Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
Study Details
Study Description
Brief Summary
This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma that is growing, spreading, or getting worse (progressive). Vismodegib, FAK inhibitor GSK2256098, capivasertib, and abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 2 |
Detailed Description
PRIMARY OBJECTIVES:
-
To determine the activity of a SMO inhibitor in patients with meningiomas harboring SMO and PTCH1 mutations as measured by 6-month progression free survival (PFS) and response rate.
-
To determine the activity of a FAK inhibitor in patients with meningiomas harboring NF2 mutations as measured by 6-month PFS and response rate.
-
To determine the activity of an AKT inhibitor in patients with meningiomas harboring AKT1/PIK3CA/PTEN mutations as measured by 6-month PFS and response rate.
-
To determine the activity of a CDK inhibitor in patients with meningiomas harboring alterations in the CDK pathway or NF2 alterations as measured by 6-month PFS and response rate.
SECONDARY OBJECTIVES:
-
To determine overall survival and progression-free survival of SMO, FAK, AKT and CDK inhibitors in patients with meningioma.
-
To determine adverse event rates of SMO, FAK, AKT and CDK inhibitors in patients with meningioma.
-
To determine the activity of SMO, FAK, AKT and CDK inhibitors as measured by response rate by central radiology review.
OUTLINE: Patients are assigned to 1 of 4 treatment arms based on their mutation status.
ARM A (SMO/PTCH1 mutation): Patients receive vismodegib orally (PO) once daily (QD). Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. (CLOSED TO ACCRUAL FEBRUARY 2018)
ARM B (NF2 mutation): Patients receive FAK inhibitor GSK2256098 PO twice daily (BID). Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. (CLOSED TO ACCRUAL JULY 2017)
ARM C (AKT1, PIK3CA, or PTEN mutation): Patients receive capivasertib PO BID on days 1-4. Treatment repeats every 7 days for up to 1 cycle (28 days) in the absence of disease progression or unacceptable toxicity.
ARM D (CDK4, CDK6, CDKN2A, CCND1, CCND2, CCND3, CCNE1 alterations): Patients receive abemaciclib PO every 12 hours (Q12H). Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed up every 6 months for a maximum of 5 years from registration.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Arm A (vismodegib) Patients receive vismodegib PO QD. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. (CLOSED TO ACCRUAL FEBRUARY 2018) |
Drug: Vismodegib
Given PO
Other Names:
|
| Experimental: Arm B (FAK inhibitor GSK2256098) Patients receive FAK inhibitor GSK2256098 PO BID. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. (CLOSED TO ACCRUAL JULY 2017) |
Drug: FAK Inhibitor GSK2256098
Given PO
|
| Experimental: Arm C (capivasertib) Patients receive capivasertib PO BID on days 1-4. Treatment repeats every 7 days for up to 1 cycle (28 days) in the absence of disease progression or unacceptable toxicity. |
Drug: Capivasertib
Given PO
Other Names:
|
| Experimental: Arm D (abemaciclib) Patients receive abemaciclib PO Q12H. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. |
Drug: Abemaciclib
Given PO
|
Outcome Measures
Primary Outcome Measures
- Progression free survival (PFS) [At 6 months]
Point estimates and 95% binomial confidence intervals will be generated for the six month PFS rate within each cohort of each treatment arm. Kaplan-Meier curves will be generated for PFS for each cohort within each treatment arm.
- Response rate defined as a confirmed complete response (CR) or partial response (PR) [Up to 2 years]
Point estimates will be generated for response rates within each treatment arm with corresponding 95% binomial confidence intervals.
Secondary Outcome Measures
- Overall survival (OS) [Up to 2 years]
OS will be summarized for each cohort within each treatment group with Kaplan-Meier curves and estimates.
- Incidence of adverse events according to National Cancer Institute CTCAE version 4.0 [Up to 4 weeks after completion of study treatment]
Adverse events (AEs) will be summarized for each treatment group. They will be summarized as the number and frequency of each event. In addition the AEs will be summarized as the number and frequency of patients who experience any AE, AEs of grade 3+, and AEs of grade 4+.
Eligibility Criteria
Criteria
-
Documentation of disease:
-
Histologic documentation: histologically proven intracranial meningioma as documented by central pathology review
-
Molecular documentation: Presence of SMO, PTCH1, NF2, CDKN2A, AKT1, PIK3CA, PTEN mutations, CDKN2A copy number loss, CDK4, CDK6, CCND1, CCND2, CCND3, or CCNE1 copy number gain in tumor sample as documented specifically by the central laboratory, regardless of whether prior genotype testing outside of the central laboratory was performed
-
Progressive OR residual disease, as defined by the following:
-
Residual measurable disease: residual measurable disease immediately after surgery without requirement for progression; for grade I disease, progression pre-operatively needs to be documented, with an increase in size of the measurable primary lesion on imaging by 25% or more (bidirectional area); the change must occur between scans separated by no more than 25 months; for patients with SMO/PTCH1 mutations enrolling to receive vismodegib, the change can occur between scans separated by up to 25 months; residual measurable disease will be defined by bidimensionally measurable lesions with clearly defined margins by MRI scans, with a minimum diameter of 10 mm in both dimensions
-
Progressive measurable disease: progression defined as an increase in size of the measurable primary lesion on imaging by 25% or more (bidirectional area); the change must occur between scans separated by no more than 25 months
-
Post radiation patients: patients with measurable and progressive meningioma who have received radiation are potentially eligible, but need to show evidence of progressive disease after completion of radiation; if the progressive meningioma lesion has been radiated, at least 24 weeks must have elapsed from completion of radiation to registration; if the progressive lesion is outside of the radiation field, then an interval of at least 2 weeks must have elapsed from completion of radiation to registration
-
Measurable disease: measurable disease is defined by a bidimensionally measurable main lesion on MRI or computed tomography (CT) images (MRI preferred) with clearly defined margins and a minimum diameter of 10 mm in both dimensions; multifocal disease is allowed
-
Prior treatment
-
Prior medical therapy is allowed but not required
-
No limit on number of prior therapies
-
No chemotherapy, or other investigational agents within 28 days prior to registration
-
No other concurrent investigational agents or other meningioma-directed therapy (chemotherapy, radiation) while on study; additionally, no cases of nitrosourea or mitomycin C within 6 weeks prior to registration
-
For patients treated with external beam radiation, interstitial brachytherapy or radiosurgery, an interval > 4 weeks must have elapsed from completion of radiation therapy to registration; if the progressive lesion is outside of the radiation field, then an interval of at least 2 weeks must have elapsed from completion of radiation to registration
-
Steroid dosing stable for at least 4 days
-
Recovered to Common Terminology Criteria for Adverse Events (CTCAE) grade 1 or less toxicity from other agents with exception of alopecia and fatigue
-
No craniotomy 28 days prior to and after registration
-
Not pregnant and not nursing:
- A female of childbearing potential is a sexually mature female who: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 12 consecutive months (i.e., has had menses at any time in the preceding 12 consecutive months)
-
For patients with NF2/CDKN2A/AKT1/PIK3CA/PTEN mutation, CKDN2A copy number loss, or CDK4/CDK6/CCND1/CCND2/CCND3/CCNE1 copy number gain: Age >= 18 years
-
For patients with SMO/PTCH1 mutation: Age >= 30 years
-
Eastern Cooperative Oncology Group (ECOG) performance status =< 2
-
Patient history:
-
Patients with history of neurofibromatosis (NF) may have other stable central nervous system (CNS) tumors (schwannoma, acoustic neuroma or ependymoma) if lesions have been stable for 6 months
-
No metastatic meningiomas (as defined by extracranial meningiomas outside of CNS) allowed; spinal meningiomas are allowed
-
No history of allergic reactions attributed to compounds of similar or biologic composition to assigned study drug
-
No known active hepatitis B or C
-
No current Child Pugh class B or C liver disease
-
No uncontrolled gastric ulcer disease (grade 3 gastric ulcer disease within 28 days of registration)
-
No uncontrolled hypertension defined as blood pressure (BP) > 140/90
-
No abdominal fistula, gastrointestinal (GI) perforation, or intra-abdominal abscess within 28 days prior to registration
-
No major surgery within 28 days prior to registration for any patients with AKT1/PIK3CA/PTEN mutations receiving capivasertib
-
For patients going on to receive capivasertib (i.e. enrolled after Update #08)
-
Patients should not have any of the following cardiac criteria:
-
