IRONWOMEN: Iron Deficiency Anemia Among Chinese Pregnant Women: a Multi-center Prospective Cohort Study
Study Details
Study Description
Brief Summary
Iron deficiency anemia during pregnancy, which may lead to adverse pregnancy outcomes, was a serious health problem in China. Various iron supplements used in different regions of China, however, the effects have not been well investigated. The objective of this study is to investigate the diagnosis, treatment and prognosis of iron deficiency and iron deficiency anemia in Chinese pregnant women.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
This is a nationwide multicenter prospective cohort study conducted in seven hospitals in China to investigate the diagnosis, treatment and prognosis of iron deficiency and iron deficiency anemia in Chinese pregnant women. This study will enroll about 6000-7000 pregnant women, who established a health record in the seven hospitals. Demographic characteristics, laboratory tests, behavior habits during pregnancy, mental status, and pregnancy outcomes will been collected. All information will collect by a pregnant women self-reported questionnaire and the electronic medical record system in hospitals at three timing points: 6-15 gestational weeks, 30-34 gestational weeks and one week after delivery.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Exposure group Chinese women with iron deficiency anemia (IDA) during pregnancy. |
Other: Iron deficiency anemia in Chinese pregnant women
Iron deficiency anemia exists in Chinese pregnant women during pregnancy
|
| Control group Chinese women without iron deficiency anemia (IDA) during pregnancy. |
Outcome Measures
Primary Outcome Measures
- adverse maternal outcomes [40 weeks]
Including iron deficiency anemia rate, pregnancy hypertension syndrome rate, gestational diabetes mellitus rate, cesarean section rate, and other adverse maternal outcomes rate. The definition of adverse maternal outcome was according to International Glossary on Infertility and Fertility Care (2017), and the rate of adverse maternal outcome was calculated by the number of adverse maternal outcome divided by the total number of pregnant women.
- adverse neonatal outcomes [40 weeks]
Including miscarriage rate, premature birth rate, birth defect rate, low birth weight rate, and other adverse neonatal outcomes. The definitions of adverse neonatal outcomes were according to International Glossary on Infertility and Fertility Care (2017), and the rate of adverse neonatal outcomes were calculated by the number of advers neonatal outcomes divided by the total number of pregnancy or birth.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Pregnant women who registered an antenatal care file at the survey hospital ;
-
Signed informed consent.
Exclusion Criteria:
- Participated in any drug or nutritional clinical trial from 3 months before pregnancy to recruitment.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Peking University People's Hospital | Beijing | Beijing | China | |
| 2 | Chongqing Health center for women and Children | Chongqing | Chongqing | China | |
| 3 | Xiamen Maternal and Child Care Hospital | Xiamen | Fujian | China | |
| 4 | Hubei Maternal and Child Care Hospital | Wuhan | Hubei | China | |
| 5 | Yanan University Affiliated Hospital | Yanan | Shanxi | China | |
| 6 | The West China Second University Hospital | Chengdu | Sichuan | China | 610041 |
| 7 | Women'S Hospital School of Medicine Zhejiang University | Hangzhou | Zhejiang | China |
Sponsors and Collaborators
- West China Hospital
- West China Second University Hospital
Investigators
- Study Chair: Xin Sun, Doctor, West China Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
- IDA_2019