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FER-IRM: Study of Iron Accumulation Measured in MRI in Non-pathological Aging

Sponsor
University Hospital, Lille (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04659824
Collaborator
(none)
190
Enrollment
36
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    190 participants
    Observational Model:
    Cohort
    Time Perspective:
    Cross-Sectional
    Official Title:
    Study of Iron Accumulation Measured in MRI in Non-pathological Aging
    Anticipated Study Start Date :
    Feb 1, 2021
    Anticipated Primary Completion Date :
    Feb 1, 2024
    Anticipated Study Completion Date :
    Feb 1, 2024

    Arms and Interventions

    Arm Intervention/Treatment
    Healthy

    Outcome Measures

    Primary Outcome Measures

    1. Correlation coefficient between iron load in MRI and age [baseline]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 95 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Men or women between 18 and 95 years old

    • French speaker with capability to understand the instructions

    • Health insurance

    Exclusion Criteria:

    • Pregnancy

    • minor subject

    • no informed consent agreement

    • subject enrolled in pharmaceutic study or exclusion period

    • MRI contra-indications

    • Neurological or psychiatric disorders

    • MOCA < 26

    • Psychotropic drugs

    • More than 3 MRI exams

    • More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months

    • Unable to follow the entire protocol according to the investigator

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • University Hospital, Lille

    Investigators

    • Principal Investigator: GrĂ©gory KUCHCINSKI, MD, University Hospital, Lille

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Lille
    ClinicalTrials.gov Identifier:
    NCT04659824
    Other Study ID Numbers:
    • 2019_24
    • 2020-A00491-38
    First Posted:
    Dec 9, 2020
    Last Update Posted:
    Dec 9, 2020
    Last Verified:
    Nov 1, 2020
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No

    Study Results

    No Results Posted as of Dec 9, 2020