Clincosm LogoSign in Get a demo

Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis

Sponsor
Zunyi Medical College (Other)
Overall Status
Completed
CT.gov ID
NCT05915637
Collaborator
(none)
336
Enrollment
1
Location
14
Actual Duration (Months)
24
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

To investigate and analyze the status of preoperative frailty and its influencing factors in elderly patients with colorectal cancer using FRALL scale and other related scales, and to explore the correlation between preoperative frailty and early prognosis in elderly patients with colorectal cancer, so as to attract the attention of medical staff to preoperative frailty in this population and provide a preliminary research basis for the study of frailty intervention in these patients.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    336 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis
    Actual Study Start Date :
    Sep 1, 2021
    Actual Primary Completion Date :
    Nov 1, 2022
    Actual Study Completion Date :
    Nov 1, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Fatigue Assessment [7 days]

      Status of frailty will be assessed by FRALL Scale

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    60 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    1. age ≥60 years old;

    2. Colorectal cancer was diagnosed according to the Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer (2020 edition) and planned to undergo elective laparoscopic radical resection of colorectal cancer;

    3. able to complete physical assessment without communication barriers;

    4. voluntarily participated in this study after informed consent.

    Exclusion Criteria:

    1. taking antidepressants, levodopa, donepezil hydrochloride and other drugs;

    2. patients with preoperative colorectal cancer surgery or neoadjuvant therapy;

    3. patients with TNM stage Ⅳ;

    4. complicated with other malignant tumors except primary skin cancer or melanoma.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Yongmei Zhang Zunyi Guizhou China 563000

    Sponsors and Collaborators

    • Zunyi Medical College

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Yongmei Zhang, Study Director, Zunyi Medical College
    ClinicalTrials.gov Identifier:
    NCT05915637
    Other Study ID Numbers:
    • KLLY-2021-025
    First Posted:
    Jun 23, 2023
    Last Update Posted:
    Jun 23, 2023
    Last Verified:
    Jun 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Colorectal Neoplasms
    Frailty

    Study Results

    No Results Posted as of Jun 23, 2023