IMPRESS: International Multicentre Prevalence Study on Sepsis

Sponsor

European Society of Intensive Care Medicine (Other)

Overall Status

Completed

CT.gov ID

NCT01943747

Collaborator

Society of Critical Care Medicine (SCCM) (Other)

1,000

Enrollment

Location

Duration (Months)

499

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

To mark 10 years of the Surviving Sepsis Campaign (SSC), and timed to coincide with World Sepsis Day, on September 13, 2013, the SSC, ESICM and SCCM will be conducting an international point prevalence study of severe sepsis and septic shock. The goal of this project is to determine the world wide burden of severe sepsis and define current practices of sepsis care internationally. The study is a simple data collection exercise for patients presenting with either severe sepsis or septic shock on World Sepsis Day.

Condition or Disease	Intervention/Treatment	Phase
Severe Sepsis Septic Shock

Detailed Description

De---identified patient---level data will be collected on patients presenting to a participating intensive care unit or emergency department with severe sepsis or septic shock over a 24 hour period from 00:00 to 24:00 November 07, 2013. De---identified data that is already collected as part of routine clinical care will be collected for this study. Data to be collected includes hospital and ICU characteristics, patient characteristics, severity of illness, and adherence to SSC bundle elements and mortality. It will take between 30---60 minutes to collect and enter data for each patient admitted with severe sepsis or septic shock over the 24 hours study period.

Study Design

Study Type:

Observational

Anticipated Enrollment :

1000 participants

Observational Model:

Case-Only

Time Perspective:

Prospective

Official Title:

Surviving Sepsis Campaign. International Multicentre Prevalence Study on Sepsis.

Study Start Date :

Nov 1, 2013

Actual Primary Completion Date :

Nov 1, 2013

Actual Study Completion Date :

Jan 1, 2014

Outcome Measures

Primary Outcome Measures

28-Day Mortality [one week]

Secondary Outcome Measures

Organ Failure [one week]

Other Outcome Measures

Length of Stay in the Hospital [one week]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

To be eligible patients must have all of the following:

Must be admitted or transferred to either the ED or an Intensive Care Unit.
Have a high clinical suspicion of an infection
Have sepsis as defined by an infection together with two or more SIRS criteria
Evidence of acute organ dysfunction and/or Shock.

Exclusion Criteria:

Patients less than 18 years of age
Patients in whom the sepsis has been present from before the beginning of the study period
Any patients previously included in the study during the same study period