Any clinically important abnormalities in rhythm, conduction, or morphology of resting electrocardiogram (EKG) (e.g., complete left bundle branch block, third degree heart block)
-
Any factors that increase the risk of corrected QT (QTc) prolongation or risk of arrhythmic events such as heart failure, hypokalemia, potential for Torsade de Pointes, congenital long QT syndrome, family history of long QT syndrome, or unexplained sudden death under 40 years of age, or any concomitant medication known to prolong the QT interval
-
Experience any of the following procedures or conditions in the preceding 6 months: coronary artery bypass graft, angioplasty, vascular stent, myocardial infarction, angina pectoris, congestive heart failure New York Heart Association (NYHA) class >= II
-
Uncontrolled hypertension (systolic blood pressure [SBP] < 90 mmHg and/or diastolic blood pressure [DBP] < 50 mmHg)
-
Cardiac ejection fraction outside institutional range of normal or < 50% (whichever is higher) as measured by echocardiogram (or multigated acquisition [MUGA] scan if an echocardiogram can't be performed or is inconclusive); left ventricular ejection fraction (LVEF) below lower limit of normal for site
-
Patients should not have any of the following criteria:
-
With the exception of alopecia, any unresolved toxicities from prior therapy greater than Common Terminology Criteria for Adverse Events (CTCAE) grade 1 at the time of registration
-
Hemoglobin < 9 g/dL (< 5.59 mmol/L); note: any blood transfusion must be >= 14 days prior to the determination of a hemoglobin >= 9 g/dL (>= 5.59 mmol/L)
-
Proteinuria 3+ on dipstick analysis or > 500 mg/24 hours
-
Refractory nausea and vomiting, chronic gastrointestinal diseases, inability to swallow the formulated product or previous significant bowel resection that would preclude adequate absorption of capivasertib
-
History of hypersensitivity to active or inactive excipients of capivasertib or drugs with a similar chemical structure or class to capivasertib
-
Current disease or condition known to interfere with absorption, distribution, metabolism, or excretion of drugs
-
Past medical history of interstitial lung disease, drug-induced interstitial lung disease, radiation pneumonitis which required steroid treatment, or any evidence of clinically active interstitial lung disease
-
Previous allogeneic bone marrow transplant
-
Known immunodeficiency syndrome
-
Concomitant medications (only regarding
NF2/CDKN2A/CDK4/CDK6/CCND1/CCND2/CCND3/CCNE1/AKT1/PIK3CA/PTEN genetic alterations):
-
Chronic concomitant treatment with strong inhibitors of cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) inhibitors must discontinue the drug for 14 days prior to registration on the study for patients with NF2 mutation enrolled to GSK2256098, as well as for patients with AKT1/PIK3CA/PTEN mutations enrolled to capivasertib
-
For NF2 patients going on to receive GSK2256098 and for patients with AKT1/PIK3CA/PTEN mutations enrolled to capivasertib: concomitant treatment with strong CYP3A4 inducers or CYP2D6 substrates is not allowed; patients must discontinue the drug 14 days prior to registration
-
For NF2 patients going on to receive abemaciclib: avoid concomitant use of CYP3A inducers and strong CYP3A inhibitors; use caution with coadministered moderate or weak CYP3A inhibitors
-
Diabetic status:
-
For patients with NF2 or SMO/PTCH1 mutations: No uncontrolled diabetes defined as a known diabetic with HBA1C > 7.5 OR fasting glucose > 140 mg/dL.
-
For patients with AKT1/PIK3CA/PTEN mutations:
-
Glycosylated hemoglobin (HbA1C) < 8.0% (63.9 mmol/mol)
-
No type 1 diabetes mellitus
-
No requirement for insulin for routine diabetic management and control
-
No requirement for more than two oral hypoglycemic medications for routine diabetic management and control
-
Patients with a pre-existing diagnosis of type 2 diabetes mellitus must have fasting glucose < 9.3 mmol/L (167mg/dL); fasting is defined as no caloric intake for at least 8 hours
-
Patients without a pre-existing diagnosis of type 2 diabetes mellitus must have fasting glucose =< 7.0 mmol/L (126 mg/dL); fasting is defined as no caloric intake for at least 8 hours
-
Absolute neutrophil count (ANC) >= 1,500/mm^3
-
Platelet count >= 100,000/mm^3
-
Creatinine OR =< 1.5 mg/dl x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 50 mL/min
-
Urine protein:creatinine ratio (UPC) =< 45 mg/mmol
-
Total bilirubin =< 1.5 x upper limit of normal (ULN); except in case of Gilbert's disease
-
Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x ULN
-
Sodium, potassium, total calcium (corrected for serum albumin) & phosphorus within normal limits per institutional guidelines
-
QTcF < 450 msec (QT calculated using Fridericia formula)
-
Mean resting heart rate (determined from EKG) 50-100 beats per minute (BMP) (must be obtained from 12-lead EKG defined by a triplicate EKG for patients assigned to the capivasertib arm; patients assigned to all other arms will require a single EKG
-
No uncontrolled medical comorbidities per investigator discretion (e.g. interstitial lung disease, severe dyspnea at rest or requiring oxygen therapy, history of major surgical resection involving the stomach or small bowel, or pre-existing Crohn's disease or ulcerative colitis or a preexisting chronic condition resulting in baseline Grade 2 or higher diarrhea)
-
ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: Hemoglobin >= 8 g/dL
- Patients may receive erythrocyte transfusions to achieve this hemoglobin level at the discretion of the investigator; initial treatment must not begin earlier than the day after the erythrocyte transfusion
-
ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: Prior Treatment
-
Patients who received chemotherapy must have recovered (Common Terminology Criteria for Adverse Events [CTCAE] grade =< 1) from the acute effects of chemotherapy except for residual alopecia or grade 2 peripheral neuropathy prior to registration; a washout period of at least 28 days is required between last chemotherapy dose and registration (provided the patient did not receive radiotherapy)
-
Patients who received adjuvant radiotherapy must have completed and fully recovered from the acute effects of radiotherapy; a washout period of at least 28 days is required between end of radiotherapy and registration
-
ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: No active bacterial infection (requiring intravenous [IV] antibiotics at time of initiating study treatment), fungal infection, or detectable viral infection (such as known human immunodeficiency virus positivity or with known active hepatitis B or C [for example, hepatitis B surface antigen positive]); screening is not required for enrollment in the absence of symptoms
-
ADDITIONAL REGISTRATION ELIGIBILITY CRITERIA FOR ABEMACICLIB ARM: No personal history of any of the following conditions: syncope of cardiovascular etiology, ventricular arrhythmia of pathological origin (including, but not limited to, ventricular tachycardia and ventricular fibrillation), or sudden cardiac arrest
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | United States | 35233 |
| 2 | Anchorage Associates in Radiation Medicine | Anchorage | Alaska | United States | 98508 |
| 3 | Anchorage Radiation Therapy Center | Anchorage | Alaska | United States | 99504 |
| 4 | Alaska Breast Care and Surgery LLC | Anchorage | Alaska | United States | 99508 |
| 5 | Alaska Oncology and Hematology LLC | Anchorage | Alaska | United States | 99508 |
| 6 | Alaska Women's Cancer Care | Anchorage | Alaska | United States | 99508 |
| 7 | Anchorage Oncology Centre | Anchorage | Alaska | United States | 99508 |
| 8 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
| 9 | Providence Alaska Medical Center | Anchorage | Alaska | United States | 99508 |
| 10 | Kingman Regional Medical Center | Kingman | Arizona | United States | 86401 |
| 11 | Cancer Center at Saint Joseph's | Phoenix | Arizona | United States | 85004 |
| 12 | Saint Joseph's Hospital and Medical Center | Phoenix | Arizona | United States | 85013 |
| 13 | Mayo Clinic in Arizona | Scottsdale | Arizona | United States | 85259 |
| 14 | Arizona Oncology Services Foundation | Scottsdale | Arizona | United States | 85260 |
| 15 | Mercy Hospital Fort Smith | Fort Smith | Arkansas | United States | 72903 |
| 16 | CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | United States | 71913 |
| 17 | Kaiser Permanente-Deer Valley Medical Center | Antioch | California | United States | 94531 |
| 18 | Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande | California | United States | 93420 |
| 19 | PCR Oncology | Arroyo Grande | California | United States | 93420 |
| 20 | Sutter Auburn Faith Hospital | Auburn | California | United States | 95602 |
| 21 | Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | United States | 95603 |
| 22 | Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | United States | 94704 |
| 23 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
| 24 | Mills-Peninsula Medical Center | Burlingame | California | United States | 94010 |
| 25 | Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | United States | 95682 |
| 26 | Eden Hospital Medical Center | Castro Valley | California | United States | 94546 |
