Is it Possible to Treat Cyanide Poisoning With HBO?

Sponsor
Rigshospitalet, Denmark (Other)
Overall Status
Completed
CT.gov ID
NCT00399100
Collaborator
(none)
20
1

Study Details

Study Description

Brief Summary

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.

Condition or Disease Intervention/Treatment Phase
  • Procedure: HBO - hyperbaric oxygen treatment

Study Design

Study Type:
Observational
Observational Model:
Case-Control
Time Perspective:
Prospective
Actual Study Start Date :
Nov 1, 2006
Actual Primary Completion Date :
Nov 1, 2006
Actual Study Completion Date :
Nov 1, 2006

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Inclusion Criteria:
    • Going to receive HBO treatment for carbon monoxide poisoning from fire accidents
    Exclusion Criteria:
    • Under 18 years

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet København Ø Denmark 2100

    Sponsors and Collaborators

    • Rigshospitalet, Denmark

    Investigators

    • Principal Investigator: Pia Lawson-Smith, Doctor, Rigshospitalet HOC, Trykkammeret

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00399100
    Other Study ID Numbers:
    • 01-277/99
    First Posted:
    Nov 14, 2006
    Last Update Posted:
    Mar 21, 2018
    Last Verified:
    Nov 1, 2006
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Mar 21, 2018