Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

• Sponsor: University Hospital, Ghent (Other)
• Overall Status: Suspended
• CT.gov ID: NCT00117416
• Collaborator: (none)
• Enrollment: 60
• Location: 1

Study Details

Study Description

Brief Summary

The purpose of this study is to evaluate the renal perfusion depending on the MAP.

Condition or Disease	Intervention/Treatment	Phase
Kidney Failure, Acute	Procedure: controlling the MAP	N/A

Study Design

• Study Type: Interventional
• Allocation: Randomized
• Intervention Model: Crossover Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: MAP and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function
• Study Start Date: Feb 1, 2003

Outcome Measures

Primary Outcome Measures

1. creatinine clearance after 4 hours []

Secondary Outcome Measures

1. resistance index []

2. diuresis []

3. urinary indices of renal function []

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Over 18 years old

• Intensive care patient

• Treated with vasopressor

• Given informed consent

• Arterial infusion

• A bladder catheter

Exclusion Criteria:

• Anamneses of hypertension

• Neurological trauma

• Acute renal insufficiency other than prerenal or acute tubular necrosis etiology

• Hepatorenal syndrome

• Treated with diuretics

• Mechanical ventilation and unstable

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University Hospital Ghent	Ghent		Belgium	9000

Sponsors and Collaborators

• University Hospital, Ghent

Investigators

• Principal Investigator: Eric Hoste, MD, PhD, University Hospital, Ghent

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

• Website of the University Hospital Ghent

Publications

None provided.

• Responsible Party: University Hospital, Ghent
• ClinicalTrials.gov Identifier: NCT00117416
• Other Study ID Numbers: 2002/382
• First Posted: Jul 6, 2005
• Last Update Posted: Jul 7, 2021
• Last Verified: Jul 1, 2021

• Additional relevant MeSH terms: Renal Insufficiency; Acute Kidney Injury

Study Results

No Results Posted as of Jul 7, 2021