| 27 | Sutter Davis Hospital | Davis | California | United States | 95616 |
| 28 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
| 29 | Palo Alto Medical Foundation-Fremont | Fremont | California | United States | 94538 |
| 30 | Kaiser Permanente-Fresno | Fresno | California | United States | 93720 |
| 31 | UC San Diego Moores Cancer Center | La Jolla | California | United States | 92093 |
| 32 | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | United States | 90027 |
| 33 | Los Angeles County-USC Medical Center | Los Angeles | California | United States | 90033 |
| 34 | USC / Norris Comprehensive Cancer Center | Los Angeles | California | United States | 90033 |
| 35 | Memorial Medical Center | Modesto | California | United States | 95355 |
| 36 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
| 37 | Palo Alto Medical Foundation-Camino Division | Mountain View | California | United States | 94040 |
| 38 | Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California | United States | 94040 |
| 39 | USC Norris Oncology/Hematology-Newport Beach | Newport Beach | California | United States | 92663 |
| 40 | Sutter Cancer Research Consortium | Novato | California | United States | 94945 |
| 41 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
| 42 | UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | United States | 92868 |
| 43 | Palo Alto Medical Foundation Health Care | Palo Alto | California | United States | 94301 |
| 44 | Keck Medical Center of USC Pasadena | Pasadena | California | United States | 91105 |
| 45 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
| 46 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
| 47 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
| 48 | Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | United States | 95661 |
| 49 | Sutter Roseville Medical Center | Roseville | California | United States | 95661 |
| 50 | Sutter Medical Center Sacramento | Sacramento | California | United States | 95816 |
| 51 | University of California Davis Comprehensive Cancer Center | Sacramento | California | United States | 95817 |
| 52 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
| 53 | Kaiser Permanente - Sacramento | Sacramento | California | United States | 95825 |
| 54 | California Pacific Medical Center-Pacific Campus | San Francisco | California | United States | 94115 |
| 55 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
| 56 | UCSF Medical Center-Parnassus | San Francisco | California | United States | 94143 |
| 57 | UCSF Medical Center-Mission Bay | San Francisco | California | United States | 94158 |
| 58 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
| 59 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
| 60 | Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | United States | 93401 |
| 61 | Mills Health Center | San Mateo | California | United States | 94401 |
| 62 | Kaiser Permanente-San Rafael | San Rafael | California | United States | 94903 |
| 63 | Kaiser San Rafael-Gallinas | San Rafael | California | United States | 94903 |
| 64 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
| 65 | Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California | United States | 95065 |
| 66 | Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | United States | 93444 |
| 67 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
| 68 | Sutter Pacific Medical Foundation | Santa Rosa | California | United States | 95403 |
| 69 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
| 70 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
| 71 | Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | United States | 94086 |
| 72 | Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | United States | 95687 |
| 73 | Kaiser Permanente Medical Center-Vacaville | Vacaville | California | United States | 95688 |
| 74 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
| 75 | Sutter Solano Medical Center/Cancer Center | Vallejo | California | United States | 94589 |
| 76 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
| 77 | University of Colorado Hospital | Aurora | Colorado | United States | 80045 |
| 78 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
| 79 | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | United States | 80907 |
| 80 | Saint Francis Cancer Center | Colorado Springs | Colorado | United States | 80923 |
| 81 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
| 82 | Mercy Medical Center | Durango | Colorado | United States | 81301 |
| 83 | Southwest Oncology PC | Durango | Colorado | United States | 81301 |
| 84 | Mountain Blue Cancer Care Center | Golden | Colorado | United States | 80401 |
| 85 | Grand Valley Oncology | Grand Junction | Colorado | United States | 81505 |
| 86 | Rocky Mountain Cancer Centers-Lakewood | Lakewood | Colorado | United States | 80228 |
| 87 | Saint Anthony Hospital | Lakewood | Colorado | United States | 80228 |
| 88 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
| 89 | Longmont United Hospital | Longmont | Colorado | United States | 80501 |
| 90 | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | United States | 80501 |
| 91 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
| 92 | Rocky Mountain Cancer Centers-Parker | Parker | Colorado | United States | 80138 |
| 93 | Saint Mary Corwin Medical Center | Pueblo | Colorado | United States | 81004 |
| 94 | Rocky Mountain Cancer Centers - Pueblo | Pueblo | Colorado | United States | 81008 |
| 95 | Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado | United States | 80260 |
| 96 | Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut | United States | 06105 |
| 97 | Yale University | New Haven | Connecticut | United States | 06520 |
| 98 | Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut | United States | 06611 |
| 99 | Mount Sinai Comprehensive Cancer Center at Aventura | Aventura | Florida | United States | 33180 |
| 100 | Boca Raton Regional Hospital | Boca Raton | Florida | United States | 33486 |
| 101 | UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | United States | 33442 |
| 102 | Holy Cross Hospital | Fort Lauderdale | Florida | United States | 33308 |
| 103 | University of Florida Health Science Center - Gainesville | Gainesville | Florida | United States | 32610 |
| 104 | Mayo Clinic in Florida | Jacksonville | Florida | United States | 32224-9980 |
| 105 | Mount Sinai Medical Center | Miami Beach | Florida | United States | 33140 |
| 106 | University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | United States | 33136 |
| 107 | UM Sylvester Comprehensive Cancer Center at Plantation | Plantation | Florida | United States | 33324 |
| 108 | Moffitt Cancer Center | Tampa | Florida | United States | 33612 |
| 109 | Emory University Hospital Midtown | Atlanta | Georgia | United States | 30308 |
| 110 | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
| 111 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
| 112 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
| 113 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
| 114 | Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | United States | 83605 |
| 115 | Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | United States | 83814 |
| 116 | Walter Knox Memorial Hospital | Emmett | Idaho | United States | 83617 |
| 117 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
| 118 | Idaho Urologic Institute-Meridian | Meridian | Idaho | United States | 83642 |
| 119 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
| 120 | Saint Alphonsus Medical Center-Nampa | Nampa | Idaho | United States | 83686 |
| 121 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
| 122 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
| 123 | Kootenai Cancer Clinic | Sandpoint | Idaho | United States | 83864 |
| 124 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
| 125 | Saint Anthony's Health | Alton | Illinois | United States | 62002 |
| 126 | Rush - Copley Medical Center | Aurora | Illinois | United States | 60504 |
| 127 | Saint Joseph Medical Center | Bloomington | Illinois | United States | 61701 |
| 128 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
| 129 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
| 130 | Memorial Hospital of Carbondale | Carbondale | Illinois | United States | 62902 |
| 131 | SIH Cancer Institute | Carterville | Illinois | United States | 62918 |
| 132 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
| 133 | Centralia Oncology Clinic | Centralia | Illinois | United States | 62801 |
| 134 | Northwestern University | Chicago | Illinois | United States | 60611 |
| 135 | Rush University Medical Center | Chicago | Illinois | United States | 60612 |
| 136 | University of Illinois | Chicago | Illinois | United States | 60612 |
| 137 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
| 138 | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | United States | 62526 |
| 139 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
| 140 | Illinois CancerCare-Dixon | Dixon | Illinois | United States | 61021 |
| 141 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
| 142 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
