HFNC for Induction During Bariatric Surgery Patients.
Study Details
Study Description
Brief Summary
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing bariatric surgery versus the standard of care, which consists in supplemental oxygen with face mask (Venturi mask).
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: HFNC HFNC with a 60 liters per minute flow will be given to the patients before anesthesia induction and before extubation at the end of the surgery |
Procedure: HFNC group
Positive pressure plus supplemental oxygen through a high flow nasal oxygen device
|
| Active Comparator: Standard This patients will be managed as usual care. Pre-oxygenation before induction will be performed with supplemental oxygen but without positive pressure. After extubation patients will be oxygenated through a ventury mask. |
Procedure: Standard group
Supplemental oxygen through venturi mask
|
Outcome Measures
Primary Outcome Measures
- Oxygenation [intraoperative]
The oxygenation (the ratio of partial pressure of arterial oxygen with inspiratory oxygen fraction, PaO2/FIO2) informs of the percentadge of shunt.
Secondary Outcome Measures
- Oxygenation [First 24 postoperative hours]
PaO2/FIO2
- Atelectasis [First 24 postoperative hours]
Atelectasis evaluated with X-ray
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Body mass index > 35 Kg/m2
-
Bariatric surgery
-
Informed consent signed
Exclusion Criteria:
-
age <18yr or >80yr
-
pregnancy or breast-feeding status
-
patients with previous known respiratory disease
-
hemodynamic instability at entry (need of vasopressors or ionotropes at entry or a ventricular assist device
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hospital clínico universitario | Valencia | Spain | 46010 |
Sponsors and Collaborators
- Fundación para la Investigación del Hospital Clínico de Valencia
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Coussa M, Proietti S, Schnyder P, Frascarolo P, Suter M, Spahn DR, Magnusson L. Prevention of atelectasis formation during the induction of general anesthesia in morbidly obese patients. Anesth Analg. 2004 May;98(5):1491-5, table of contents.
- Eichenberger A, Proietti S, Wicky S, Frascarolo P, Suter M, Spahn DR, Magnusson L. Morbid obesity and postoperative pulmonary atelectasis: an underestimated problem. Anesth Analg. 2002 Dec;95(6):1788-92, table of contents.
- Ireland CJ, Chapman TM, Mathew SF, Herbison GP, Zacharias M. Continuous positive airway pressure (CPAP) during the postoperative period for prevention of postoperative morbidity and mortality following major abdominal surgery. Cochrane Database Syst Rev. 2014 Aug 1;(8):CD008930. doi: 10.1002/14651858.CD008930.pub2. Review.
- HFNC-Obese