Factors Influencing Perioperative Mortality in Type A Acute Aortic Dissections Operated at Dijon University Hospital

Sponsor

Centre Hospitalier La Chartreuse (Other)

Overall Status

Completed

CT.gov ID

NCT04408404

Collaborator

(none)

230

Enrollment

Location

28.8

Actual Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Type A acute aortic dissections are a rare condition whose natural evolution is catastrophic. Global mortality remains high even if it decreased last years. This is probably due to improvement of diagnostic techniques and the evolution of surgical practices. It is however important to have medical data and statistics obtained in past years in order to better understand the factors influencing peroperative mortality and thereby to continue this improvement.

Condition or Disease	Intervention/Treatment	Phase
Aortic Dissection	Procedure: Acute aortic dissection

Study Design

Study Type:

Observational

Actual Enrollment :

230 participants

Observational Model:

Cohort

Time Perspective:

Retrospective

Official Title:

Factors Influencing Perioperative Mortality in Type A Acute Aortic Dissections Operated at Dijon University Hospital

Actual Study Start Date :

Jan 1, 2018

Actual Primary Completion Date :

Jan 1, 2018

Actual Study Completion Date :

May 26, 2020

Arms and Interventions

Arm	Intervention/Treatment
Type A aortic dissection Patient operated for type A acute aortic dissection between 01 January 2007 and 31 December 2017 in Dijon Burgundy University Hospital	Procedure: Acute aortic dissection Acute aortic dissection treatment include Bentall procedure, Tyrone David procedure, Yacoub procedure or ascendant aortic replacement with or without aortic valve replacement, ascendant aortic root remodelling (all are standard of care procedures)

Arm

Intervention/Treatment

Type A aortic dissection

Patient operated for type A acute aortic dissection between 01 January 2007 and 31 December 2017 in Dijon Burgundy University Hospital

Procedure: Acute aortic dissection

Acute aortic dissection treatment include Bentall procedure, Tyrone David procedure, Yacoub procedure or ascendant aortic replacement with or without aortic valve replacement, ascendant aortic root remodelling (all are standard of care procedures)

Outcome Measures

Primary Outcome Measures

Monitor peri-operative mortality incidence rates [1 day]
Mortality during peri-operative acute aortic dissection procedure

Secondary Outcome Measures

Monitor peri-operative morbidity incidence rates [1 day]
Stroke, Kidney failure, Reexploration for bleeding

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 99 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

patients who underwent aortic dissection surgery in Dijon Burgundy University Hospital

Exclusion Criteria:

patients who died before the surgical incision

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Cardiovascular and thoracic surgery Unit - Dijon University Hopital	Dijon		France	21000

Sponsors and Collaborators

Centre Hospitalier La Chartreuse

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

MORGANT Marie-Catherine, Principal investigator, Centre Hospitalier La Chartreuse

ClinicalTrials.gov Identifier:

NCT04408404

Other Study ID Numbers:

CCVT- Dissection

First Posted:

May 29, 2020

Last Update Posted:

May 29, 2020

Last Verified:

May 1, 2020

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Aneurysm, Dissecting

Study Results

No Results Posted as of May 29, 2020