FLT-PET for Early Detection of Relapse in Patients With Irradiated Lung Cancer

• Sponsor: Rigshospitalet, Denmark (Other)
• Overall Status: Completed
• CT.gov ID: NCT02995889
• Collaborator: (none)
• Enrollment: 64
• Locations: 2
• Arm: 1
• Duration (Months): 63.2
• Patients Per Site: 32
• Patients Per Site Per Month: 0.5

Study Details

Study Description

Brief Summary

This study investigates the feasibility of FLT-PET to improve the diagnosis of relapse in patients with irradiated lung cancer in comparison with FDG-PET/CT.

Condition or Disease	Intervention/Treatment	Phase
Lung Cancer, Nonsmall Cell; Small Cell Lung Cancer	Device: FLT-PET	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 64 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Diagnostic
• Official Title: FLT-PET for Early Detection of Relapse in Patients With Irradiated Lung Cancer
• Study Start Date: Nov 1, 2014
• Actual Primary Completion Date: Feb 7, 2019
• Actual Study Completion Date: Feb 7, 2020

Arms and Interventions

Arm	Intervention/Treatment
Experimental: FLT-PET	Device: FLT-PET

Outcome Measures

Primary Outcome Measures

1. Number of patients with local and/or regional relapse [6 months]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• history with lung cancer, small cell or non-small cell

• radiotherapy of lung cancer ended within the last 24 months

• radiotherapy might be normofractionated or stereotactic

• current suspicion of relapse

• written and oral consent

Exclusion Criteria:

• communication difficulties

• pregnancy or lactation

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Dept. of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet	Copenhagen		Denmark	2100
2	Dept. Respiratory Medicine, Bispebjerg University Hospital	Copenhagen		Denmark	2400

Sponsors and Collaborators

• Rigshospitalet, Denmark

Investigators

• Study Chair: Andreas Kjær, MD phD MDSci, Dept of Clinical Physiology, Nuclear medicine and PET, Rigshospitalet, Denmark

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Tine Nøhr Christensen, MD, research fellow, Rigshospitalet, Denmark
• ClinicalTrials.gov Identifier: NCT02995889
• Other Study ID Numbers: 308_14
• First Posted: Dec 19, 2016
• Last Update Posted: May 9, 2022
• Last Verified: May 1, 2022

• Additional relevant MeSH terms: Lung Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung

Study Results

No Results Posted as of May 9, 2022