Acute Effects of HIIT and SSMIT on Intraocular Pressure Among Sedentary Individuals

• Sponsor: University of Malaya (Other)
• Overall Status: Completed
• CT.gov ID: NCT04133857
• Collaborator: (none)
• Enrollment: 40
• Location: 1
• Arms: 2
• Actual Duration (Months): 1.9
• Patients Per Site Per Month: 21

Study Details

Study Description

Brief Summary

Purpose to study the acute effects of both forms of aerobic exercise (HIIT and SSMIT) on intraocular pressure among healthy sedentary individuals

Condition or Disease	Intervention/Treatment	Phase
Intraocular Pressure	Other: aerobic exercise	N/A

Detailed Description

40 participants were recruited and divided into 2 groups. Each group performed 2 exercise protocols with a 4 day washout period between them.

The intraocular pressure was measured before the exercise and after the exercise in 5 minute periods up until 30 minutes post exercise.

The intraocular pressure was measured using a handheld rebound tonometer.

Study Design

• Study Type: Interventional
• Actual Enrollment: 40 participants
• Allocation: Randomized
• Intervention Model: Crossover Assignment
• Masking: Triple (Participant, Investigator, Outcomes Assessor)
• Primary Purpose: Treatment
• Official Title: Acute Effects of High Intensity Interval Training (HIIT) and Steady State Moderate Intensity Training (SSMIT) on Intraocular Pressure Among Sedentary Individuals
• Actual Study Start Date: Jan 1, 2018
• Actual Primary Completion Date: Jan 31, 2018
• Actual Study Completion Date: Feb 28, 2018

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Group A undergo HIIT first then SSMIT protocol	Other: aerobic exercise; aerobic exercise HIIT : High intensity interval training SSMIT : Steady state moderate intensity training
Active Comparator: Group B undergo SSMIT first then HIIT protocol	Other: aerobic exercise; aerobic exercise HIIT : High intensity interval training SSMIT : Steady state moderate intensity training

Outcome Measures

Primary Outcome Measures

1. Changes in intraocular pressure [30 minutes]

   changes in intraocular pressure before and after exervcise

Secondary Outcome Measures

1. compare which form of exercise (HIIT & SSMIT) is superior in reducing intraocular pressure [30 days]

   difference in intraocular pressure reduction observed between each exercise protocol

Eligibility Criteria

Criteria

• Ages Eligible for Study: 21 Years to 60 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• all University hospital staff

Exclusion Criteria:

• previous ocular trauma

• surgery in the eligible eye

• known case of glaucoma or glaucoma suspect (IOP > 21mmHg)

• history of glaucoma laser procedure/surgery within 6 months in eligible eye

• unable to undergo IOP measurements

• undiagnosed visual condition

• any uncontrolled medical condition such as end stage renal failure, uncontrolled diabetes and uncontrolled hypertension

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University Malaya	Kuala Lumpur	Wilayah Perseketuan	Malaysia	59100

Sponsors and Collaborators

• University of Malaya

Investigators

None specified.

Study Documents (Full-Text)

• Study Protocol and Statistical Analysis Plan - Oct 15, 2019

More Information

Publications

None provided.

• Responsible Party: Prof Mohd Nahar Azmi Mohamed, associate professor, University of Malaya
• ClinicalTrials.gov Identifier: NCT04133857
• Other Study ID Numbers: 20171031-5738
• First Posted: Oct 21, 2019
• Last Update Posted: Oct 21, 2019
• Last Verified: Oct 1, 2019

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of Oct 21, 2019