Laparoscopic Versus Open Appendectomy in Pregnancy
Study Details
Study Description
Brief Summary
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
Patients' medical records from 2010-2020 were extracted using billing information of the national health insurance fund of Estonia and ICD-10 codes (pregnancy, appendicitis).
Collected data was stored on RedCap electronic database and analyzed with R Studio.
Two group of patients were compared: pregnant patients who had laparoscopic appendectomy and pregnant patients who had open appendectomy.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Pregnant patients who underwent laparoscopic appendectomy Pregnant patients who underwent laparoscopic appendectomy |
Procedure: Appendectomy
Appendectomy - laparoscopic or open
|
| Pregnant patients who underwent open appendectomy Pregnant patients who underwent open appendectomy |
Procedure: Appendectomy
Appendectomy - laparoscopic or open
|
Outcome Measures
Primary Outcome Measures
- Obstetrical outcomes [Pregnancy loss within 9 months from appendectomy]
Pregnancy loss (fetal demise) - rate of cessation of pregnancy before scheduled delivery
Secondary Outcome Measures
- Surgical outcomes [30 days after appendectomy]
Surgical complications - rate of infectious complications within 30 days after appendectomy
Eligibility Criteria
Criteria
Inclusion Criteria:
Women with confirmed pregnancy who underwent appendectomy for acute appendicitis.
Exclusion Criteria:
Women who were not pregnant when having an appendectomy
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | North Estonia Medical Centre | Tallin | Estonia |
Sponsors and Collaborators
- North Estonia Medical Centre
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Lee SH, Lee JY, Choi YY, Lee JG. Laparoscopic appendectomy versus open appendectomy for suspected appendicitis during pregnancy: a systematic review and updated meta-analysis. BMC Surg. 2019 Apr 25;19(1):41. doi: 10.1186/s12893-019-0505-9.
- Prodromidou A, Machairas N, Kostakis ID, Molmenti E, Spartalis E, Kakkos A, Lainas GT, Sotiropoulos GC. Outcomes after open and laparoscopic appendectomy during pregnancy: A meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018 Jun;225:40-50. doi: 10.1016/j.ejogrb.2018.04.010. Epub 2018 Apr 9. Review.
- Zeng Q, Aierken A, Gu SS, Yao G, Apaer S, Anweier N, Wu J, Zhao JM, Li T, Tuxun T. Laparoscopic Versus Open Appendectomy for Appendicitis in Pregnancy: Systematic Review and Meta-Analysis. Surg Laparosc Endosc Percutan Tech. 2021 May 3;31(5):637-644. doi: 10.1097/SLE.0000000000000943.
- 345T-2