| 143 | Illinois CancerCare-Eureka | Eureka | Illinois | United States | 61530 |
| 144 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
| 145 | Western Illinois Cancer Treatment Center | Galesburg | Illinois | United States | 61401 |
| 146 | Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | United States | 60134 |
| 147 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
| 148 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
| 149 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
| 150 | Good Samaritan Regional Health Center | Mount Vernon | Illinois | United States | 62864 |
| 151 | Cancer Care Center of O'Fallon | O'Fallon | Illinois | United States | 62269 |
| 152 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
| 153 | Radiation Oncology of Northern Illinois | Ottawa | Illinois | United States | 61350 |
| 154 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
| 155 | OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center | Pekin | Illinois | United States | 61554 |
| 156 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
| 157 | OSF Saint Francis Radiation Oncology at Peoria Cancer Center | Peoria | Illinois | United States | 61615 |
| 158 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
| 159 | OSF Saint Francis Medical Center | Peoria | Illinois | United States | 61637 |
| 160 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
| 161 | Valley Radiation Oncology | Peru | Illinois | United States | 61354 |
| 162 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
| 163 | Central Illinois Hematology Oncology Center | Springfield | Illinois | United States | 62702 |
| 164 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62702 |
| 165 | Springfield Clinic | Springfield | Illinois | United States | 62702 |
| 166 | Memorial Medical Center | Springfield | Illinois | United States | 62781 |
| 167 | Southwest Illinois Health Services LLP | Swansea | Illinois | United States | 62226 |
| 168 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
| 169 | The Carle Foundation Hospital | Urbana | Illinois | United States | 61801 |
| 170 | Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | United States | 60555 |
| 171 | Illinois CancerCare - Washington | Washington | Illinois | United States | 61571 |
| 172 | Rush-Copley Healthcare Center | Yorkville | Illinois | United States | 60560 |
| 173 | Memorial Regional Cancer Center Day Road | Mishawaka | Indiana | United States | 46545 |
| 174 | Reid Health | Richmond | Indiana | United States | 47374 |
| 175 | Memorial Hospital of South Bend | South Bend | Indiana | United States | 46601 |
| 176 | Mary Greeley Medical Center | Ames | Iowa | United States | 50010 |
| 177 | McFarland Clinic PC - Ames | Ames | Iowa | United States | 50010 |
| 178 | McFarland Clinic PC-Boone | Boone | Iowa | United States | 50036 |
| 179 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
| 180 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
| 181 | Alegent Health Mercy Hospital | Council Bluffs | Iowa | United States | 51503 |
| 182 | Greater Regional Medical Center | Creston | Iowa | United States | 50801 |
| 183 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
| 184 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
| 185 | McFarland Clinic PC-Trinity Cancer Center | Fort Dodge | Iowa | United States | 50501 |
| 186 | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | United States | 52242 |
| 187 | McFarland Clinic PC-Jefferson | Jefferson | Iowa | United States | 50129 |
| 188 | McFarland Clinic PC-Marshalltown | Marshalltown | Iowa | United States | 50158 |
| 189 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
| 190 | Cancer Center of Kansas - Chanute | Chanute | Kansas | United States | 66720 |
| 191 | Cancer Center of Kansas - Dodge City | Dodge City | Kansas | United States | 67801 |
| 192 | Cancer Center of Kansas - El Dorado | El Dorado | Kansas | United States | 67042 |
| 193 | Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | United States | 66701 |
| 194 | Central Care Cancer Center - Great Bend | Great Bend | Kansas | United States | 67530 |
| 195 | Cancer Center of Kansas-Independence | Independence | Kansas | United States | 67301 |
| 196 | Cancer Center of Kansas-Kingman | Kingman | Kansas | United States | 67068 |
| 197 | Lawrence Memorial Hospital | Lawrence | Kansas | United States | 66044 |
| 198 | Kansas Institute of Medicine Cancer and Blood Center | Lenexa | Kansas | United States | 66219 |
| 199 | Minimally Invasive Surgery Hospital | Lenexa | Kansas | United States | 66219 |
| 200 | Cancer Center of Kansas-Liberal | Liberal | Kansas | United States | 67905 |
| 201 | Cancer Center of Kansas-Manhattan | Manhattan | Kansas | United States | 66502 |
| 202 | Cancer Center of Kansas - McPherson | McPherson | Kansas | United States | 67460 |
| 203 | Cancer Center of Kansas - Newton | Newton | Kansas | United States | 67114 |
| 204 | Menorah Medical Center | Overland Park | Kansas | United States | 66209 |
| 205 | Saint Luke's South Hospital | Overland Park | Kansas | United States | 66213 |
| 206 | Cancer Center of Kansas - Parsons | Parsons | Kansas | United States | 67357 |
| 207 | Cancer Center of Kansas - Pratt | Pratt | Kansas | United States | 67124 |
| 208 | Cancer Center of Kansas - Salina | Salina | Kansas | United States | 67401 |
| 209 | Cancer Center of Kansas - Wellington | Wellington | Kansas | United States | 67152 |
| 210 | Associates In Womens Health | Wichita | Kansas | United States | 67208 |
| 211 | Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | United States | 67208 |
| 212 | Ascension Via Christi Hospitals Wichita | Wichita | Kansas | United States | 67214 |
| 213 | Cancer Center of Kansas - Wichita | Wichita | Kansas | United States | 67214 |
| 214 | Cancer Center of Kansas - Winfield | Winfield | Kansas | United States | 67156 |
| 215 | Flaget Memorial Hospital | Bardstown | Kentucky | United States | 40004 |
| 216 | Commonwealth Cancer Center-Corbin | Corbin | Kentucky | United States | 40701 |
| 217 | Oncology Hematology Care Inc-Crestview | Crestview Hills | Kentucky | United States | 41017 |
| 218 | Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | United States | 40504 |
| 219 | Saint Joseph Hospital East | Lexington | Kentucky | United States | 40509 |
| 220 | University of Kentucky/Markey Cancer Center | Lexington | Kentucky | United States | 40536 |
| 221 | Saint Joseph London | London | Kentucky | United States | 40741 |
| 222 | Jewish Hospital | Louisville | Kentucky | United States | 40202 |
| 223 | Saints Mary and Elizabeth Hospital | Louisville | Kentucky | United States | 40215 |
| 224 | UofL Health Medical Center Northeast | Louisville | Kentucky | United States | 40245 |
| 225 | Jewish Hospital Medical Center South | Shepherdsville | Kentucky | United States | 40165 |
| 226 | West Jefferson Medical Center | Marrero | Louisiana | United States | 70072 |
| 227 | Louisiana State University Health Science Center | New Orleans | Louisiana | United States | 70112 |
| 228 | University Medical Center New Orleans | New Orleans | Louisiana | United States | 70112 |
| 229 | University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | United States | 21201 |
| 230 | Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | United States | 21287 |
| 231 | Tufts Medical Center | Boston | Massachusetts | United States | 02111 |
| 232 | Massachusetts General Hospital Cancer Center | Boston | Massachusetts | United States | 02114 |
| 233 | Dana-Farber Cancer Institute | Boston | Massachusetts | United States | 02215 |
| 234 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106 |
| 235 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
| 236 | Saint Joseph Mercy Brighton | Brighton | Michigan | United States | 48114 |
| 237 | Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | United States | 48114 |
| 238 | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | United States | 48183 |
| 239 | Saint Joseph Mercy Canton | Canton | Michigan | United States | 48188 |
| 240 | Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | United States | 48188 |
| 241 | Caro Cancer Center | Caro | Michigan | United States | 48723 |
| 242 | Saint Joseph Mercy Chelsea | Chelsea | Michigan | United States | 48118 |
| 243 | Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | United States | 48118 |
| 244 | Hematology Oncology Consultants-Clarkston | Clarkston | Michigan | United States | 48346 |
| 245 | Newland Medical Associates-Clarkston | Clarkston | Michigan | United States | 48346 |
| 246 | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | United States | 48038 |
| 247 | Beaumont Hospital - Dearborn | Dearborn | Michigan | United States | 48124 |
| 248 | Henry Ford Medical Center-Fairlane | Dearborn | Michigan | United States | 48126 |
| 249 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
| 250 | Ascension Saint John Hospital | Detroit | Michigan | United States | 48236 |
| 251 | Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan | United States | 48054 |
| 252 | Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan | United States | 48503 |
| 253 | Genesee Hematology Oncology PC | Flint | Michigan | United States | 48503 |
