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Long-Term IOP Fluctuation and VF Progression After Triple Procedure

Sponsor
Yonsei University (Other)
Overall Status
Completed
CT.gov ID
NCT00428740
Collaborator
(none)
300
Enrollment
1
Location
2
Duration (Months)
149.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

    Study Design

    Study Type:
    Observational
    Observational Model:
    Defined Population
    Time Perspective:
    Retrospective
    Official Title:
    Long-Term Intraocular Pressure Fluctuation and Visual Field Progression in Glaucoma Patients With Low Intraocular Pressure After Triple Procedure
    Study Start Date :
    Oct 1, 2005
    Study Completion Date :
    Dec 1, 2005

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:

      1. Underwent triple procedure

      2. At leas 3 years of follow-up after surgery

      3. IOP <18mmHg at each postoperative visit

      4. A minimum of 5 visual field examinations

      5. A reference visual field defect score of 16 or less

      6. Good reliability indices of visual field

      Exclusion Criteria:

      1. Any other significant ocular diseases or intraocular surgical histories,

      2. Diseases that may affect visual field or diabetes

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Yonsei University College of Medicine Seoul Korea, Republic of 135-720

      Sponsors and Collaborators

      • Yonsei University

      Investigators

      • Principal Investigator: Gong Je Seong, MD, PhD, Yondgong Severance Hospital, Yonsei University College of Medicine

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00428740
      Other Study ID Numbers:
      • 3-2006-0388
      First Posted:
      Jan 30, 2007
      Last Update Posted:
      Jan 30, 2007
      Last Verified:
      Jan 1, 2007
      Additional relevant MeSH terms:
      Glaucoma

      Study Results

      No Results Posted as of Jan 30, 2007