International Cooperation for Post-Cherynobyl NIS Thyroid Tissue and Data Banks

Sponsor
National Cancer Institute (NCI) (NIH)
Overall Status
Completed
CT.gov ID
NCT00339274
Collaborator
(none)
4,000
1
149.1
26.8

Study Details

Study Description

Brief Summary

The large number of thyroid tumors that have occurred in areas exposed to high levels of fallout from the Chernobyl accident raise problems of public health importance, or regulatory importance, and of scientific importance. The over-riding priority must go to matters such as diagnosis, treatment of those affected and prevention, and International Agencies are giving financial and material help in these areas. However providing the needs of the patient are not compromised, it is very important to ensure that information that may be of value to the health of future generations is not lost. International agencies are again providing financial support for a variety of joint studies, some of which are based on studies of tissues from thyroid operations carried out as part of treatment, and not required for the initial diagnosis on which treatment is based. An international coordinated approach to this problem is not in place to help Belarus, the Russian Federation and Ukraine to establish their own comprehensive thyroid tissue and data banks and to ensure that tissue and nucleic acids are used to contribute to the understanding of the consequences of the Chernobyl accident. This project has the support of the Governments of Belarus, the Russian Federation and Ukraine and the National Cancer Institute of the USA, (NCI), the European Commission (EC), the Sasakawa Memorial Health Foundation of Japan (SMHF) and the World Health Organization (WHO) have agreed to cooperate in supporting this project.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The large number of thyroid tumors that have occurred in areas exposed to high levels of fallout from the Chernobyl accident raise problems of public health importance, or regulatory importance, and of scientific importance. The over-riding priority must go to matters such as diagnosis, treatment of those affected and prevention, and International Agencies are giving financial and material help in these areas. However providing the needs of the patient are not compromised, it is very important to ensure that information that may be of value to the health of future generations is not lost. International agencies are again providing financial support for a variety of joint studies, some of which are based on studies of tissues from thyroid operations carried out as part of treatment, and not required for the initial diagnosis on which treatment is based. An international coordinated approach to this problem is not in place to help Belarus, the Russian Federation and Ukraine to establish their own comprehensive thyroid tissue and data banks and to ensure that tissue and nucleic acids are used to contribute to the understanding of the consequences of the Chernobyl accident. This project has the support of the Governments of Belarus, the Russian Federation and Ukraine and the National Cancer Institute of the USA, (NCI), the European Commission (EC), the Sasakawa Memorial Health Foundation of Japan (SMHF) and the World Health Organization (WHO) have agreed to cooperate in supporting this project.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    4000 participants
    Official Title:
    The Chernobyl Tissue Bank
    Study Start Date :
    Oct 14, 1999
    Study Completion Date :
    Mar 16, 2012

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      • INCLUSION CRITERIA:

      Patients with thyroid tumours from the whole of Belarus, and the contaminated oblasts of the Russian Federation and Ukraine who were born after 26th April 1967.

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 National Cancer Institute (NCI), 9000 Rockville Pike Bethesda Maryland United States 20892

      Sponsors and Collaborators

      • National Cancer Institute (NCI)

      Investigators

      • Principal Investigator: Louise Brinton, Ph.D., National Cancer Institute (NCI)

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00339274
      Other Study ID Numbers:
      • 999900024
      • OH00-C-N024
      • NCT00897572
      First Posted:
      Jun 21, 2006
      Last Update Posted:
      Jul 2, 2017
      Last Verified:
      Mar 16, 2012
      Keywords provided by , ,

      Study Results

      No Results Posted as of Jul 2, 2017