Clincosm LogoSign in Get a demo

Investigation of Genetic Risk of Atrial Fibrillation

Sponsor
Nagoya University (Other)
Overall Status
Unknown status
CT.gov ID
NCT00412438
Collaborator
(none)
1,000
Enrollment
1
Location

Study Details

Study Description

Brief Summary

The atrial fibrillation (AF) is the most common cardiac rhythm disturbance that is responsible for substantial morbidity and mortality independent of associated heart disease or other risk factors. Even in the absence of preexisting cardiovascular disease, AF remains significantly associated with excess mortality rates. The current unsatisfactory treatment for AF comes from lack of understanding of the pathophysiology of AF. The purpose of this study is to identify gene polymorphisms that confer susceptibility to atrial fibrillation. Patients with AF（N=500） and healthy volunteer（N=1000） without AF are enrolled in this study. Patients with coronary artery disease, severe valvular heart disease, cardiomyopathy or heart failure were excluded from the study.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Observational Model:
    Case-Control
    Time Perspective:
    Other
    Official Title:
    Investigation of Genetic Risk of Atrial Fibrillation
    Study Start Date :
    Oct 1, 2006

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      Yes
      Inclusion Criteria:
      • Clinical diagnosis of atrial fibirillation
      Exclusion Criteria:

      • coronary artery disease

      • severe valvular heart disease

      • cardiomyopathy

      • heart failure

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University Nagoya Aichi Japan

      Sponsors and Collaborators

      • Nagoya University

      Investigators

      • Study Chair: Kenji Yasui, MD, Phd, Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00412438
      Other Study ID Numbers:
      • RIEM-G-1
      First Posted:
      Dec 18, 2006
      Last Update Posted:
      Dec 18, 2006
      Last Verified:
      Dec 1, 2006
      Keywords provided by , ,
      Atrial Fibrillation
      Additional relevant MeSH terms:
      Atrial Fibrillation

      Study Results

      No Results Posted as of Dec 18, 2006