ESTINT: Internalized Stigma in Patients With Bipolar Disorder or Schizophrenia

Sponsor

University of Sao Paulo (Other)

Overall Status

Unknown status

CT.gov ID

NCT01664884

Collaborator

(none)

120

Enrollment

Location

Duration (Months)

17.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this study is to explore the levels of internalized stigma in a sample of young patients with bipolar disorder or schizophrenia.

Condition or Disease	Intervention/Treatment	Phase
Stigma

Detailed Description

The stigma is considered by patients, government organizations and health professionals a key point in mental illness (Griffiths et al, 2006). The related literature has focused on individuals with schizophrenia although there are indications that stigma act negatively in patients with bipolar disorder; this, in turn, is described in a few studies, always with heterogeneous samples, chronic and symptomatic patients (Perlick et al, 2001). It is also known that there is a significant association between affective symptoms and the presence of stigma, (Vázquez et al, 2010).

There are reports of higher levels of public stigma towards people with schizophrenia, compared to patients with bipolar disorder or unipolar depression, however there are no studies available on internalized stigma in such samples, especially in remitted patients . Since schizophrenia coexists with significant impairment of insight, such individuals may exhibit more difficulty internalizing the external bias and stereotypes. On the other hand, patients with bipolar disorder - despite being less discriminated by the public in relation to schizophrenia - probably have a high potential for self-stigma and its fearsome consequences, justified by higher levels of insight.

The investigators would like to examine whether the lower impairment of insight in young bipolar patients(in relation to young people with schizophrenia) could be accompanied by an increase in internalized stigma in this sample. It´s an observational, cross-sectional study with no intervention.

Hypothesis: the internalized stigma in young adults with bipolar disorder is identical to that of young patients with schizophrenia.

Study Design

Study Type:

Observational

Anticipated Enrollment :

120 participants

Observational Model:

Ecologic or Community

Time Perspective:

Cross-Sectional

Official Title:

Internalized Stigma in a Sample of Young Adults With Bipolar Disorder or Schizophrenia.

Study Start Date :

Jun 1, 2012

Anticipated Primary Completion Date :

Jan 1, 2013

Anticipated Study Completion Date :

Jan 1, 2013

Arms and Interventions

Arm	Intervention/Treatment
Bipolar Disorder Patients Bipolar Disorder Patients, with age between 18 to 40 years old, at euthymic phase.
Schizophrenia Patients Schizophrenia Patients, with age between 18 to 40 years old, with minimum or none positive symptoms.

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 40 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Diagnosis of bipolar disorder and schizophrenia according to DSM-IV-TR, presenting in euthymia (bipolar disorder) or without positive symptoms (schizophrenia), based on clinical assessment and confirmed by structured clinical interview SCID-P
Age between 18 and 40 years
Literate and able to understand the tasks required.
Residents of Greater Sao Paulo.
Patients and / or legal representatives must understand the nature of the study and sign an informed consent.

Exclusion Criteria:

Patients with Schizoaffective Disorder or Mental Retardation.
Unstable serious diseases including kidney disease, gastroenterology, respiratory, cardiovascular, endocrine, neurological, immunological or haematological.