Investigation of the Effects of Motor Cognitive Dual Task Exercises on Cognitive Function, Balance and Functional Capacity in Patients Who Have Undergone Liver Transplantation.

Sponsor
Hasan Kalyoncu University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05909371
Collaborator
(none)
32
1
2
6.5
4.9

Study Details

Study Description

Brief Summary

Liver transplantation is a life-saving treatment of choice for patients with acute or chronic liver failure. Liver transplantation is performed with a graft taken from a living donor or cadaver in patients with end-stage liver failure or who develop various complications regardless of the stage of the disease.In liver diseases, cognitive problems occur as well as physical problems. It has been observed that in some liver diseases, including hepatitis C, Wilson's disease, primary biliary cirrhosis, cognitive dysfunction that negatively affects the quality of life of patients, from mild cognitive problems to hepatic encephalopathy.

Our study will be carried out in Malatya İnönü University Turgut Özal Medical Center Liver Transplant Institute Hospital in order to investigate the effects of motor-cognitive dual-task exercises on cognitive function, balance and functional capacity in liver transplant patients.It will be divided into 2 groups as classical physiotherapy and motor-cognitive exercise. Classical physiotherapy and motor-cognitive exercise programs will be applied to the groups in accordance with the clinical characteristics of the individuals, tolerable, and in a standardized manner specific to the individuals. Evaluations will be made on the first day and at the end of the twenty-fourth session while the patient is in the service before starting the treatment.

Condition or Disease Intervention/Treatment Phase
  • Other: exercise
N/A

Study Design

Study Type:
Interventional
Anticipated Enrollment :
32 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Participant, Care Provider, Outcomes Assessor)
Primary Purpose:
Supportive Care
Official Title:
Physiotherapy and Rehabilitation Doctoral Thesis Work
Anticipated Study Start Date :
Jun 30, 2023
Anticipated Primary Completion Date :
Nov 15, 2023
Anticipated Study Completion Date :
Jan 15, 2024

Arms and Interventions

Arm Intervention/Treatment
Experimental: Classical physiotheraphy

The Program Applied to the Classical Physiotherapy Group The Warm-Up The postural exercises Short Breathing exercises Strengthening exercises Don't sit up Daily Balance exercises Walking exercises Pre-cooling exercise An individual-specific standardized exercise program suitable for clinical characteristics will be applied to patients with a maximum of 1 set of 8-12 repetitions for 30-45 minutes for each exercise (Modified Borg scale 4-6 or maximum heart rate 60-70%).

Other: exercise
Application of two different exercises to liver transplant individuals.

Experimental: Motor cognitive exercise group

The Program to be Applied in addition to the Physiotherapy Program to the Motor-cognitive Exercise Group .Remembering the word. Color/week/month/animal names counting/// girls boy names counting/// Country City names counting. from 50 back to 2 bad, 3 er,// counting from 50 back to 4 er//counting from 100 back to 2 bad 2 bad 3 er 3 er and simple arithmetic problems with single digits. Counting the months of the year// Counting the months of the year starting from any month// Counting the months of the year and 30 31 days.

Other: exercise
Application of two different exercises to liver transplant individuals.

Outcome Measures

Primary Outcome Measures

  1. Evaluation of Cognitive Functions [One day]

    The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points.

  2. Evaluation of Cognitive Functions [One day before the rehabilitation]

    The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points. A day before the rehabilitation

  3. Evaluation of Balance [One day before the rehabilitation]

    Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment. A day before the rehabilitation

  4. Evaluation of Balance [One day]

    Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment.At the time of discharge

  5. Assessment of functional capacity [One day before the rehabilitation]

    In order to determine the functional capacity, a 6-minute walking test was applied. A day before the rehabilitation

  6. Assessment of functional capacity [One day]

    In order to determine the functional capacity, a 6-minute walking test was applied.At the time of discharge

Eligibility Criteria

Criteria

Ages Eligible for Study:
50 Years to 80 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Volunteering to participate

  • Having performed a liver transplant over the age of 50

  • Spontaneous breathing

  • Being hemodynamically stable

  • Ability to read and write

  • Not having an orthopedic disability and functional capacity limitation

  • Being conscious and cooperative

Exclusion Criteria:
  • Not agreeing to participate in the study

  • Not continuing the treatment regularly

  • Having neurological or neuropsychiatric problems

  • Being colorblind

Contacts and Locations

Locations

Site City State Country Postal Code
1 Hasan Kalyoncu University Gaziantep Turkey 27000

Sponsors and Collaborators

  • Hasan Kalyoncu University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
İlker DEMİR, Principal Investigator, Hasan Kalyoncu University
ClinicalTrials.gov Identifier:
NCT05909371
Other Study ID Numbers:
  • Hasankalyoncüüniversityilker
First Posted:
Jun 18, 2023
Last Update Posted:
Jun 18, 2023
Last Verified:
Jun 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No

Study Results

No Results Posted as of Jun 18, 2023