Effect Of Strengthening Hip Rotators And Ankle Muscles On Knee Osteoarthritis

Sponsor
Cairo University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05855681
Collaborator
(none)
40
2
8

Study Details

Study Description

Brief Summary

The goal of this clinical trial is to investigate the effect of adding strengthening exercise for hip rotators and ankle muscles to knee exercises on pain, function, muscles strength , and knee proprioception in patients with knee osteoarthritis.

The main question it aims to answer is:
  • What is the effect of adding strengthening exercise for hip rotators and ankle muscles to knee exercises on pain, function, strength of hip rotators and ankle muscles, and knee proprioception in patients with knee osteoarthritis?" Adult male and female diagnosed with unilateral or bilateral knee osteoarthritis, referred from orthopedic surgeons according to inclusion and exclusion criteria will be enrolled in this study, randomly allocated to groups and received exercise for 4 weeks.

  • Control group Patients in this group will receive knee exercises in the form of stretching for hamstring and calf. Strengthening exercises in form of strengthening exercise for quadriceps.

  • Experimental group In addition to the same knee exercise of control group patients will receive strengthening exercise for hip rotators and ankle muscles.

Condition or Disease Intervention/Treatment Phase
  • Other: therapeutic exercises
N/A

Detailed Description

The purpose of the current study is to investigate the effect of adding strengthening exercise for hip rotators and ankle muscles to knee exercises on pain, function, strength of muscles, and knee proprioception in patients with knee osteoarthritis. Adult male and female diagnosed with unilateral or bilateral knee osteoarthritis, referred from orthopedic surgeons according to inclusion and exclusion criteria will be enrolled in this study, randomly allocated to groups and received exercise for 4 weeks. Control group Patients in this group will receive knee exercises in the form of stretching for hamstring and calf. Strengthening exercises in form of strengthening exercise for quadriceps. Experimental group In addition to the same knee exercise of control group patients will receive strengthening exercise for hip rotators and ankle muscles.

Recruited subjects will be screened with consideration of the inclusion and exclusion criteria. Aim of the study and all testing procedures will be verbally explained for eligible subjects and all relevant questions will be answered. If they agreed to participate in the study, an informed consent will be signed . Then, basic demographic information will be collected and patients will start the test. We will measure pain using visual analogue scale, functional level of the knee using Arabic Knee injury and Osteoarthritis Outcome Score questionnaire, isometric muscle strength of quadriceps, hip external and internal rotators, dorsi flexors, planter flexors, evertors and invertor muscles of ankle will be measured by handheld dynamometer and finally knee proprioception will be measured by assessing joint position sense by digital inclinometer. All these measurements will be done at base line and after (4 week) at the end of the treatment program.

All patients will receive knee exercises according to guidelines and previous studies in the form of strengthening exercises that progress from 50% of the

  1. repetition maximum at first 2 week to 70% of 1 repetition maximum at last

  2. weeks, and from mild and moderate Thera band resistance in the first 2 weeks to maximum resistance in the last 2 weeks. In addition to knee muscle strengthening exercises,the experimental group will receive hip rotators and ankle muscles strengthening exercises. Passive stretching for hamstring and calf muscles will be done at the end of all exercises. Stretching will be performed three repetitions per session, holding each stretch for 30 seconds, with 10-seconds rest in between. All exercises will be performed for 30 to 45 minutes per session, 3 times per week for 4 weeks (12 sessions).

Study Design

Study Type:
Interventional
Anticipated Enrollment :
40 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Triple blinded Randomized controlled trialTriple blinded Randomized controlled trial
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Masking Description:
Triple (Participant, Investigator, Outcomes Assessor) (assessor by research assistant, patients and statistician)
Primary Purpose:
Treatment
Official Title:
Effect Of Strengthening Hip Rotators And Ankle Muscles On Knee Osteoarthritis
Anticipated Study Start Date :
Jun 1, 2023
Anticipated Primary Completion Date :
Dec 31, 2023
Anticipated Study Completion Date :
Jan 30, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: experimental group

patients will receive strengthening exercise for hip rotators and ankle muscles in addition to quadriceps strengthening . stretching exercise for hamstring and calf muscle also will be received

Other: therapeutic exercises
strengthening exercise and stretching exercise

Other: control group

patients will receive strengthening exercises for quadriceps and stretching exercise for hamstring and calf muscle.

Other: therapeutic exercises
strengthening exercise and stretching exercise

Outcome Measures

Primary Outcome Measures

  1. pain level [4 weeks]

    assessed by visual analogue scale

  2. functional level [4 weeks]

    assessed by Knee injury and Osteoarthritis Outcome Score

  3. knee proprioception [4 weeks]

    assessed by joint position sense

Secondary Outcome Measures

  1. Hip internal and external rotator strength [4 weeks]

    assessed by handheld dynamometer

  2. Ankle dorsi flexors, planter flexor, invertor and evertor strength [4 weeks]

    assessed by handheld dynamometer

  3. Quadriceps strength [4 weeks]

    assessed by handheld dynamometer

Eligibility Criteria

Criteria

Ages Eligible for Study:
40 Years to 55 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  1. Chronic Knee osteoarthritis with pain for more than 3 months.

  2. Age between 40-55 years .

  3. BMI 25 - 34.9

  4. Kellgren _ Lawrence grad1,2,3 .

  5. Subjects must be referred to the outpatient clinic of the faculty of Physical Therapy, Cairo University with a confirmed diagnosis of unilateral or bilateral (knee with primary affection included) knee osteoarthritis and having one or more of the following criteria:

  6. Morning stiffness for less than 30 min.

  7. Crepitus on active knee movement.

  8. Palpable or radiographic bony enlargement.

  9. Tenderness at joint margins or joint line.

  10. Knee pain over 30 mm on the Visual analogue scale.

Exclusion Criteria:
  • 1- Physical therapy treatment for hip, knee and ankle in the last month. 2-Steroid knee injections in the previous 3 months. 3- hyaluronic acid intraarticular injections in the previous 6 months. 4- History of knee, ankle or hip surgery in the last 2 years. 5- Severe knee malalignment in varus or valgus that requires use of any gait-assistive device.

6- Neurological disease in lower limb 7- Inflammatory arthritis (eg: rheumatoid arthritis). 8- Ankle instability

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Cairo University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Basma Osama Mohammed Galal ALSaadawy, Assistant lecturer, Cairo University
ClinicalTrials.gov Identifier:
NCT05855681
Other Study ID Numbers:
  • P.T.REC/012/004359
First Posted:
May 11, 2023
Last Update Posted:
May 17, 2023
Last Verified:
May 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 17, 2023