangioma. The aim of this study is to estimate the proportion of abortive hemangioma among infantile hemangioma. Also, the investigators aim to compare the clinical characteristics of "classic" infantile hemangiomas and abortive hemangiomas. Lastly, investigators wished to study the evolution of abortive hemangioma.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Infantile hemangioma with minimal or arrested growth Epidemiological and clinical characteristics of infantile hemangioma with minimal or arrested growth. |
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Classic infantile hemangioma Epidemiological and clinical characteristics of classic infantile hemangioma. |
Outcome Measures
Primary Outcome Measures
- Proportion of abortive hemangioma among infantile hemangioma [baseline]
Proportion of abortive hemangioma among infantile hemangioma
Secondary Outcome Measures
- To compare the epidemiological characteristics between infantile hemangioma and abortive hemangioma : sex [baseline]
Compare sex predominance between infantile hemangioma and abortive hemangioma
- To compare the epidemiological characteristics between infantile hemangiomas and abortive hemangiomas : prematurity [baseline]
Compare prematurity rates between infantile hemangiomas and abortive hemangiomas
- To compare the epidemiological characteristics between infantile hemangiomas and abortive hemangiomas : birthweight [baseline]
Compare birthweight between infantile hemangiomas and abortive hemangiomas
- To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : localization [baseline]
Compare localization between infantile hemangiomas and abortive hemangiomas
- To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : treatment [baseline]
le hemangiomas and abortive hemangiomaCompare treatment between infanti
- To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : complications [baseline]
Compare complications between infantile hemangiomas and abortive hemangioma
- To compare the clinical characteristics between infantile hemangiomas and abortive hemangiomas : size [baseline]
Compare size (focal, extended or segmental) between infantile hemangiomas and abortive hemangioma
- To study the evolution of abortive hemangioma : erythematous macule [through study completion, an average of 4 years]
Evaluation of the fading of erythematous macule between the stage of maximal proliferation and the last follow-up
- To study the evolution of abortive hemangioma : papules of proliferation [through study completion, an average of 4 years]
Evaluation of the regression of the papules of proliferation between the stage of maximal proliferation and the last follow-up
- To study the evolution of abortive hemangioma : telangiectasias [through study completion, an average of 4 years]
Evaluation of the fading of telangiectasias between the stage of maximal proliferation and the last follow-up
- To study the evolution of abortive hemangioma : halo of vasoconstriction [through study completion, an average of 4 years]
Evaluation of the fading of the vasoconstricted halo between the stage of maximal proliferation and the last follow-up
- To study the evolution of abortive hemangioma : areas of vasoconstriction [through study completion, an average of 4 years]
Evaluation of the fading of vasoconstricted areas between the stage of maximal proliferation and the last follow-up
- To study the evolution of abortive hemangioma : dilated veins [through study completion, an average of 4 years]
Evaluation of the fading of dilated veins between the stage of maximal proliferation and the last follow-up
Eligibility Criteria
Criteria
Inclusion Criteria:
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Children between 0 and 18 years old
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Followed in the dermatology department of CHRU de Nancy between January 2014 and December 2020
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Presenting with one or more infantile hemangioma
Exclusion Criteria:
- Those whoes guardian does not want his data to be collected in this study
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | CHRU de Nancy | Nancy | Grand-Est | France | 54000 |
Sponsors and Collaborators
- Central Hospital, Nancy, France
Investigators
- Study Director: BURSZTEJN Anne-Claire, MD, PhD, Central Hospital, Nancy, France
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2019PI221