HIT in the Healthy Elderly Population

• Sponsor: University of Nottingham (Other)
• Overall Status: Completed
• CT.gov ID: NCT02167191
• Collaborator: (none)
• Enrollment: 24
• Location: 1
• Arm: 1
• Duration (Months): 5.9
• Patients Per Site Per Month: 4

Study Details

Study Description

Brief Summary

It is widely known that exercise improves general fitness and that fitter patients recover more easily from illness and surgery. Conversely, unfit patients have a significantly higher morbidity and mortality after surgery and a longer inpatient stay. This will become increasingly important in an aging population as baseline fitness generally declines with age.

One method of improving cardiovascular fitness is by using low intensity endurance training programmes, a disadvantage of these it that they can take several months to show improvement. High intensity interval training (HIT) programmes that use short episodes of high intensity exercise have also been shown to improve fitness. These HIT programmes have also shown improvement in functional capacity and quality of life in patients with chronic disease. An advantage of HIT is that improvements in fitness may occur in a shorter time than traditional endurance training. It is also known that HIT can give superior gains over endurance training.

The primary aim of this study is to determine whether an improvement in aerobic fitness, as judged by a 2ml/kg/min increase in VO2peak, can be achieved within 31 days via a HIT programme, in a group of healthy elderly volunteers.

As a secondary aim we will assess whether this programme would be acceptable to the group studied, through determination of subject compliance and adherence to the training programme.

Condition or Disease	Intervention/Treatment	Phase
Interval Training; Pre Operative Exercise; Prehabilitation; Elderly	Behavioral: HIT	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 24 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: Determining the Effectiveness of a High Intensity Interval Training Exercise Programme in the Healthy, Elderly Population
• Study Start Date: Feb 1, 2014
• Actual Primary Completion Date: Jul 1, 2014
• Actual Study Completion Date: Aug 1, 2014

Arms and Interventions

Arm	Intervention/Treatment
Experimental: HIT High intensity interval training sessions on an cycle ergometer	Behavioral: HIT; 12 sessions of HIT exercise in 31 days on a stationary cycle ergometer

Outcome Measures

Primary Outcome Measures

1. VO2 peak [31 days]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 60 Years to 75 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Good health

• Male and female

• 60 -75 years old

Exclusion Criteria:

• Uncontrolled hypertension (BP > 140/100)

• Angina

• Heart failure (NYHA class III/IV)

• Cardiac arrthymias

• Right to left cardiac shunt

• Recent cardiac event

• Previous stroke/TIA

• Aneurysm (large vessel or intracranial)

• Severe respiratory disease including pulmonary hypertension

• COPD/asthma with an FEV1 less than 1.5 l

• Inclusion into any other research study in the last three months which involved: taking a drug; being paid a disturbance allowance; having an invasive procedure or exposure to ionising radiation

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Nottingham	Derby	Derbyshire	United Kingdom	DE22 3DT

Sponsors and Collaborators

• University of Nottingham

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University of Nottingham
• ClinicalTrials.gov Identifier: NCT02167191
• Other Study ID Numbers: HIT
• First Posted: Jun 18, 2014
• Last Update Posted: Oct 1, 2015
• Last Verified: Sep 1, 2015

Study Results

No Results Posted as of Oct 1, 2015