| 254 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
| 255 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
| 256 | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
| 257 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
| 258 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
| 259 | Academic Hematology Oncology Specialists | Grosse Pointe Woods | Michigan | United States | 48236 |
| 260 | Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | United States | 48236 |
| 261 | Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods | Michigan | United States | 48236 |
| 262 | Allegiance Health | Jackson | Michigan | United States | 49201 |
| 263 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
| 264 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
| 265 | Ascension Borgess Cancer Center | Kalamazoo | Michigan | United States | 49009 |
| 266 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49048 |
| 267 | Sparrow Hospital | Lansing | Michigan | United States | 48912 |
| 268 | Hope Cancer Clinic | Livonia | Michigan | United States | 48154 |
| 269 | Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | United States | 48154 |
| 270 | Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan | United States | 48044 |
| 271 | Michigan Breast Specialists-Macomb Township | Macomb | Michigan | United States | 48044 |
| 272 | Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | United States | 48453 |
| 273 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
| 274 | Lakeland Hospital Niles | Niles | Michigan | United States | 49120 |
| 275 | Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | United States | 49444 |
| 276 | Henry Ford Medical Center-Columbus | Novi | Michigan | United States | 48377 |
| 277 | 21st Century Oncology-Pontiac | Pontiac | Michigan | United States | 48341 |
| 278 | Hope Cancer Center | Pontiac | Michigan | United States | 48341 |
| 279 | Newland Medical Associates-Pontiac | Pontiac | Michigan | United States | 48341 |
| 280 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
| 281 | Lake Huron Medical Center | Port Huron | Michigan | United States | 48060 |
| 282 | Spectrum Health Reed City Hospital | Reed City | Michigan | United States | 49677 |
| 283 | Great Lakes Cancer Management Specialists-Rochester Hills | Rochester Hills | Michigan | United States | 48309 |
| 284 | Ascension Saint Mary's Hospital | Saginaw | Michigan | United States | 48601 |
| 285 | Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | United States | 48604 |
| 286 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
| 287 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
| 288 | Henry Ford Macomb Health Center - Shelby Township | Shelby | Michigan | United States | 48315 |
| 289 | Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan | United States | 48312 |
| 290 | Ascension Saint Joseph Hospital | Tawas City | Michigan | United States | 48764 |
| 291 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
| 292 | Advanced Breast Care Center PLLC | Warren | Michigan | United States | 48088 |
| 293 | Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan | United States | 48093 |
| 294 | Macomb Hematology Oncology PC | Warren | Michigan | United States | 48093 |
| 295 | Michigan Breast Specialists-Warren | Warren | Michigan | United States | 48093 |
| 296 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
| 297 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
| 298 | Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | United States | 48661 |
| 299 | Metro Health Hospital | Wyoming | Michigan | United States | 49519 |
| 300 | Huron Gastroenterology PC | Ypsilanti | Michigan | United States | 48106 |
| 301 | Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | United States | 48197 |
| 302 | Riverwood Healthcare Center | Aitkin | Minnesota | United States | 56431 |
| 303 | Essentia Health - Baxter Clinic | Baxter | Minnesota | United States | 56425 |
| 304 | Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | United States | 56401 |
| 305 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
| 306 | Minnesota Oncology - Burnsville | Burnsville | Minnesota | United States | 55337 |
| 307 | Cambridge Medical Center | Cambridge | Minnesota | United States | 55008 |
| 308 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
| 309 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
| 310 | Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | United States | 56501 |
| 311 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
| 312 | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | United States | 55805 |
| 313 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
| 314 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
| 315 | Essentia Health - Ely Clinic | Ely | Minnesota | United States | 55731 |
| 316 | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | United States | 56537 |
| 317 | Essentia Health - Fosston | Fosston | Minnesota | United States | 56542 |
| 318 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
| 319 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
| 320 | Essentia Health - International Falls Clinic | International Falls | Minnesota | United States | 56649 |
| 321 | Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | United States | 55369 |
| 322 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
| 323 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
| 324 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
| 325 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
| 326 | Health Partners Inc | Minneapolis | Minnesota | United States | 55454 |
| 327 | Monticello Cancer Center | Monticello | Minnesota | United States | 55362 |
| 328 | Essentia Health - Moose Lake Clinic | Moose Lake | Minnesota | United States | 55767 |
| 329 | New Ulm Medical Center | New Ulm | Minnesota | United States | 56073 |
| 330 | Essentia Health - Park Rapids | Park Rapids | Minnesota | United States | 56470 |
| 331 | Fairview Northland Medical Center | Princeton | Minnesota | United States | 55371 |
| 332 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
| 333 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
| 334 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
| 335 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
| 336 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
| 337 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
| 338 | Saint Francis Regional Medical Center | Shakopee | Minnesota | United States | 55379 |
| 339 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
| 340 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
| 341 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
| 342 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
| 343 | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | United States | 55125 |
| 344 | Fairview Lakes Medical Center | Wyoming | Minnesota | United States | 55092 |
| 345 | University of Mississippi Medical Center | Jackson | Mississippi | United States | 39216 |
| 346 | Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | United States | 63011 |
| 347 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
| 348 | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | United States | 63628 |
| 349 | Cox Cancer Center Branson | Branson | Missouri | United States | 65616 |
| 350 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
| 351 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
| 352 | Parkland Health Center - Farmington | Farmington | Missouri | United States | 63640 |
| 353 | Centerpoint Medical Center LLC | Independence | Missouri | United States | 64057 |
| 354 | Capital Region Southwest Campus | Jefferson City | Missouri | United States | 65109 |
| 355 | Freeman Health System | Joplin | Missouri | United States | 64804 |
| 356 | Mercy Hospital Joplin | Joplin | Missouri | United States | 64804 |
| 357 | Saint Luke's Hospital of Kansas City | Kansas City | Missouri | United States | 64111 |
| 358 | Research Medical Center | Kansas City | Missouri | United States | 64132 |
| 359 | Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | United States | 64086 |
| 360 | Liberty Radiation Oncology Center | Liberty | Missouri | United States | 64068 |
| 361 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
| 362 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
| 363 | Heartland Regional Medical Center | Saint Joseph | Missouri | United States | 64506 |
| 364 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
| 365 | Barnes-Jewish Hospital | Saint Louis | Missouri | United States | 63110 |
| 366 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
| 367 | Mercy Hospital South | Saint Louis | Missouri | United States | 63128 |
| 368 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
| 369 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
| 370 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
| 371 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
| 372 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
| 373 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
| 374 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
| 375 | Mercy Hospital Washington | Washington | Missouri | United States | 63090 |
