The Lasting Change Study

Sponsor
Stanford University (Other)
Overall Status
Active, not recruiting
CT.gov ID
NCT05719129
Collaborator
(none)
1,000
1
12
83.2

Study Details

Study Description

Brief Summary

The study approach is to leverage the most cutting-edge techniques of multi-omics biology, wearable physiology, and digital real-time psychology profiling and using machine learning models to understand the mechanisms underlying the strategies and techniques that enable participants the power to initiate and maintain sustainable behavior change.

Over the years, millions of people worldwide have attended immersive personal development seminars aiming to improve participants' health behaviors and wellness. Nevertheless, there's a scarcity of large-scale studies to assess their effects on behavior change and investigate their mechanism of action. A recent publication by the Science of Behavior Change Program (SOBC), launched by the National Institute of Health (NIH), recognized that: "science has not yet delivered a unified understanding of basic mechanisms of behavior change across a broad range of health-related behaviors, limiting progress in the development and translation of effective and efficacious behavioral intervention." As such, understanding the mechanisms underlying sustainable behavior change is key. The Date With Destiny (DWD) seminar is among the largest worldwide, and tens of thousands of people have already attended and testified to its transformative effect.

The main objective of the study is to uncover the underlying mechanism of behavior change through longitudinal data collection of psychometrics Ecological Momentary Assessments, physiology (wearables), and biology (multi-omics) in study participants.

The study specific objectives include: (1) To evaluate the impact of DWD on sustainable behavior change; (2) To investigate the mechanism of behavior change by collecting longitudinal real-time measurements of psychometrics (e.g., Ecological Momentary Assessments [EMA]), physiological (e.g., heart rate, blood oxygen level, breathing rate, and EDA), and biological (multi-omics analyses) features in study participants; (3) To assess the effect of the DWD on professional fulfillment, resilience, and mental wellness.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Date With Destiny (DWD) Seminar

Detailed Description

The work is done partly as the doctorate thesis of Ziv Lautman (Stanford University, Department of Genetics).

Study Design

Study Type:
Observational
Anticipated Enrollment :
1000 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
The Stanford Lasting Change Study
Actual Study Start Date :
Nov 30, 2022
Anticipated Primary Completion Date :
Dec 1, 2023
Anticipated Study Completion Date :
Dec 1, 2023

Arms and Interventions

Arm Intervention/Treatment
DWD participants

Individuals that voluntarily chose to participate in DWD seminar.

Behavioral: Date With Destiny (DWD) Seminar
6 days of immersive seminar

Outcome Measures

Primary Outcome Measures

  1. Mental performance biomarker index [one-year]

    An algorithm will be used to create an index score using known biomarkers (psychosocial, physiological, and biological) related to participants' personalized mental performance. Higher index scores will indicate a better mental performance index.

Secondary Outcome Measures

  1. Change in participant mental wellness score [baseline through year one]

    Mental wellness scores rated by participants

  2. Participant resilence score [baseline through year one]

    Resilience scores rated by participants

  3. Participant professional fullfilment score [baseline through year one]

    Professional fulfillment scores rated by participants

  4. Participant self efficacy score [baseline through year one]

    Self-efficacy scores rated by participants

  5. Participant quality of life score [baseline through year one]

    Quality of life scores rated by participants

  6. Participant stress score [baseline through year one]

    Stress scores rated by participants

  7. Participant mindset score [baseline through year one]

    Mindset growth scores rated by participants

  8. Participant goals achievement score [baseline through year one]

    Goal achievement scores rated by participants

  9. Participant human needs score [baseline through year one]

    Human needs fulfillment scores rated by participants

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • 18-years-old and older

  • English speaker

  • Live in the US

  • Participate in the DWD seminar (December 2-7, 2022)

Exclusion Criteria:
  • Any physical or mental condition that limits the ability to participate in the study (e.g., answering e-questionnaires and wearing an electronic device)

  • Serious active comorbidity or terminal illness

  • Pregnancy

  • Participation in any other clinical study focusing on psychological or behavioral intervention.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Stanford university Palo Alto California United States 94305

Sponsors and Collaborators

  • Stanford University

Investigators

  • Principal Investigator: Mike Snyder, PhD, Stanford University
  • Principal Investigator: Shahar Lev-Ari, PhD, Stanford University & Tel-Aviv University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Michael Snyder, Chair, Dept. of Genetics, Stanford University
ClinicalTrials.gov Identifier:
NCT05719129
Other Study ID Numbers:
  • 66491
First Posted:
Feb 8, 2023
Last Update Posted:
Feb 8, 2023
Last Verified:
Jan 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Feb 8, 2023