Evaluation of Patients With Known or Suspected Heart Disease

Sponsor

National Heart, Lung, and Blood Institute (NHLBI) (NIH)

Overall Status

Completed

CT.gov ID

NCT00001313

Collaborator

(none)

Locations

199.9

Duration (Months)

Study Details

Study Description

Brief Summary

In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).

Patients participating in this study will undergo a general medical evaluation, including blood tests, urine, examination, chest x-ray and electrocardiogram (EKG). In addition, patients may be asked to have an echocardiogram (ultrasound scan of the heart) and to perform an exercise stress test.

These tests are designed to assess the types and causes of patient's heart diseases and to determine if they can participate in other, specific research studies.

Condition or Disease	Intervention/Treatment	Phase
Peripheral Artery Disease Coronary Disease Diabetes and Heart Failure Dilated Cardiomyopathy Heart Failure Renal Artery Stenosis Pulmonary Hypertension

Detailed Description

The principal mission of the NIH is the conduct of research that elucidates biological mechanisms, pathogenesis, and treatment of disease. Patients with known or suspected cardiovascular diseases are referred to NHLBI cardiologists for consideration of participation in clinical research protocols. However, eligibility for participation is often uncertain from referral information or even after an outpatient evaluation. The purpose of this protocol is to permit inpatient evaluation of patients for whom participation in clinical research protocols is under consideration in order to determine protocol eligibility by means of conventional laboratory and cardiovascular testing.

Study Design

Study Type:

Observational

Official Title:

Evaluation of Patients With Known or Suspected Heart Disease (Screening Protocol)

Study Start Date :

May 10, 1992

Study Completion Date :

Jan 6, 2009

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

INCLUSION CRITERIA:

The following is a representative list of the types of patient presentations and potential diagnoses eligible for this protocol:

Coronary artery disease with angina or inducible myocardial ischemia as determined by noninvasive testing.
Cardiomyopathies including congestive phenotypes.
Peripheral artery disease with intermittent claudication or limb-threatening ischemia.
Renovascular disease with uncontrolled hypertension, intermittent pulmonary edema, or evidence of ischemic nephropathy.
Upper extremity peripheral artery disease.
Diabetes with heart failure.
Pulmonary hypertension.

EXCLUSION CRITERIA:

Pregnancy, for those patients who require catheterization-based diagnostics.

Inability to provide informed consent.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Suburban Hospital	Bethesda	Maryland	United States	20814
2	National Institutes of Health Clinical Center, 9000 Rockville Pike	Bethesda	Maryland	United States	20892