| 376 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
| 377 | Saint Vincent Healthcare | Billings | Montana | United States | 59101 |
| 378 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
| 379 | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | United States | 59701 |
| 380 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
| 381 | Saint Peter's Community Hospital | Helena | Montana | United States | 59601 |
| 382 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
| 383 | Saint Patrick Hospital - Community Hospital | Missoula | Montana | United States | 59802 |
| 384 | Community Medical Hospital | Missoula | Montana | United States | 59804 |
| 385 | Nebraska Medicine-Bellevue | Bellevue | Nebraska | United States | 68123 |
| 386 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
| 387 | Heartland Hematology and Oncology | Kearney | Nebraska | United States | 68845 |
| 388 | CHI Health Good Samaritan | Kearney | Nebraska | United States | 68847 |
| 389 | Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | United States | 68510 |
| 390 | Nebraska Medicine-Village Pointe | Omaha | Nebraska | United States | 68118 |
| 391 | Alegent Health Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
| 392 | Hematology and Oncology Consultants PC | Omaha | Nebraska | United States | 68122 |
| 393 | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
| 394 | Alegent Health Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
| 395 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131 |
| 396 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
| 397 | Midlands Community Hospital | Papillion | Nebraska | United States | 68046 |
| 398 | Carson Tahoe Regional Medical Center | Carson City | Nevada | United States | 89703 |
| 399 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
| 400 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
| 401 | Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson | Nevada | United States | 89052 |
| 402 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
| 403 | OptumCare Cancer Care at Seven Hills | Henderson | Nevada | United States | 89052 |
| 404 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
| 405 | GenesisCare USA - Henderson | Henderson | Nevada | United States | 89074 |
| 406 | Las Vegas Urology - Green Valley | Henderson | Nevada | United States | 89074 |
| 407 | Las Vegas Urology - Pebble | Henderson | Nevada | United States | 89074 |
| 408 | Urology Specialists of Nevada - Green Valley | Henderson | Nevada | United States | 89074 |
| 409 | Las Vegas Urology - Pecos | Las Vegas | Nevada | United States | 89074 |
| 410 | Desert West Surgery | Las Vegas | Nevada | United States | 89102 |
| 411 | OptumCare Cancer Care at Charleston | Las Vegas | Nevada | United States | 89102 |
| 412 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
| 413 | Hope Cancer Care of Nevada | Las Vegas | Nevada | United States | 89103 |
| 414 | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | United States | 89106 |
| 415 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
| 416 | Urology Specialists of Nevada - Central | Las Vegas | Nevada | United States | 89106 |
| 417 | GenesisCare USA - Las Vegas | Las Vegas | Nevada | United States | 89109 |
| 418 | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | United States | 89109 |
| 419 | Sunrise Hospital and Medical Center | Las Vegas | Nevada | United States | 89109 |
| 420 | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | United States | 89113 |
| 421 | Las Vegas Prostate Cancer Center | Las Vegas | Nevada | United States | 89113 |
| 422 | Las Vegas Urology - Sunset | Las Vegas | Nevada | United States | 89113 |
| 423 | Urology Specialists of Nevada - Southwest | Las Vegas | Nevada | United States | 89113 |
| 424 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
| 425 | Cancer Therapy and Integrative Medicine | Las Vegas | Nevada | United States | 89121 |
| 426 | Ann M Wierman MD LTD | Las Vegas | Nevada | United States | 89128 |
| 427 | Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 428 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 429 | GenesisCare USA - Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
| 430 | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 431 | Las Vegas Urology - Cathedral Rock | Las Vegas | Nevada | United States | 89128 |
| 432 | Las Vegas Urology - Smoke Ranch | Las Vegas | Nevada | United States | 89128 |
| 433 | OptumCare Cancer Care at MountainView | Las Vegas | Nevada | United States | 89128 |
| 434 | Urology Specialists of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 435 | Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | United States | 89135 |
| 436 | Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas | Nevada | United States | 89144 |
| 437 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
| 438 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
| 439 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
| 440 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
| 441 | GenesisCare USA - Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 442 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 443 | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | United States | 89149 |
| 444 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
| 445 | University Cancer Center | Las Vegas | Nevada | United States | 89169 |
| 446 | Hope Cancer Care of Nevada-Pahrump | Pahrump | Nevada | United States | 89048 |
| 447 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
| 448 | Saint Mary's Regional Medical Center | Reno | Nevada | United States | 89503 |
| 449 | Radiation Oncology Associates | Reno | Nevada | United States | 89509 |
| 450 | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | United States | 03756 |
| 451 | Memorial Sloan Kettering Basking Ridge | Basking Ridge | New Jersey | United States | 07920 |
| 452 | Hackensack University Medical Center | Hackensack | New Jersey | United States | 07601 |
| 453 | Overlook Hospital | Summit | New Jersey | United States | 07902 |
| 454 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87102 |
| 455 | Montefiore Medical Center-Einstein Campus | Bronx | New York | United States | 10461 |
| 456 | Montefiore Medical Center-Weiler Hospital | Bronx | New York | United States | 10461 |
| 457 | Montefiore Medical Center - Moses Campus | Bronx | New York | United States | 10467 |
| 458 | Memorial Sloan Kettering Commack | Commack | New York | United States | 11725 |
| 459 | Glens Falls Hospital | Glens Falls | New York | United States | 12801 |
| 460 | Memorial Sloan Kettering Westchester | Harrison | New York | United States | 10604 |
| 461 | Northwell Health/Center for Advanced Medicine | Lake Success | New York | United States | 11042 |
| 462 | North Shore University Hospital | Manhasset | New York | United States | 11030 |
| 463 | Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | United States | 10016 |
| 464 | Lenox Hill Hospital | New York | New York | United States | 10021 |
| 465 | Mount Sinai Hospital | New York | New York | United States | 10029 |
| 466 | NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | United States | 10032 |
| 467 | Memorial Sloan Kettering Cancer Center | New York | New York | United States | 10065 |
| 468 | NYP/Weill Cornell Medical Center | New York | New York | United States | 10065 |
| 469 | University of Rochester | Rochester | New York | United States | 14642 |
| 470 | AdventHealth Infusion Center Asheville | Asheville | North Carolina | United States | 28803 |
| 471 | UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | United States | 27599 |
| 472 | East Carolina University | Greenville | North Carolina | United States | 27834 |
| 473 | AdventHealth Hendersonville | Hendersonville | North Carolina | United States | 28792 |
| 474 | Wake Forest University Health Sciences | Winston-Salem | North Carolina | United States | 27157 |
| 475 | Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | United States | 58103 |
| 476 | Essentia Health - Jamestown Clinic | Jamestown | North Dakota | United States | 58401 |
| 477 | Indu and Raj Soin Medical Center | Beavercreek | Ohio | United States | 45431 |
| 478 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
| 479 | Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | United States | 45459 |
| 480 | Miami Valley Hospital South | Centerville | Ohio | United States | 45459 |
| 481 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
| 482 | Oncology Hematology Care Inc-Eden Park | Cincinnati | Ohio | United States | 45202 |
| 483 | Oncology Hematology Care Inc-Mercy West | Cincinnati | Ohio | United States | 45211 |
| 484 | University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | United States | 45219 |
| 485 | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | United States | 45220 |
| 486 | Oncology Hematology Care Inc-Anderson | Cincinnati | Ohio | United States | 45230 |
| 487 | Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | United States | 45236 |
| 488 | Bethesda North Hospital | Cincinnati | Ohio | United States | 45242 |
| 489 | Oncology Hematology Care Inc-Blue Ash | Cincinnati | Ohio | United States | 45242 |
