Effect of Hip Abductors Versus Knee Extensor Strengthening in Knee Osteoarthritis

Sponsor

Cairo University (Other)

Overall Status

Completed

CT.gov ID

NCT04503304

Collaborator

(none)

Enrollment

Location

Arms

Actual Duration (Months)

17.3

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This study will try to answer the following question:

Would strengthening of hip abductors be equal to, or more effective than, knee extensors strengthening in improving pain, function and knee extensors isometric strength in patients with knee Osteoarthritis

Condition or Disease	Intervention/Treatment	Phase
Knee Osteoarthritis	Other: Exercises	N/A

Detailed Description

A total of 70 patients with knee Osteoarthritis will be recruited All patients who will participate in the study will be referred by orthopedists. Patients with knee osteoarthritis will be included with age ranges from 50-70. They will be randomized into 2 groups; hip abductors strengthening (HAS) group a will receive hip abductors strengthening exercises, and knee extensors strengthening (KES) group will receive quadriceps strengthening exercise.

All patients who will meet the study criteria will get a complete knowledge of the objectives and procedures of the study.

Inclusion criteria:

Patients with knee Osteoarthritis grade II- III Kellgren- Lawrence scores
Their age is 50-70[Wang et al.,2019].
Body mass index (BMI) 25-30.

Exclusion criteria:

Patients who had surgical intervention in the knee and/or hip.
Fracture in the lower limbs.
Malignancy
Any associated ligamentous injuries in knee or ankle.
Spinal Cord Injury.
Hormonal imbalance or on hormonal therapy
Knee injection within the last 6 months prior to the study. Outcome parameters including Quadriceps Muscle Strength, the arabic version of Western Ontario and McMaster Universities Arthritis Index questionnaire total score and 3 subscales and Timed Up and Go test score

Study Design

Study Type:

Interventional

Actual Enrollment :

70 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Intervention Model Description:

2 groups; hip abductors strengthening (HAS) group a will receive hip abductors strengthening exercises, and knee extensors strengthening (KES) group will receive quadriceps strengthening exercise.2 groups; hip abductors strengthening (HAS) group a will receive hip abductors strengthening exercises, and knee extensors strengthening (KES) group will receive quadriceps strengthening exercise.

Masking:

None (Open Label)

Primary Purpose:

Treatment

Official Title:

Effect of Hip Abductors Versus Knee Extensor Strengthening on Pain,Function and Quadriceps Isometric Strength in Knee Osteoarthritis

Actual Study Start Date :

Jul 1, 2020

Actual Primary Completion Date :

Nov 1, 2020

Actual Study Completion Date :

Nov 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
Experimental: HAS group hip abductors strengthening group Hip abduction -standing[Ferber et al.,2015]. Sidelying hip abduction(clamshell)[Schache et al.,2016]. lateral leg raise: in brief, the patients lie down on bed on the unaffected side, with the resistance band positioned around the distal thigh of the affected limb.;later, they raise the above lower limbs upwards for about 30 degrees, stay for 5- 10 s and slowly lay down[Xie et al.,2018]. pelvic lift training, specifically, patients stand single-leg off the side at a 10-cm step. Later, they begin with the other limb that is lower than the step level, and contract the stance-limb hip abductor to raise the free leg to the step level while keeping the stance knee extended[Xie et al.,2018]. Stretching Hamstrings [Fukuda et al.,2012]. Number of sets = 3, Repetitions =10 repetitions for each set	Other: Exercises already included in arm/group descriptions.
Active Comparator: KES group knee extensors strengthening group Isometric quadriceps setting Knee extensions from sitting with knee bend to 90 Terminal knee extension from sitting. Stretching Hamstrings Number of sets = 3, Repetitions =10 repetitions for each set	Other: Exercises already included in arm/group descriptions.

Arm

Intervention/Treatment

Experimental: HAS group

hip abductors strengthening group Hip abduction -standing[Ferber et al.,2015]. Sidelying hip abduction(clamshell)[Schache et al.,2016]. lateral leg raise: in brief, the patients lie down on bed on the unaffected side, with the resistance band positioned around the distal thigh of the affected limb.;later, they raise the above lower limbs upwards for about 30 degrees, stay for 5- 10 s and slowly lay down[Xie et al.,2018]. pelvic lift training, specifically, patients stand single-leg off the side at a 10-cm step. Later, they begin with the other limb that is lower than the step level, and contract the stance-limb hip abductor to raise the free leg to the step level while keeping the stance knee extended[Xie et al.,2018]. Stretching Hamstrings [Fukuda et al.,2012]. Number of sets = 3, Repetitions =10 repetitions for each set

Other: Exercises

already included in arm/group descriptions.

Active Comparator: KES group

knee extensors strengthening group Isometric quadriceps setting Knee extensions from sitting with knee bend to 90 Terminal knee extension from sitting. Stretching Hamstrings Number of sets = 3, Repetitions =10 repetitions for each set

Other: Exercises

already included in arm/group descriptions.

Outcome Measures

Primary Outcome Measures

Quadriceps Muscle Strength assessment [6 weeks]
Quadriceps Muscle Strength assessment using Hand held Dynamometer
lower limb functional disability [6 weeks]
Measuring lower limb functional disability using The Arabic version of reduced WOMAC (ArWOMAC) index
Knee function [6 weeks]
Measuring function using The Timed Up & Go Test (TUG):

Eligibility Criteria

Criteria

Ages Eligible for Study:

50 Years to 70 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

Patients with knee OA grade II- III Kellgren- Lawrence scores
Their age is 50-70[Wang et al.,2019].
Body mass index (BMI) 25-30.

Exclusion Criteria:

Patients who had surgical intervention in the knee and/or hip.
Fracture in the lower limbs.
Malignancy
Any associated ligamentous injuries in knee or ankle.
Spinal Cord Injury.
Hormonal imbalance or on hormonal therapy
Knee injection within the last 6 months prior to the study.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Faculty of physical therapy	Cairo		Egypt

Sponsors and Collaborators

Cairo University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:

Aalaa Mohamed El-Amin Sweelam, Teaching Assistant, Cairo University

ClinicalTrials.gov Identifier:

NCT04503304

Other Study ID Numbers:

Hip Abductors strength in KOA

First Posted:

Aug 7, 2020

Last Update Posted:

May 4, 2021

Last Verified:

May 1, 2021

Individual Participant Data (IPD) Sharing Statement:

Yes

Plan to Share IPD:

Yes

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Aalaa Mohamed El-Amin Sweelam, Teaching Assistant, Cairo University

Knee Osteoarthritis AND Hip Abductors AND Quadriceps

Additional relevant MeSH terms:

Osteoarthritis

Osteoarthritis, Knee

Study Results

No Results Posted as of May 4, 2021