Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.
Study Details
Study Description
Brief Summary
To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
The study is an observational research, which will recruit the community migratory old people and children at school using cluster sampling in Sanya by Sanya Maternal and Child Health Care Hospital (Sanya Women and Children's Hospital). Sanya Central Hospital(Hainan Third People's Hospital) and People's Hospital of Sanya will assist to diagnose old people disease. The data of climate and environment will be obtained from Sanya Meteorological Administration and Sanya Municipal Ecology and Environment Bureau.
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The primary purpose is to investigate the influence of the unique tropical climate and environmental factors on the migratory old people with diseases such as asthma, allergic rhinitis, COPD or atopic dermatitis in Sanya from northern China, and to provide scientific evidence for publicity of the tourism and the health care industry.
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The secondary purpose is to investigate prevalence and risk factors of asthma, allergic rhinitis and atopic dermatitis among children in Sanya, which will provide a base for prevention and control strategies.
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The third purpose is to retrospectively analyze the influence of climate and environmental factors in Sanya on children with asthma, allergic rhinitis and atopic dermatitis in the past decade, and a comparative analysis of the incidence on children in Sanya and Shanghai.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Migratory old people with asthma from northern China in Sanya Migratory old people with asthma from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
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Migratory old people with allergic rhinitis from northern China in Sanya Migratory old people with allergic rhinitis from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Migratory old people with Chronic Obstructive Pulmonary Disease (COPD) from northern China in Sanya Migratory old people with Chronic Obstructive Pulmonary Disease (COPD) from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Migratory old people with atopic dermatitis from northern China in Sanya Migratory old people with atopic dermatitis from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Children with asthma in Sanya Children with asthma have being expousured to tropical climate and environment in Sanya for years. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
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Children with allergic rhinitis in Sanya Children with allergic rhinitis have being expousured to tropical climate and environment in Sanya for years. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Children with atopic dermatitis in Sanya Children with atopic dermatitis have being expousured to tropical climate and environment in Sanya for years. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Children with eczema in Sanya Children with eczema have being expousured to tropical climate and environment in Sanya for years. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Children with urticaria in Sanya Children with urticaria have being expousured to tropical climate and environment in Sanya for years. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Migratory old people with eczema from northern China in Sanya Migratory old people with eczema from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Migratory old people with urticaria from northern China in Sanya Migratory old people with urticaria from northern China in Sanya have being expousured to two different climate and environment from northern China to Sanya for months. |
Other: Climate and environment in Sanya
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
|
Outcome Measures
Primary Outcome Measures
- The difference of migratory old people with asthma, COPD, allergic rhinitis or atopic dermatitis between winter-spring season in tropical Sanya, Hainan Island and summer-autumn season in northeast China. [3 year]
The asthma, COPD, allergic rhinitis or atopic dermatitis will be diagnosed and assessed through history of diseases and questionnaire..
Secondary Outcome Measures
- Asthma control of migratory old people with asthma. [1-3 year]
Quality of life is assessed through questionnaires of "Asthma Control Questionnaire (ACQ) ".
- Asthma life quality of migratory old people with asthma. [1-3 year]
Quality of life is assessed through questionnaires of "Asthma Quality of Life Questionnaire (AQLQ)".
- Lung function of migratory old people with asthma or COPD. [1-3 year]
Lung function is assessed through simple lung function test using spirometry.
- The respiratory function of migratory old people with COPD. [1-3 year]
Lung function is assessed through Saint George Respiratory Questionnaire (SGRQ).
- Allergens will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis. [1-3 year]
Veinal blood was extracted to detect allergens.
- Inflammatory factors will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis. [1-3 year]
Inflammatory factors such as esophageal granulocytes and eosinophils will be detected to assess inflammatory status of the migratory old people.
- The change of asthma incidence rate in migratory old people . [1-3 year]
Diagnosis and severity grading of asthma is based on the "American Thoracic Society" or the "National Heart, Lung, and Blood Institute guidelines."
Eligibility Criteria
Criteria
Inclusion Criteria:
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50-80 years-old migratory people with asthma, allergic rhinitis, COPD or atopic dermatitis from northern China;
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3-12 years-old children in Sanya;
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Agree to participate this study.
Exclusion Criteria:
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Disagree to participate this study;
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Having other respiratory diseases which can influence airflow, such as lung cancer, tuberculosis, pneumonia, bronchiectasis, etc;
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Inability to understand the study procedures or inability/reluctance to answer questionnaire judged by the investigator.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Sanya Women and Children's Hospital, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University | Sanya | Hainan | China |
Sponsors and Collaborators
- Shanghai Jiao Tong University School of Medicine
Investigators
- Principal Investigator: Shijian Liu, Ph.D, Shanghai Children's Medicial Center affiliated Shanghai Jiao Tong University School of Medicine
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- SYFYIRB2022009