| 490 | TriHealth Cancer Institute-Westside | Cincinnati | Ohio | United States | 45247 |
| 491 | TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | United States | 45255 |
| 492 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
| 493 | Mount Carmel East Hospital | Columbus | Ohio | United States | 43213 |
| 494 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
| 495 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
| 496 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
| 497 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
| 498 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
| 499 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
| 500 | Good Samaritan Hospital - Dayton | Dayton | Ohio | United States | 45406 |
| 501 | Miami Valley Hospital | Dayton | Ohio | United States | 45409 |
| 502 | Dayton Physician LLC-Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
| 503 | Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
| 504 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
| 505 | Delaware Radiation Oncology | Delaware | Ohio | United States | 43015 |
| 506 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
| 507 | Columbus Oncology and Hematology Associates | Dublin | Ohio | United States | 43016 |
| 508 | Oncology Hematology Care Inc-Healthplex | Fairfield | Ohio | United States | 45014 |
| 509 | Armes Family Cancer Center | Findlay | Ohio | United States | 45840 |
| 510 | Blanchard Valley Hospital | Findlay | Ohio | United States | 45840 |
| 511 | Orion Cancer Care | Findlay | Ohio | United States | 45840 |
| 512 | Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | United States | 45005-1066 |
| 513 | Dayton Physicians LLC-Atrium | Franklin | Ohio | United States | 45005 |
| 514 | Dayton Physicians LLC-Wayne | Greenville | Ohio | United States | 45331 |
| 515 | Wayne Hospital | Greenville | Ohio | United States | 45331 |
| 516 | Mount Carmel Grove City Hospital | Grove City | Ohio | United States | 43123 |
| 517 | Greater Dayton Cancer Center | Kettering | Ohio | United States | 45409 |
| 518 | First Dayton Cancer Care | Kettering | Ohio | United States | 45420 |
| 519 | Kettering Medical Center | Kettering | Ohio | United States | 45429 |
| 520 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
| 521 | Saint Rita's Medical Center | Lima | Ohio | United States | 45801 |
| 522 | OhioHealth Mansfield Hospital | Mansfield | Ohio | United States | 44903 |
| 523 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
| 524 | OhioHealth Marion General Hospital | Marion | Ohio | United States | 43302 |
| 525 | Dayton Physicians LLC-Signal Point | Middletown | Ohio | United States | 45042 |
| 526 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
| 527 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
| 528 | Newark Radiation Oncology | Newark | Ohio | United States | 43055 |
| 529 | Mercy Health Perrysburg Cancer Center | Perrysburg | Ohio | United States | 43551 |
| 530 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
| 531 | Dayton Physicians LLC-Wilson | Sidney | Ohio | United States | 45365 |
| 532 | Springfield Regional Cancer Center | Springfield | Ohio | United States | 45504 |
| 533 | Springfield Regional Medical Center | Springfield | Ohio | United States | 45505 |
| 534 | Saint Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
| 535 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
| 536 | Dayton Physicians LLC-Upper Valley | Troy | Ohio | United States | 45373 |
| 537 | Upper Valley Medical Center | Troy | Ohio | United States | 45373 |
| 538 | University of Cincinnati Cancer Center-West Chester | West Chester | Ohio | United States | 45069 |
| 539 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
| 540 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
| 541 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
| 542 | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | United States | 73120 |
| 543 | Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | United States | 74146 |
| 544 | Saint Alphonsus Medical Center-Baker City | Baker City | Oregon | United States | 97814 |
| 545 | Saint Charles Health System | Bend | Oregon | United States | 97701 |
| 546 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
| 547 | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | United States | 97015 |
| 548 | Bay Area Hospital | Coos Bay | Oregon | United States | 97420 |
| 549 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
| 550 | Saint Alphonsus Medical Center-Ontario | Ontario | Oregon | United States | 97914 |
| 551 | Providence Willamette Falls Medical Center | Oregon City | Oregon | United States | 97045 |
| 552 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
| 553 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
| 554 | Saint Charles Health System-Redmond | Redmond | Oregon | United States | 97756 |
| 555 | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | United States | 18103 |
| 556 | UPMC-Heritage Valley Health System Beaver | Beaver | Pennsylvania | United States | 15009 |
| 557 | Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | United States | 18017 |
| 558 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
| 559 | Pocono Medical Center | East Stroudsburg | Pennsylvania | United States | 18301 |
| 560 | UPMC Cancer Centers - Arnold Palmer Pavilion | Greensburg | Pennsylvania | United States | 15601 |
| 561 | Geisinger Medical Center-Cancer Center Hazleton | Hazleton | Pennsylvania | United States | 18201 |
| 562 | Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | United States | 18201 |
| 563 | Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | United States | 17033-0850 |
| 564 | UPMC-Johnstown/John P. Murtha Regional Cancer Center | Johnstown | Pennsylvania | United States | 15901 |
| 565 | Geisinger Medical Oncology-Lewisburg | Lewisburg | Pennsylvania | United States | 17837 |
| 566 | Lewistown Hospital | Lewistown | Pennsylvania | United States | 17044 |
| 567 | UPMC Cancer Center at UPMC McKeesport | McKeesport | Pennsylvania | United States | 15132 |
| 568 | UPMC-Coraopolis/Heritage Valley Radiation Oncology | Moon | Pennsylvania | United States | 15108 |
| 569 | UPMC-Magee Womens Hospital | Pittsburgh | Pennsylvania | United States | 15213 |
| 570 | UPMC-Presbyterian Hospital | Pittsburgh | Pennsylvania | United States | 15213 |
| 571 | UPMC-Saint Margaret | Pittsburgh | Pennsylvania | United States | 15215 |
| 572 | University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | United States | 15232 |
| 573 | UPMC-Shadyside Hospital | Pittsburgh | Pennsylvania | United States | 15232 |
| 574 | UPMC Jefferson Regional Radiation Oncology | Pittsburgh | Pennsylvania | United States | 15236 |
| 575 | UPMC-Passavant Hospital | Pittsburgh | Pennsylvania | United States | 15237 |
| 576 | UPMC-Saint Clair Hospital Cancer Center | Pittsburgh | Pennsylvania | United States | 15243 |
| 577 | Geisinger Cancer Services-Pottsville | Pottsville | Pennsylvania | United States | 17901 |
| 578 | Community Medical Center | Scranton | Pennsylvania | United States | 18510 |
| 579 | Geisinger Medical Oncology-Selinsgrove | Selinsgrove | Pennsylvania | United States | 17870 |
| 580 | UPMC Cancer Center at UPMC Northwest | Seneca | Pennsylvania | United States | 16346 |
| 581 | Geisinger Medical Group | State College | Pennsylvania | United States | 16801 |
| 582 | UPMC Uniontown Hospital Radiation Oncology | Uniontown | Pennsylvania | United States | 15401 |
| 583 | UPMC Washington Hospital Radiation Oncology | Washington | Pennsylvania | United States | 15301 |
| 584 | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
| 585 | Rhode Island Hospital | Providence | Rhode Island | United States | 02903 |
| 586 | Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | United States | 29316 |
| 587 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
| 588 | Prisma Health Cancer Institute - Easley | Easley | South Carolina | United States | 29640 |
| 589 | Gibbs Cancer Center-Gaffney | Gaffney | South Carolina | United States | 29341 |
| 590 | Greenville Health System Cancer Institute-Andrews | Greenville | South Carolina | United States | 29601 |
| 591 | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | United States | 29605 |
| 592 | Prisma Health Cancer Institute - Faris | Greenville | South Carolina | United States | 29605 |
| 593 | Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | United States | 29605 |
| 594 | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | United States | 29615 |
| 595 | Prisma Health Cancer Institute - Greer | Greer | South Carolina | United States | 29650 |
| 596 | Gibbs Cancer Center-Pelham | Greer | South Carolina | United States | 29651 |
| 597 | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | United States | 29672 |
| 598 | Spartanburg Medical Center | Spartanburg | South Carolina | United States | 29303 |
| 599 | MGC Hematology Oncology-Union | Union | South Carolina | United States | 29379 |
| 600 | Memorial Hospital | Chattanooga | Tennessee | United States | 37404 |
| 601 | Vanderbilt-Ingram Cancer Center Cool Springs | Franklin | Tennessee | United States | 37067 |
| 602 | Pulmonary Medicine Center of Chattanooga-Hixson | Hixson | Tennessee | United States | 37343 |
