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MSCT Angiography in Bleeding

Sponsor
Assiut University (Other)
Overall Status
Unknown status
CT.gov ID
NCT03464513
Collaborator
(none)
25
Enrollment
1
Arm
24
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum .

Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation that can be challenging to localize and treat .

There are many diseases that may cause lower gastrointestinal bleeding, including angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel disease, ischemic bowel disease, and infectious bowel disease.

Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of patients, bleeding is massive or recurrent, requiring imaging localization and directed therapy.

Condition or Disease Intervention/Treatment Phase
  • Device: Multislice CT Angiography
 N/A

Detailed Description

Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as high as 40%if there is hemodynamic instability in patients .

Because of the length of GI tract, the multitude of pathologic processes that can result in GI bleeding, imaging plays a primary role in the diagnosis .

Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding .

MSCTA is being increasingly used because it is a widely available, non-invasive and fast diagnostic technique that allows for the visualization of the entire intestinal tract and its lesions, the identification of the vascularity and possible vascular abnormalities. In addition, this technique does not require preparation in patients with acute bleeding.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
25 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Diagnostic
Official Title:
Role of MSCT Angiography in Evaluation of Lower Gastrointestinal Bleeding
Anticipated Study Start Date :
Apr 1, 2018
Anticipated Primary Completion Date :
Apr 1, 2019
Anticipated Study Completion Date :
Apr 1, 2020

Arms and Interventions

Arm Intervention/Treatment
Other: Patients with GIT bleeding

Patients with active lower Gastrointestinal bleeding

Device: Multislice CT Angiography
Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding.

Outcome Measures

Primary Outcome Measures

  1. MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding. [1 hour]

    Multislice ct angiography

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Patients presenting to assiut university hospital with active lower gastrointestinal bleeding.
Exclusion Criteria:
  • Patients whom are sensitive to contrast. Pregnant women. Patients with renal insufficiency

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Mina Gergis Naeem, Principal investigator, Assiut University
ClinicalTrials.gov Identifier:
NCT03464513
Other Study ID Numbers:
  • Angiography
First Posted:
Mar 14, 2018
Last Update Posted:
Mar 14, 2018
Last Verified:
Mar 1, 2018
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Gastrointestinal Hemorrhage
Hemorrhage

Study Results

No Results Posted as of Mar 14, 2018