CeKATU: Investigation of the Transfusion Practices in Surgical Patients in Turkey
Study Details
Study Description
Brief Summary
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors and transfusion related patient outcomes are investigated.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Patient Blood Management (PBM) is an evidence based multidisciplinary approach for the care of patients who may need blood transfusion. The aim of PBM is achieving better patient outcomes by focusing on the patients' own blood as a source.
To date PBM is considered "good transfusion practice" and is being implemented in a growing number of countries. The Turkish Society of Anesthesiologists PBM Task Force is working on this subject since 4 years and decided to conduct a study. Before starting a PBM program, the transfusion practices of clinicians working at diverse surgical fields; differences between current transfusion practices and PBM strategies; the areas for improvement and the obstacles that could prevent change could be identified with this study. Data collection will also serve to identify the current situation as a reference and to control the achievement of the PBM's aim: improving clinical outcomes. These data will be refered as The Turkish National Perioperative Transfusion Study (TULIP TS) data.
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey.
The study evaluates i. The perioperative transfusion rates of RBCs, FFP and platelets. ii. With which reasons the anesthesiologists decide to transfuse a patient (co morbidities of the patients, physiologic transfusion triggers, hemoglobin trigger, uncontrolled bleeding, on request from surgeon etc.).
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The relation of transfusion and the patients co-morbidity index, the P POSSUM score and SORT score; anesthesia methods; monitorisation methods (hemodynamic, coagulation); amount of bleeding; type of surgery; type of hospital.
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The relation of transfusion and patient outcomes (unanticipated ICU admission, prolonged ICU stay, acute renal failure, thromboembolic events, ischemic events, pulmonary complications, cardiac advers events, infections, acute respiratory distress, infection, all-cause mortality).
Study Design
Outcome Measures
Primary Outcome Measures
- Preoperative amount of blood products transfused [Before surgery at day 0]
Preoperative amount of blood products: RBCs,FFP and platelets transfused
- Intraoperative amount of blood products transfused [During surgery at day 0]
Intraoperative amount of blood products: RBC's,FFP and platelets transfused
- Postoperative amount of blood products transfused [24 hours after surgery]
Postoperative amount of blood products: RBCs,FFP and platelets transfused
Secondary Outcome Measures
- Preoperative transfusion indications [Before surgery at day 0]
The reasons to decide to transfuse (factors determining transfusion) blood products
- Intraoperative transfusion indications [During surgery at day 1]
The reasons to decide to transfuse (factors determining transfusion) blood products
- Postoperative transfusion indications [24 hours after surgery]
The reasons to decide to transfuse (factors determining transfusion) blood products
- Unanticipated ICU admission [After surgery at day 1]
Whether the patient had an unanticipated ICU admission
- Prolonged length of stay in ICU [After surgery at day 2]
Whether the patient had a prolonged length of stay in ICU
- Acute renal failure [After surgery at day 2]
Whether the patient had acute renal failure
- Thromboembolic event [After surgery at day 2]
Whether the patient had a thromboembolic event concerning lungs (pulmonary embolism), brain (stroke), gastrointestinal tract, kidneys, or extremities etc.
- Ischemic event [After surgery at day 2]
Whether the patient had an ischemic event concerning heart, nervous system,limb, gastrointestinal tract etc.
- Infection [After surgery at day 2]
Whether the patient had infection: wound, pneumonia, urinary, sepsis etc.
- Acute respiratory distress [After surgery at day 2]
Whether the patient had acute respiratory distress
- Mortality [after surgery at day 30]
Whether the patient died: all cause mortality
- Preoperative anemia [Before surgery at day 0]
Whether the patient had anemia (Hemoglobin male < 13 female < 12 g/dL)
- Preoperative coagulopathy [Before surgery at day 0]
Whether the patient had coagulopathy due to disease or drugs
- Pretransfusion hemoglobin values [Before surgery at day 0]
The hemoglobin concentration before transfusion
- Pretransfusion hemoglobin values [During surgery at day 1]
The hemoglobin concentration before transfusion
- Pretransfusion hemoglobin values [After surgery at day 2]
The hemoglobin concentration before transfusion
- Advers cardiac events [After surgery at day 30]
Whether the patient had an advers cardiac event: myocardial infaction; non fatal cardiac arest; arrhytmia; cardiogenic pulmonary edema etc
Eligibility Criteria
Criteria
Inclusion Criteria:
Patients undergoing major elective surgery
Exclusion Criteria:
Trauma patients, emergency surgery
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Acibadem University Mehmet Ali Aydinlar Atakent Hospital | Ankara | Turkey | ||
| 2 | Ankara University Cebeci Medical Center | Ankara | Turkey | ||
| 3 | Ankara University Ibni Sina Hospital | Ankara | Turkey | ||
| 4 | Başkent University Ankara Hospital | Ankara | Turkey | ||
