Inflammation and Steatosis: the Role of Alpha-defensin
Sponsor
Hillel Yaffe Medical Center (Other)
Overall Status
Unknown status
CT.gov ID
NCT03358420
Collaborator
(none)
50
1
7
7.2
Study Details
Study Description
Brief Summary
The aim of this study is to examine the correlation between the severity of non-alcoholic steatohepatitis/non alcoholic fatty liver disease (NASH/NAFLD) in naïve and hepatitis C (HCV) positive patients and the amplitude of alpha-defensin immunohistochemical staining in liver biopsy.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
50 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
Inflammation and Steatosis: the Role of Alpha-defensin
Anticipated Study Start Date
:
Dec 1, 2017
Anticipated Primary Completion Date
:
Jul 1, 2018
Anticipated Study Completion Date
:
Jul 1, 2018
Outcome Measures
Primary Outcome Measures
- Amplitude of immunohistochemical stain [Six months]
The amplitude of each slide will be graded from 1-4
Eligibility Criteria
Criteria
Ages Eligible for Study:
15 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Fatty liver disease patients with liver biopsy
Exclusion Criteria:
- None
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hille Yaffe Medical Center | Hadera | Israel | 38100 |
Sponsors and Collaborators
- Hillel Yaffe Medical Center
Investigators
- Study Director: Rami Abu Fanne, MD, Hillel Yaffe Medical Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:
NCT03358420
Other Study ID Numbers:
- HYMC-103-16
First Posted:
Nov 30, 2017
Last Update Posted:
Nov 30, 2017
Last Verified:
Nov 1, 2017
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: