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International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01972802
Collaborator
(none)
900
Enrollment
1
Location
47
Duration (Months)
19.2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Our overall objective is to understand the role of lifestyle factors, genetics and HPV infection in the development and prognosis of head and neck cancer particularly in Asia.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    900 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study
    Study Start Date :
    Jan 1, 2011
    Anticipated Primary Completion Date :
    Dec 1, 2014
    Anticipated Study Completion Date :
    Dec 1, 2014

    Outcome Measures

    Primary Outcome Measures

    1. head and neck cancer risk factor [Four years]

      evaluate the association between certain environmental exposures (e.g. cigarette smoking, alcohol drinking, betel nut chewing…) and head and neck cancers,assess the effect of genetic factors, including both SNP and copy number variation (CNV) through analysis of both main effect and gene-gene interaction

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 80 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    Age 18~80 Incident head and neck cancer patients

    • Oral, oropharynx and hypopharynx (C00-C14)

    • Laryngreal cancer (C32)

    • *Esophageal cancer if possible (C15)

    Exclusion Criteria:

    • Salivary gland (C07-C08)

    • Nasopharynx (C11)

    • Thyroid (C79.3)

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Taiwan University Hospital Tiapei Taipei Taiwan 100

    Sponsors and Collaborators

    • National Taiwan University Hospital

    Investigators

    • Principal Investigator: Pei-Jen Lou, National Taiwan University Hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Taiwan University Hospital
    ClinicalTrials.gov Identifier:
    NCT01972802
    Other Study ID Numbers:
    • 201006077R
    First Posted:
    Oct 30, 2013
    Last Update Posted:
    Oct 30, 2013
    Last Verified:
    Oct 1, 2013
    Keywords provided by National Taiwan University Hospital
    HEAD AND NECK
    Additional relevant MeSH terms:
    Head and Neck Neoplasms
    Alcohol Drinking

    Study Results

    No Results Posted as of Oct 30, 2013