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Lung Ultrasound for Acute Dyspnea in Emergency Department

Sponsor
University of Turin, Italy (Other)
Overall Status
Completed
CT.gov ID
NCT01287429
Collaborator
Azienda Ospedaliera San Giovanni Battista (Other), San Luigi Gonzaga Hospital (Other), Agnelli Hospital, Italy (Other), Azienda Ospedaliera Ordine Mauriziano di Torino (Other), Martini Hospital, Turin, Italy (Other), Ospedale Cardinal Massaia (Other), Ospedale Santa Croce-Carle Cuneo (Other)
1,005
Enrollment
7
Locations
24
Duration (Months)
143.6
Patients Per Site
6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Dyspnea is a frequent symptom in patients admitted to the Emergency Department (ED); discriminating between cardiogenic and non-cardiogenic dyspnea is a common clinical dilemma. The initial diagnostic work-out is often not very accurate in defining the etiology and the underlying pathophysiology. In the last years, lung ultrasound (US) has emerged as a useful real-time bedside diagnostic tool in the critical patient. The aim of this study was to evaluate the accuracy, reproducibility, and diagnostic impact of pleural and lung US, performed by emergency physicians at the time of patient first presentation to the ED, in identifying cardiac causes of acute dyspnea.

Condition or Disease Intervention/Treatment Phase
  • Other: lung and pleural ultrasound

Study Design

Study Type:
Observational
Actual Enrollment :
1005 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Lung Ultrasound for Acute Dyspnea in Emergency Department - Prospective Multicenter Study on Accuracy, Reproducibility, and Diagnostic Impact of Lung Ultrasound in the Evaluation of Patients With Dyspnea in the Emergency Department
Study Start Date :
Oct 1, 2010
Actual Primary Completion Date :
Oct 1, 2012
Actual Study Completion Date :
Oct 1, 2012

Arms and Interventions

Arm Intervention/Treatment
acute dyspnea

Other: lung and pleural ultrasound
After the initial diagnostic work-out (medical history, physical examination, EKG, arterious blood gas), the emergency physician will classify dyspnoea in cardiogenic or respiratory dyspnoea and write it down in a specific form (clinical form). Immediately after this, lung and pleural ultrasound will be performed: the physician will describe it and evaluate the etiology again (integrated evaluation form). Then a chest X-ray evaluation will be performed for each patient.

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Patients had to present to the ED with a principal complaint of shortness of breath, defined as either the sudden onset of dyspnea with no history of chronic dyspnea or an increase in the severity of chronic dyspnea in the last 48 hours;

    • Presence of an emergency physician with lung US experience at the time of enrollment;

    • US examination within 30 minutes after the start of the clinical evaluation.

    Exclusion Criteria:
    • Dyspnea cases clearly due to neither cardiogenic nor respiratory etiology will considered not eligible.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Emergency Medicine & Surgery Unit - Cardinal Massaia Hospital Asti Italy 14100
    2 Emergency Department - AO Santa Croce e Carle Cuneo Italy
    3 Emergency Medicine Unit - AOU San Luigi Gonzaga Orbassano Italy 10043
    4 Emergency Medicine & Surgery Unit - Pinerolo General Hospital, ASL TO 3 Pinerolo Italy 10064
    5 Emergency Department - AOU San Giovanni Battista Turin Italy 10126
    6 Emergency Medicine and Surgery Unit- AO Mauriziano Turin Italy 10128
    7 Emergency Medicine & Surgery Unit - Martini Hospital, ASL TO 2 Turin Italy 10141

    Sponsors and Collaborators

    • University of Turin, Italy
    • Azienda Ospedaliera San Giovanni Battista
    • San Luigi Gonzaga Hospital
    • Agnelli Hospital, Italy
    • Azienda Ospedaliera Ordine Mauriziano di Torino
    • Martini Hospital, Turin, Italy
    • Ospedale Cardinal Massaia
    • Ospedale Santa Croce-Carle Cuneo

    Investigators

    • Principal Investigator: Emanuele Pivetta, Cancer Epidemiology Unit - University of Turin

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT01287429
    Other Study ID Numbers:
    • CEU-UTurin-001
    First Posted:
    Feb 1, 2011
    Last Update Posted:
    Nov 20, 2012
    Last Verified:
    Oct 1, 2010
    Keywords provided by , ,
    Ultrasonography
    Additional relevant MeSH terms:
    Dyspnea
    Heart Failure
    Emergencies

    Study Results

    No Results Posted as of Nov 20, 2012