Is it Possible to Treat Cyanide Poisoning With HBO?
Sponsor
Rigshospitalet, Denmark (Other)
Overall Status
Completed
CT.gov ID
NCT00399100
Collaborator
(none)
20
1
Study Details
Study Description
Brief Summary
People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.
The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Study Design
Study Type:
Observational
Observational Model:
Case-Control
Time Perspective:
Prospective
Actual Study Start Date
:
Nov 1, 2006
Actual Primary Completion Date
:
Nov 1, 2006
Actual Study Completion Date
:
Nov 1, 2006
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Inclusion Criteria:
- Going to receive HBO treatment for carbon monoxide poisoning from fire accidents
Exclusion Criteria:
- Under 18 years
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet | København Ø | Denmark | 2100 |
Sponsors and Collaborators
- Rigshospitalet, Denmark
Investigators
- Principal Investigator: Pia Lawson-Smith, Doctor, Rigshospitalet HOC, Trykkammeret
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00399100
Other Study ID Numbers:
- 01-277/99
First Posted:
Nov 14, 2006
Last Update Posted:
Mar 21, 2018
Last Verified:
Nov 1, 2006