| 603 | Vanderbilt Breast Center at One Hundred Oaks | Nashville | Tennessee | United States | 37204 |
| 604 | Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | United States | 37232 |
| 605 | Memorial GYN Plus | Ooltewah | Tennessee | United States | 37363 |
| 606 | Dell Seton Medical Center at The University of Texas | Austin | Texas | United States | 78701 |
| 607 | Saint Joseph Regional Cancer Center | Bryan | Texas | United States | 77802 |
| 608 | Parkland Memorial Hospital | Dallas | Texas | United States | 75235 |
| 609 | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | United States | 75390 |
| 610 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
| 611 | Memorial Hermann Texas Medical Center | Houston | Texas | United States | 77030 |
| 612 | Memorial Hermann Northeast Hospital | Humble | Texas | United States | 77338 |
| 613 | Memorial Hermann The Woodlands Hospital | The Woodlands | Texas | United States | 77380 |
| 614 | Farmington Health Center | Farmington | Utah | United States | 84025 |
| 615 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
| 616 | South Jordan Health Center | South Jordan | Utah | United States | 84009 |
| 617 | Central Vermont Medical Center/National Life Cancer Treatment | Berlin | Vermont | United States | 05602 |
| 618 | University of Vermont Medical Center | Burlington | Vermont | United States | 05401 |
| 619 | University of Vermont and State Agricultural College | Burlington | Vermont | United States | 05405 |
| 620 | University of Virginia Cancer Center | Charlottesville | Virginia | United States | 22908 |
| 621 | Inova Schar Cancer Institute | Fairfax | Virginia | United States | 22031 |
| 622 | Inova Fairfax Hospital | Falls Church | Virginia | United States | 22042 |
| 623 | Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | United States | 98520 |
| 624 | Cancer Care Center at Island Hospital | Anacortes | Washington | United States | 98221 |
| 625 | Overlake Medical Center | Bellevue | Washington | United States | 98004 |
| 626 | PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | United States | 98225 |
| 627 | Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | United States | 98310 |
| 628 | Harrison Medical Center | Bremerton | Washington | United States | 98310 |
| 629 | Highline Medical Center-Main Campus | Burien | Washington | United States | 98166 |
| 630 | Providence Regional Cancer System-Centralia | Centralia | Washington | United States | 98531 |
| 631 | Swedish Cancer Institute-Edmonds | Edmonds | Washington | United States | 98026 |
| 632 | Saint Elizabeth Hospital | Enumclaw | Washington | United States | 98022 |
| 633 | Providence Regional Cancer Partnership | Everett | Washington | United States | 98201 |
| 634 | Saint Francis Hospital | Federal Way | Washington | United States | 98003 |
| 635 | Swedish Cancer Institute-Issaquah | Issaquah | Washington | United States | 98029 |
| 636 | Kadlec Clinic Hematology and Oncology | Kennewick | Washington | United States | 99336 |
| 637 | Providence Regional Cancer System-Lacey | Lacey | Washington | United States | 98503 |
| 638 | Saint Clare Hospital | Lakewood | Washington | United States | 98499 |
| 639 | PeaceHealth Saint John Medical Center | Longview | Washington | United States | 98632 |
| 640 | Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | United States | 98370 |
| 641 | Peninsula Cancer Center | Poulsbo | Washington | United States | 98370 |
| 642 | Valley Medical Center | Renton | Washington | United States | 98055 |
| 643 | Pacific Gynecology Specialists | Seattle | Washington | United States | 98104 |
| 644 | Swedish Medical Center-Ballard Campus | Seattle | Washington | United States | 98107 |
| 645 | Kaiser Permanente Washington | Seattle | Washington | United States | 98112 |
| 646 | Swedish Medical Center-First Hill | Seattle | Washington | United States | 98122-4307 |
| 647 | Swedish Medical Center-Cherry Hill | Seattle | Washington | United States | 98122-5711 |
| 648 | PeaceHealth United General Medical Center | Sedro-Woolley | Washington | United States | 98284 |
| 649 | Olympic Medical Cancer Care Center | Sequim | Washington | United States | 98384 |
| 650 | Providence Regional Cancer System-Shelton | Shelton | Washington | United States | 98584 |
| 651 | MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley | Washington | United States | 99216 |
| 652 | MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane | Washington | United States | 99204 |
| 653 | MultiCare Deaconess Cancer and Blood Specialty Center - North | Spokane | Washington | United States | 99218 |
| 654 | Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington | United States | 98405 |
| 655 | Northwest Medical Specialties PLLC | Tacoma | Washington | United States | 98405 |
| 656 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
| 657 | Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | United States | 99362 |
| 658 | North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | United States | 98902 |
| 659 | Providence Regional Cancer System-Yelm | Yelm | Washington | United States | 98597 |
| 660 | United Hospital Center | Bridgeport | West Virginia | United States | 26330 |
| 661 | WVUH-Berkely Medical Center | Martinsburg | West Virginia | United States | 25401 |
| 662 | West Virginia University Healthcare | Morgantown | West Virginia | United States | 26506 |
| 663 | Camden Clark Medical Center | Parkersburg | West Virginia | United States | 26101 |
| 664 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
| 665 | Northwest Wisconsin Cancer Center | Ashland | Wisconsin | United States | 54806 |
| 666 | Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | United States | 53105 |
| 667 | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | United States | 54729 |
| 668 | Aurora Saint Luke's South Shore | Cudahy | Wisconsin | United States | 53110 |
| 669 | Marshfield Clinic Cancer Center at Sacred Heart | Eau Claire | Wisconsin | United States | 54701 |
| 670 | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
| 671 | Aurora Health Center-Fond du Lac | Fond Du Lac | Wisconsin | United States | 54937 |
| 672 | Aurora Health Care Germantown Health Center | Germantown | Wisconsin | United States | 53022 |
| 673 | Aurora Cancer Care-Grafton | Grafton | Wisconsin | United States | 53024 |
| 674 | Aurora BayCare Medical Center | Green Bay | Wisconsin | United States | 54311 |
| 675 | Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | United States | 53142 |
| 676 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
| 677 | University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | United States | 53792 |
| 678 | Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | United States | 54143 |
| 679 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
| 680 | Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | United States | 53209 |
| 681 | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
| 682 | Medical College of Wisconsin | Milwaukee | Wisconsin | United States | 53226 |
| 683 | Aurora Sinai Medical Center | Milwaukee | Wisconsin | United States | 53233 |
| 684 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
| 685 | ProHealth D N Greenwald Center | Mukwonago | Wisconsin | United States | 53149 |
| 686 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
| 687 | ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | United States | 53066 |
| 688 | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | United States | 54904 |
| 689 | Aurora Cancer Care-Racine | Racine | Wisconsin | United States | 53406 |
| 690 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
| 691 | Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | United States | 53081 |
| 692 | Ascension Saint Michael's Hospital | Stevens Point | Wisconsin | United States | 54481 |
| 693 | Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | United States | 54482 |
| 694 | Aurora Medical Center in Summit | Summit | Wisconsin | United States | 53066 |
| 695 | Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | United States | 54241 |
| 696 | Aurora Cancer Care-Waukesha | Waukesha | Wisconsin | United States | 53188 |
| 697 | ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | United States | 53188 |
| 698 | UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | United States | 53188 |
| 699 | Marshfield Clinic-Wausau Center | Wausau | Wisconsin | United States | 54401 |
| 700 | Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | United States | 53226 |
| 701 | Aurora West Allis Medical Center | West Allis | Wisconsin | United States | 53227 |
| 702 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
| 703 | Big Horn Basin Cancer Center | Cody | Wyoming | United States | 82414 |
| 704 | Billings Clinic-Cody | Cody | Wyoming | United States | 82414 |
| 705 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
Sponsors and Collaborators
- Alliance for Clinical Trials in Oncology
- National Cancer Institute (NCI)
- GlaxoSmithKline
- Genentech, Inc.
- Brain Science Foundation
Investigators
- Study Chair: Priscilla Brastianos, MD, Massachusetts General Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- A071401
- NCI-2015-00546