| 5 | Gazi University Medical Faculty | Ankara | Turkey | ||
| 6 | Hacettepe University Medical Faculty | Ankara | Turkey | ||
| 7 | Private Cankaya Hospital | Ankara | Turkey | ||
| 8 | Ufuk University Medical Faculty Dr. Ridvan Ege Training and Research Hospital | Ankara | Turkey | ||
| 9 | University of Health sciences Ankara Child Health and Diseases Hematology Oncology Training and research Hospital | Ankara | Turkey | ||
| 10 | University of Health Sciences Ankara Numune Training and Research Hospital | Ankara | Turkey | ||
| 11 | University of Health Sciences Ankara Training and Research Hospital | Ankara | Turkey | ||
| 12 | University of Health Sciences Diskapi Yildirim Beyazit Trainig Research Hospital | Ankara | Turkey | ||
| 13 | University of Health Sciences Dr Abdurrahman Yurtaslanı Ankara Oncology Training and Research Hospital | Ankara | Turkey | ||
| 14 | University of Health Sciences Kecioren Training and Research Hospital | Ankara | Turkey | ||
| 15 | University of Health Sciences Turkiye Yuksek Ihtisas Training and Research Hospital | Ankara | Turkey | ||
| 16 | University of Health Sciences Yenimahalle Training and Research Hospital | Ankara | Turkey | ||
| 17 | University of Health Sciences Zubeyde Hanim Gynecology and Maternity Training and Research Hospital | Ankara | Turkey | ||
| 18 | University of Technology and Economics Medical Faculty | Ankara | Turkey | ||
| 19 | Akdeniz University Medical Faculty | Antalya | Turkey | ||
| 20 | University of Health Sciences Antalya Training and Research Hospital | Antalya | Turkey | ||
| 21 | Balikesir University Training and Research Hospital | Balıkesir | Turkey | ||
| 22 | Uludağ University Medical Faculty | Bursa | Turkey | ||
| 23 | University of Health Sciences Bursa Yuksek Ihtisas Training and Research Hospital | Bursa | Turkey | ||
| 24 | Trakya University Medical Faculty | Edirne | Turkey | ||
| 25 | Fırat University Medical Faculty | Elazığ | Turkey | ||
| 26 | Erzincan University Mengucek Gazi Training and Research Hospital | Erzincan | Turkey | ||
| 27 | Eskisehir Osmangazi University Medical Faculty | Eskişehir | Turkey | ||
| 28 | Suleyman Demirel University Medical Faculty | Isparta | Turkey | ||
| 29 | Acibadem University Altunizade Hospital | Istanbul | Turkey | ||
| 30 | Istanbul Medeniyet University Goztepe Training and Research Hospital | İstanbul | Turkey | ||
| 31 | Istanbul University Medical Faculty | Istanbul | Turkey | ||
| 32 | Marmara University Pendik Training and Research Hospital | Istanbul | Turkey | ||
| 33 | University of Health Sciences Fatih Sultan Mehmet Training and Research Hospital | Istanbul | Turkey | ||
| 34 | University of Health Sciences Haydarpasa Numne Training and Research Hospital | Istanbul | Turkey | ||
| 35 | University of Health Sciences Istanbul Training and Research Hospital | Istanbul | Turkey | ||
| 36 | University of Health Sciences Kanuni Sultan Suleyman Training and Research Hospital | Istanbul | Turkey | ||
| 37 | University of Health Sciences Okmeydanı Training and Research Hospital | Istanbul | Turkey | ||
| 38 | University of Health Sciences Umraniye Training and Research Hospital | Istanbul | Turkey | ||
| 39 | Dokuz Eylul University Medical Faculty | İzmir | Turkey | ||
| 40 | University of Health Sciences Bozyaka Training Research Hospital | İzmir | Turkey | ||
| 41 | University of Health Sciences İzmir Tepecik Training and Research Hospital | İzmir | Turkey | ||
| 42 | Sutcu Imam University Medical Faculty | Kahramanmaraş | Turkey | ||
| 43 | Erciyes University Medical Faculty | Kayseri | Turkey | ||
| 44 | University of Health Sciences Kayseri Training and Research Hospital | Kayseri | Turkey | ||
| 45 | Anadolu Health Center Hospital | Kocaeli | Turkey | ||
| 46 | University of Health Sciences Derince Training and Research Hospital | Kocaeli | Turkey | ||
| 47 | Necmettin Erbakan University Meram Medical Faculty Center for Health and Research | Konya | Turkey | ||
| 48 | Selcuk University Medical Faculty | Konya | Turkey | ||
| 49 | University of Health Sciences Konya Training and Research Hospital | Konya | Turkey | ||
| 50 | Inonu University Liver Transplantation Institute | Malatya | Turkey | ||
| 51 | Manisa Celal Bayar University Medical Faculty Hafsa Sultan Hospital | Manisa | Turkey | ||
| 52 | Mersin University Medical Faculty | Mersin | Turkey | ||
| 53 | Ordu University Medical Faculty | Ordu | Turkey | ||
| 54 | Osmaniye State Hospital | Osmaniye | Turkey | ||
| 55 | Ondokuz Mayıs University Medical Faculty | Samsun | Turkey | ||
| 56 | Namık Kemal University Medical Faculty | Tekirdağ | Turkey | ||
| 57 | Karadeniz Technical University Medical Faculty Farabi Hospital | Trabzon | Turkey | ||
| 58 | Tunceli State Hospital | Tunceli | Turkey | ||
| 59 | Van Yuzuncuyıl University Medical Faculty Dursun Odabası Center | Van | Turkey | ||
| 60 | Bulent Ecevit University Medical Faculty Center for Health and Research | Zonguldak | Turkey | ||
| 61 | Hitit University Corum Erol Olcok Training and Research Hospital | Çorum | Turkey |
Sponsors and Collaborators
- Diskapi Teaching and Research Hospital
- Turkish Society of Anesthesiology and Reanimation
Investigators
- Principal Investigator: Dilek Unal, Assoc Prof, Netherlands: Ministry of Health, Welfare and Sports
Study Documents (Full-Text)
None provided.More Information
Publications
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- Dilek Yazıcıoglu Unal